Literature DB >> 508093

Effect of trisodium phosphonoformate in genital infection of female guinea pigs with herpes simplex virus type 2.

S Alenius, H Nordlinder.   

Abstract

A genital herpesvirus type 2 infection in guinea pigs has been used to evaluate the inhibitory effect of phosphonoformate on the infection. An early topical treatment prevented the appearance of vesicles and histopathological changes and no virus could be recovered. When treatment, either topical or both systemic and topical, was delayed to 24 hours post infection no therapeutic effect was observed.

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Year:  1979        PMID： 508093     DOI： 10.1007/bf01317491

Source DB:  PubMed          Journal:  Arch Virol        ISSN： 0304-8608            Impact factor:   2.574


  21 in total

1.  Inhibition of herpesvirus replication and herpesvirus-induced deoxyribonucleic acid polymerase by phosphonoformate.

Authors:  J M Reno; L F Lee; J A Boezi
Journal:  Antimicrob Agents Chemother       Date:  1978-02       Impact factor: 5.191

2.  Therapeutic effect of trisodium phosphonoformate on cutaneous herpesvirus infection in guinea pigs.

Authors:  S Alenius; Z Dinter; B Oberg
Journal:  Antimicrob Agents Chemother       Date:  1978-09       Impact factor: 5.191

3.  Antibody to genital herpes simplex virus: association with cervical atypia and carcinoma in situ.

Authors:  L Aurelian; I Royston; H J Davis
Journal:  J Natl Cancer Inst       Date:  1970-09       Impact factor: 13.506

4.  Genital herpesvirus hominis type 2 infection: an experimental model in cebus monkeys.

Authors:  A J Nahmias; W T London; L W Catalano; D A Fuccillo; J L Sever; C Graham
Journal:  Science       Date:  1971-01-22       Impact factor: 47.728

5.  Genital herpetic infection. Association with cervical dysplasia and carcinoma.

Authors:  Z M Naib; A J Nahmias; W E Josey; J H Kramer
Journal:  Cancer       Date:  1969-04       Impact factor: 6.860

6.  Characterization of herpes simplex virus strains differing in their effects on social behaviour of infected cells.

Authors:  P M Ejercito; E D Kieff; B Roizman
Journal:  J Gen Virol       Date:  1968-05       Impact factor: 3.891

7.  Kethoxal for treatment of cutaneous herpes simplex.

Authors:  G E Underwood
Journal:  Proc Soc Exp Biol Med       Date:  1968-10

8.  Herpes genitalis in guinea-pigs. II. Morphological studies in female guinea-pigs infected with Herpesvirus hominis type 2.

Authors:  G Krinke; F Zák; B Lukás; W Wiesendanger; K H Schmidt-Ruppin
Journal:  Arch Virol       Date:  1975       Impact factor: 2.574

9.  Comparison of the therapeutic effects of five antiviral agents on cutaneous herpesvirus infection in guinea pigs.

Authors:  S Alenius; B Oberg
Journal:  Arch Virol       Date:  1978       Impact factor: 2.574

10.  Disodium phosphonoacetate in cream base as a possible topical treatment for skin lesions of herpes simplex virus in cebus monkeys.

Authors:  A E Palmer; W T London; J L Sever
Journal:  Antimicrob Agents Chemother       Date:  1977-10       Impact factor: 5.191
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  3 in total

1.  Treatment of primary acute genital herpes in guinea pigs by intraperitoneal administration of fluoropyrimidines.

Authors:  D R Mayo; G D Hsiung
Journal:  Antimicrob Agents Chemother       Date:  1984-09       Impact factor: 5.191

2.  Xylotubercidin against herpes simplex virus type 2 in mice.

Authors:  E De Clercq; M J Robins
Journal:  Antimicrob Agents Chemother       Date:  1986-11       Impact factor: 5.191

Review 3.  Rapid and accurate viral diagnosis.

Authors:  M L Landry; D R Mayo; G D Hsiung
Journal:  Pharmacol Ther       Date:  1989       Impact factor: 12.310
  3 in total

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