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Literature DB >> 4858786

Inhibition of herpes virus-induced cell fusion by concanavalin A, antisera, and 2-deoxy-D-glucose.

Abstract

Pseudorabies virus-induced cell fusion in rabbit kidney cells can be prevented by Concanavalin A added early after infection. The infected cells are not agglutinated and the infectivity of cell-free virus is not reduced. Sera from productively infected animals also inhibit polykaryocytosis, whereas a hyperimmune serum directed against virus structural components has no effect. 2-Deoxy-d-glucose reversibly disturbs virus-induced fusion and reduces significantly the virus infectivity.

Entities: Chemical Species

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Year: 1974 PMID： 4858786 PMCID： PMC355516 DOI： 10.1128/JVI.14.2.307-314.1974

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

27 in total

1. Studies on the biogenesis of herpesvirus envelope.

Authors: T Ben-Porat; A S Kaplan
Journal: Nature Date: 1972-01-21 Impact factor: 49.962

2. Effect of Concanavalin A on cells infected with enveloped RNA viruses.

Authors: H Becht; R Rott; H D Klenk
Journal: J Gen Virol Date: 1972-01 Impact factor: 3.891

3. Binding of radioactively labelled concanavalin A and wheat germ agglutinin to normal and virus-transformed cells.

Authors: B Ozanne; J Sambrook
Journal: Nat New Biol Date: 1971-08-04

4. The inhibitory effect of compound 48-80 on the formation of giant cells induced by herpesvirus hominis.

Authors: D Falke; G F Kahl
Journal: J Gen Virol Date: 1971-03 Impact factor: 3.891

5. Characterization of herpes simplex virus strains differing in their effects on social behaviour of infected cells.

Authors: P M Ejercito; E D Kieff; B Roizman
Journal: J Gen Virol Date: 1968-05 Impact factor: 3.891

6. Electron microscopy of herpes simplex virus. IV. Studies with ferritin-conjugated antibodies.

Authors: S Nii; C Morgan; H M Rose; K C Hsu
Journal: J Virol Date: 1968-10 Impact factor: 5.103

7. Surface antigen on chick kidney cells infected with the herpesvirus of Marek's disease.

Authors: J H Chen; H G Purchase
Journal: Virology Date: 1970-02 Impact factor: 3.616

8. Immunizing effect of photoinactivated pseudorabies virus.

Authors: H C Borgen; L Espensen
Journal: Zentralbl Bakteriol Orig Date: 1970

9. Synthesis of proteins in cells infected with herpesvirus, VI. Characterization of the proteins of the viral membrane.

Authors: A S Kaplan; T Ben-Porat
Journal: Proc Natl Acad Sci U S A Date: 1970-07 Impact factor: 11.205

10. Relation between Epstein-Barr viral and cell membrane immunofluorescence of Burkitt tumor cells. I. Dependence of cell membrane immunofluorescence on presence of EB virus.

Authors: G Klein; G Pearson; J S Nadkarni; J J Nadkarni; E Klein; G Henle; W Henle; P Clifford
Journal: J Exp Med Date: 1968-11-01 Impact factor: 14.307

14 in total

5. Involvement of actin-containing microfilaments in HSV-induced cytopathology and the influence of inhibitors of glycosylation.

Authors: U Heeg; H P Dienes; S Müller; D Falke
Journal: Arch Virol Date: 1986 Impact factor: 2.574

10. Alterations of neutral glycolipids in cells infected with syncytium-producing mutants of herpes simplex virus type 1.

Authors: M A Ruhlig; S Person
Journal: J Virol Date: 1977-11 Impact factor: 5.103

Inhibition of herpes virus-induced cell fusion by concanavalin A, antisera, and 2-deoxy-D-glucose.

1. Studies on the biogenesis of herpesvirus envelope.

2. Effect of Concanavalin A on cells infected with enveloped RNA viruses.

3. Binding of radioactively labelled concanavalin A and wheat germ agglutinin to normal and virus-transformed cells.

4. The inhibitory effect of compound 48-80 on the formation of giant cells induced by herpesvirus hominis.

5. Characterization of herpes simplex virus strains differing in their effects on social behaviour of infected cells.

6. Electron microscopy of herpes simplex virus. IV. Studies with ferritin-conjugated antibodies.

7. Surface antigen on chick kidney cells infected with the herpesvirus of Marek's disease.

8. Immunizing effect of photoinactivated pseudorabies virus.

9. Synthesis of proteins in cells infected with herpesvirus, VI. Characterization of the proteins of the viral membrane.

10. Relation between Epstein-Barr viral and cell membrane immunofluorescence of Burkitt tumor cells. I. Dependence of cell membrane immunofluorescence on presence of EB virus.

1. Normal and pseudorabies virus infected primary nerve cell cultures in scanning electron microscopy.

2. Effect of 2-deoxy-D-glucose on herpesvirus-induced inhibition of cellular DNA synthesis.

3. Preliminary biochemical characterization of the factors(s) responsible for herpesvirus-induced exogenous fusion.

4. Structural and growth characteristics of infectious bursal disease virus.

5. Involvement of actin-containing microfilaments in HSV-induced cytopathology and the influence of inhibitors of glycosylation.

6. Lack of efficacy of 2-deoxy-D-glucose in the treatment of experimental herpes genitalis in guinea pigs.

7. Fluorosugars inhibit biological properties of different enveloped viruses.

8. Effects of 2-deoxyglucose, glucosamine, and mannose on cell fusion and the glycoproteins of herpes simplex virus.

9. Immunoprecipitation of herpes simplex virus type 1 antigens with different antisera and human cerebrospinal fluids.

10. Alterations of neutral glycolipids in cells infected with syncytium-producing mutants of herpes simplex virus type 1.