Literature DB >> 7201777

Lack of efficacy of 2-deoxy-D-glucose in the treatment of experimental herpes genitalis in guinea pigs.

W M Shannon, G Arnett, D J Drennen.   

Abstract

Topical treatment of herpes genitalis in female guinea pigs with 2-deoxy-D-glucose in either agarose gels or miconazole nitrate ointments failed to prevent the development of genital lesions or to reduce the mean titers of recoverable virus in vaginal swabs from infected animals. In contrast, phosphonoacetic acid was therapeutically effective.

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Year:  1982        PMID： 7201777      PMCID： PMC181926          DOI： 10.1128/AAC.21.3.513

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  14 in total

1.  Herpes simplex virus protein synthesis in the presence of 2-deoxy-D-glucose.

Authors:  R J Courtney
Journal:  Virology       Date:  1976-08       Impact factor: 3.616

2.  The effect of herpesvirus infection and 2-deoxy-D-glucose on glycosphingolipids in BHK-21 cells.

Authors:  E K Ray; H A Blough
Journal:  Virology       Date:  1978-07-01       Impact factor: 3.616

3.  Timing of some of the molecular events required for cell fusion induced by herpes simplex virus type 1.

Authors:  K G Kousoulas; S Person; T C Holland
Journal:  J Virol       Date:  1978-09       Impact factor: 5.103

4.  Treatment of experimental herpesvirus infections with phosphonoformate and some comparisons with phosphonoacetate.

Authors:  E R Kern; L A Glasgow; J C Overall; J M Reno; J A Boezi
Journal:  Antimicrob Agents Chemother       Date:  1978-12       Impact factor: 5.191

5.  Effect of 2-deoxy-D-glucose on cell fusion induced by Newcastle disease and herpes simplex viruses.

Authors:  W R Gallaher; D B Levitan; H A Blough
Journal:  Virology       Date:  1973-09       Impact factor: 3.616

6.  Effects of 2-deoxy-D-glucose on herpes simplex virus replication.

Authors:  R J Courtney; S M Steiner; M Benyesh-Melnick
Journal:  Virology       Date:  1973-04       Impact factor: 3.616

7.  A new approach to viral chemotherapy. Inhibitors of glycoprotein synthesis.

Authors:  E K Ray; D B Levitan; B L Halpern; H A Blough
Journal:  Lancet       Date:  1974-09-21       Impact factor: 79.321

8.  Effects of 2-deoxyglucose, glucosamine, and mannose on cell fusion and the glycoproteins of herpes simplex virus.

Authors:  R W Knowles; S Person
Journal:  J Virol       Date:  1976-05       Impact factor: 5.103

9.  Successful treatment of human genital herpes infections with 2-deoxy-D-glucose.

Authors:  H A Blough; R L Giuntoli
Journal:  JAMA       Date:  1979-06-29       Impact factor: 56.272

10.  Inhibition of herpes virus-induced cell fusion by concanavalin A, antisera, and 2-deoxy-D-glucose.

Authors:  H Ludwig; H Becht; R Rott
Journal:  J Virol       Date:  1974-08       Impact factor: 5.103
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  5 in total

1.  Antiviral activity of 5-ethyl-2'-deoxyuridine against herpes simplex viruses in cell culture, mice, and guinea pigs.

Authors:  R F Schinazi; R T Scott; J Peters; V Rice; A J Nahmias
Journal:  Antimicrob Agents Chemother       Date:  1985-10       Impact factor: 5.191

2.  Treatment of primary acute genital herpes in guinea pigs by intraperitoneal administration of fluoropyrimidines.

Authors:  D R Mayo; G D Hsiung
Journal:  Antimicrob Agents Chemother       Date:  1984-09       Impact factor: 5.191

3.  Activity of (+)-cyclaradine (Sch 31172) against herpes simplex virus in vitro and in vivo.

Authors:  J Schwartz; M Ostrander; N J Butkiewicz; M Lieberman; C Lin; J Lim; G H Miller
Journal:  Antimicrob Agents Chemother       Date:  1987-01       Impact factor: 5.191

4.  2-deoxy-D-glucose as India's Response to COVID-19: A Commitment or Conceit?

Authors:  Ritwik Ghosh; Dipayan Roy; Subhankar Chatterjee; Julián Benito-León
Journal:  J Community Hosp Intern Med Perspect       Date:  2022-05-02

Review 5.  Inhibitors of protein glycosylation and glycoprotein processing in viral systems.

Authors:  R Datema; S Olofsson; P A Romero
Journal:  Pharmacol Ther       Date:  1987       Impact factor: 12.310
  5 in total

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