Literature DB >> 4597115

Potentiation of the antifungal effects of antibiotics by amphotericin B.

C N Kwan, G Medoff, G S Kobayashi, D Schlessinger, H J Raskas.   

Abstract

Amphotericin B was found to potentiate the antifungal effects of mycophenolic acid glucuronide, tetracycline, and actinomycin D by increasing the penetration of these antibiotics through the fungal cytoplasmic membrane. Because the fungi were over 100 times more susceptible than animal cells to these effects of amphotericin B, these observations might have clinical application.

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Year:  1972        PMID： 4597115      PMCID： PMC444268          DOI： 10.1128/AAC.2.2.61

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  7 in total

Review 1.  Antibiotic interaction with model membranes.

Authors:  S C Kinsky
Journal:  Annu Rev Pharmacol       Date:  1970       Impact factor: 13.820

2.  Synergistic action of amphotericin B and 5-fluorocytosine against yeast-like organisms.

Authors:  G Medoff; M Comfort; G S Kobayashi
Journal:  Proc Soc Exp Biol Med       Date:  1971-11

3.  Possible in situ activation of mycophenolic acid by beta-glucuronidase.

Authors:  M J Sweeney; D H Hoffmann; G A Poore
Journal:  Cancer Res       Date:  1971-04       Impact factor: 12.701

4.  Inhibitors of protein synthesis by ribosomes of the 80-S type.

Authors:  E Battaner; D Vazquez
Journal:  Biochim Biophys Acta       Date:  1971-12-16

5.  Potentiation of rifampicin and 5-fluorocytosine as antifungal antibiotics by amphotericin B (yeast-membrane permeability-ribosomal RNA-eukaryotic cell-synergism).

Authors:  G Medoff; G S Kobayashi; C N Kwan; D Schlessinger; P Venkov
Journal:  Proc Natl Acad Sci U S A       Date:  1972-01       Impact factor: 11.205

6.  Macromolecule synthesis in temperature-sensitive mutants of yeast.

Authors:  L H Hartwell
Journal:  J Bacteriol       Date:  1967-05       Impact factor: 3.490

7.  The inhibition of nucleic acid synthesis by mycophenolic acid.

Authors:  T J Franklin; J M Cook
Journal:  Biochem J       Date:  1969-07       Impact factor: 3.857
  7 in total
  36 in total

Review 1.  New antifungal therapy in ophthalmology.

Authors:  T W Lieberman; I H Leopold
Journal:  Trans Am Ophthalmol Soc       Date:  1973

2.  Assessment of the effect of amphotericin B on the vitality of Candida albicans.

Authors:  R S Liao; R P Rennie; J A Talbot
Journal:  Antimicrob Agents Chemother       Date:  1999-05       Impact factor: 5.191

Review 3.  Antifungal activity of nonantifungal drugs.

Authors:  J Afeltra; P E Verweij
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2003-06-26       Impact factor: 3.267

4.  Acceleration of yeast autolysis by chemical methods for production of intracellular enzymes.

Authors:  Klaus Breddam; Thorkild Beenfeldt
Journal:  Appl Microbiol Biotechnol       Date:  1991-06       Impact factor: 4.813

5.  Amphotericin B and filipin effects on L and HeLa cells: dose response.

Authors:  J Kotler-Brajtburg; G Medoff; D Schlessinger; G S Kobayashi
Journal:  Antimicrob Agents Chemother       Date:  1977-05       Impact factor: 5.191

6.  Potentiation of antifungal activity of amphotericin B by azithromycin against Aspergillus species.

Authors:  M H Nguyen; C J Clancy; Y C Yu; A S Lewin
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1997-11       Impact factor: 3.267

7.  Activity of sulfa drugs and dihydrofolate reductase inhibitors against Candida albicans.

Authors:  K Bush; J S Freudenberger; D S Slusarchyk; R B Sykes; E Meyers
Journal:  Experientia       Date:  1982-04-15

8.  In vitro susceptibilities of Naegleria fowleri strain HB-1 to selected antimicrobial agents, singly and in combination.

Authors:  K K Lee; S L Karr; M M Wong; P D Hoeprich
Journal:  Antimicrob Agents Chemother       Date:  1979-08       Impact factor: 5.191

9.  Sterol-polyene antibiotic complexation: probe of membrane structure.

Authors:  R Bittman
Journal:  Lipids       Date:  1978-10       Impact factor: 1.880

10.  Therapy of murine aspergillosis with amphotericin B in combination with rifampin of 5-fluorocytosine.

Authors:  J Arroyo; G Medoff; G S Kobayashi
Journal:  Antimicrob Agents Chemother       Date:  1977-01       Impact factor: 5.191
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