Literature DB >> 4688860

Mechanism of chymotrypsin. Structure, reactivity, and nonproductive binding relationships.

J Fastrez, A R Fersht.   

Abstract

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Year:  1973        PMID： 4688860     DOI： 10.1021/bi00730a008

Source DB:  PubMed          Journal:  Biochemistry        ISSN： 0006-2960            Impact factor:   3.162


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  12 in total

1.  PH-dependence of the steady-state rate of a two-step enzymic reaction.

Authors:  K Brocklehurst; H B Dixon
Journal:  Biochem J       Date:  1976-04-01       Impact factor: 3.857

2.  Detection and accumulation of tetrahedral intermediates in elastase catalysis.

Authors:  A L Fink; P Meehan
Journal:  Proc Natl Acad Sci U S A       Date:  1979-04       Impact factor: 11.205

3.  Specificity in the hydrolysis of N-acyl-L-phenylalanine 4-nitroanilides by chymotrypsin.

Authors:  H D Jakubke; H Däumer; A Könnecke; P Kuhl; J Fischer
Journal:  Experientia       Date:  1980-09-15

Review 4.  Theories of enzyme specificity and their application to proteases and aminoacyl-transfer RNA synthetases.

Authors:  H R Bosshard
Journal:  Experientia       Date:  1976-08-15

5.  Acylation of alpha-chymotrypsin by oxygen and sulfur esters of specific substrates: kinetic evidence for a tetrahedral intermediate.

Authors:  H Hiroara; M L Bender; R S Stark
Journal:  Proc Natl Acad Sci U S A       Date:  1974-05       Impact factor: 11.205

6.  The specificity of cross-reactivity: promiscuous antibody binding involves specific hydrogen bonds rather than nonspecific hydrophobic stickiness.

Authors:  Leo C James; Dan S Tawfik
Journal:  Protein Sci       Date:  2003-10       Impact factor: 6.725

7.  Modulation of the general anesthetic sensitivity of a protein: a transition between two forms of firefly luciferase.

Authors:  G W Moss; N P Franks; W R Lieb
Journal:  Proc Natl Acad Sci U S A       Date:  1991-01-01       Impact factor: 11.205

8.  Targeted rescue of a destabilized mutant of p53 by an in silico screened drug.

Authors:  Frank M Boeckler; Andreas C Joerger; Gaurav Jaggi; Trevor J Rutherford; Dmitry B Veprintsev; Alan R Fersht
Journal:  Proc Natl Acad Sci U S A       Date:  2008-07-23       Impact factor: 11.205

9.  A study of the stabilization of tetrahedral adducts by trypsin and delta-chymotrypsin.

Authors:  M D Finucane; J P Malthouse
Journal:  Biochem J       Date:  1992-09-15       Impact factor: 3.857

10.  How Large Should the QM Region Be in QM/MM Calculations? The Case of Catechol O-Methyltransferase.

Authors:  Heather J Kulik; Jianyu Zhang; Judith P Klinman; Todd J Martínez
Journal:  J Phys Chem B       Date:  2016-10-28       Impact factor: 2.991
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