Literature DB >> 4612523

Utilization of two distinct modes of replication by a hybrid plasmid constructed in vitro from separate replicons.

K Timmis, F Cabello, S N Cohen.   

Abstract

A hybrid plasmid, pSC134, that codes for two distinct sets of replication functions has been constructed in vitro by ligation of EcoRI endonuclease-cleaved pSC101 and Col E1 plasmid replicons, and has been introduced into Escherichia coli by transformation. The replication properties of the pSC134 plasmid in DNA polymerase I-defective mutants or in the presence of chloramphenicol indicate that this hybrid plasmid can utilize the functionally distinct modes of replication specified by both of its parent replicons.

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Year:  1974        PMID： 4612523      PMCID： PMC433926          DOI： 10.1073/pnas.71.11.4556

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  29 in total

1.  DNA polymerase as a requirement for the maintenance of the bacterial plasmid colicinogenic factor E1.

Authors:  D T Kingsbury; D R Helinski
Journal:  Biochem Biophys Res Commun       Date:  1970-12-24       Impact factor: 3.575

2.  Non-chromosomal antibiotic resistance in bacteria. II. Molecular nature of R-factors isolated from Proteus mirabilis and Escherichia coli.

Authors:  S N Cohen; C A Miller
Journal:  J Mol Biol       Date:  1970-06-28       Impact factor: 5.469

3.  Replication of a bacterial plasmid and an episome in Escherichia coli.

Authors:  M Bazaral; D R Helinski
Journal:  Biochemistry       Date:  1970-01-20       Impact factor: 3.162

4.  Studies on Escherichia coli sex factors. I. Specific labeling of F'Lac DNA.

Authors:  D R Freifelder; D Freifelder
Journal:  J Mol Biol       Date:  1968-02-28       Impact factor: 5.469

5.  Supercoiled circular DNA-protein complex in Escherichia coli: purification and induced conversion to an opern circular DNA form.

Authors:  D B Clewell; D R Helinski
Journal:  Proc Natl Acad Sci U S A       Date:  1969-04       Impact factor: 11.205

6.  The problems of drug-resistant pathogenic bacteria. Regulation of R-factor replication in Proteus mirabilis.

Authors:  D J Kopecko; J D Punch
Journal:  Ann N Y Acad Sci       Date:  1971-06-11       Impact factor: 5.691

7.  Composite circular forms of R factor deoxyribonucleic acid molecules.

Authors:  T Nisioka; M Mitani; R Clowes
Journal:  J Bacteriol       Date:  1969-01       Impact factor: 3.490

Review 8.  Circular DNA.

Authors:  D R Helinski; D B Clewell
Journal:  Annu Rev Biochem       Date:  1971       Impact factor: 23.643

9.  Specific labeling and physical characterization of R-factor deoxyribonucleic acid in Escherichia coli.

Authors:  R P Silver; S Falkow
Journal:  J Bacteriol       Date:  1970-10       Impact factor: 3.490

10.  Plasmid ColEl as a molecular vehicle for cloning and amplification of DNA.

Authors:  V Hershfield; H W Boyer; C Yanofsky; M A Lovett; D R Helinski
Journal:  Proc Natl Acad Sci U S A       Date:  1974-09       Impact factor: 11.205
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  48 in total

Review 1.  Colicinogeny and related phenomena.

Authors:  K G Hardy
Journal:  Bacteriol Rev       Date:  1975-12

2.  Cloning, isolation, and characterization of replication regions of complex plasmid genomes.

Authors:  K Timmis; F Cabello; S N Cohen
Journal:  Proc Natl Acad Sci U S A       Date:  1975-06       Impact factor: 11.205

3.  Evaluation of several enrichment procedures for the isolation of recombinant plasmid DNA.

Authors:  A Rosner; R N Bastos; H Aviv
Journal:  Mol Biol Rep       Date:  1979-02-15       Impact factor: 2.316

4.  Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid.

Authors:  A C Chang; S N Cohen
Journal:  J Bacteriol       Date:  1978-06       Impact factor: 3.490

5.  Uniform nomenclature for bacterial plasmids: a proposal.

Authors:  R P Novick; R C Clowes; S N Cohen; R Curtiss; N Datta; S Falkow
Journal:  Bacteriol Rev       Date:  1976-03

6.  The Pseudomonas cepacia 249 chromosomal penicillinase is a member of the AmpC family of chromosomal beta-lactamases.

Authors:  R Proenca; W W Niu; G Cacalano; A Prince
Journal:  Antimicrob Agents Chemother       Date:  1993-04       Impact factor: 5.191

7.  Phasmid P4: manipulation of plasmid copy number and induction from the integrated state.

Authors:  R Lagos; R Goldstein
Journal:  J Bacteriol       Date:  1984-04       Impact factor: 3.490

8.  Plasmid replication functions. II. Cloning analysis of the repA replication region of antibiotic resistance plasmid R6-5.

Authors:  I Andrés; P M Slocombe; F Cabello; J K Timmis; R Lurz; H J Burkardt; K N Timmis
Journal:  Mol Gen Genet       Date:  1979-01-05

9.  Isolation and characterization of replication-deficient mutants of ColE1 plasmids.

Authors:  T Hashimoto-Gotoh; J Inselburg
Journal:  J Bacteriol       Date:  1979-08       Impact factor: 3.490

10.  Effect of dna mutations on the replication of plasmid pSC101 in Escherichia coli K-12.

Authors:  K Hasunuma; M Sekiguchi
Journal:  J Bacteriol       Date:  1979-03       Impact factor: 3.490
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