Literature DB >> 5327886

Mutagenicity of cycasin aglycone (methylazoxymethanol), a naturally occurring carcinogen.

D W Smith.   

Abstract

Methylazoxymethanol, a carcinogenic and hepatotoxic methylating agent prepared from cycad plants, has been found to be a good mutagen in Salmonella typhimurium.

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Year:  1966        PMID： 5327886     DOI： 10.1126/science.152.3726.1273

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  11 in total

1.  Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.

Authors:  J McCann; E Choi; E Yamasaki; B N Ames
Journal:  Proc Natl Acad Sci U S A       Date:  1975-12       Impact factor: 11.205

2.  Activation of cycasin to a mutagen for Saccharomyces cerevisiae by rat intestinal flora.

Authors:  V W Mayer; C J Goin
Journal:  Appl Environ Microbiol       Date:  1983-02       Impact factor: 4.792

Review 3.  [Molecular aspects of carcinogenesis].

Authors:  R Preussmann
Journal:  Langenbecks Arch Chir       Date:  1971-12

4.  Charting a course toward an understanding of schizophrenia.

Authors:  Joshua A Gordon; Holly Moore
Journal:  Neuron       Date:  2012-11-08       Impact factor: 17.173

5.  Conversion of 2,4,6-trinitrophenol to a mutagen by Pseudomonas aeruginosa.

Authors:  J F Wyman; H E Guard; W D Won; J H Quay
Journal:  Appl Environ Microbiol       Date:  1979-02       Impact factor: 4.792

6.  A simple method for the detection of mutagens in urine: studies with the carcinogen 2-acetylaminofluorene.

Authors:  W E Durston; B N Ames
Journal:  Proc Natl Acad Sci U S A       Date:  1974-03       Impact factor: 11.205

7.  Behavioral and neurological correlates of ALS-parkinsonism dementia complex in adult mice fed washed cycad flour.

Authors:  Jason M B Wilson; Iraj Khabazian; Margaret C Wong; Arash Seyedalikhani; Jaswinder S Bains; Bryce A Pasqualotto; David E Williams; Raymond J Andersen; Rebecca J Simpson; Richard Smith; Ulla-Kate Craig; Leonard T Kurland; Christopher A Shaw
Journal:  Neuromolecular Med       Date:  2002       Impact factor: 3.843

8.  The MAM rodent model of schizophrenia.

Authors:  Daniel J Lodge
Journal:  Curr Protoc Neurosci       Date:  2013

9.  Fecalase: a model for activation of dietary glycosides to mutagens by intestinal flora.

Authors:  G Tamura; C Gold; A Ferro-Luzzi; B N Ames
Journal:  Proc Natl Acad Sci U S A       Date:  1980-08       Impact factor: 11.205

Review 10.  Testing the environment for dispersed mutagens: use of plant bioconcentrators coupled with microbial mutagen assays.

Authors:  W S Barnes; E J Klekowski
Journal:  Environ Health Perspect       Date:  1978-12       Impact factor: 9.031
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