| Literature DB >> 723481 |
Abstract
Polyene antibiotics are useful tools for studying the role of sterols in biological membranes. The interaction of polyene antibiotics with membrane-bound sterols in artificial membrane systems, prokaryotic and eukaryotic cells, and lipid-containing viruses is reviewed. The pentaene macrolide, filipin, is shown to serve as a probe of phosphatidylcholine-sterol interaction and of the localization of cholesterol in the membrane of mycoplasmas.Entities:
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Year: 1978 PMID: 723481 DOI: 10.1007/bf02533746
Source DB: PubMed Journal: Lipids ISSN: 0024-4201 Impact factor: 1.880