Literature DB >> 4525452

Blastic transformtion of mouse spleen lymphocytes by a water-soluble mitogen extracted from Nocardia.

C Bona, C Damais, L Chedid.   

Abstract

A water-soluble extract of Nocardia markedly increased in vitro [(3)H]thymidine incorporation by mouse spleen lymphocytes. The blastogenic activity of the extract and lipopolysaccharide was studied comparatively on various mouse lymphocyte subpopulations. The data obtained by [(3)H]thymidine incorporation and by electron microscopy have demonstrated that this preparation stimulates selectively mouse bone-marrow-derived cortisone-sensitive lymphocytes. This stimulation is related neither to a natural infection of mice with Nocardia organisms nor to the presence in Nocardia water-soluble mitogen of a lipopolysaccharide contaminant or of a lipopolysaccharide-like material.

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Year:  1974        PMID： 4525452      PMCID： PMC388284          DOI： 10.1073/pnas.71.5.1602

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  16 in total

1.  Effect of hydrocortisone on the reactivity of thymus and spleen cells of mice to in vitro stimulation.

Authors:  T L Vischer
Journal:  Immunology       Date:  1972-11       Impact factor: 7.397

2.  Structure of the lymphocyte membrane. II. Evidence of two classes of Ig on the surface of rabbit lymphocytes during primary response to sheep red blood cells using inhibition of rosette-forming cells and combined ultrastructural autoradiographic and peroxydase methods.

Authors:  C A Bona; I Trebiciavsky; A Anteunis; C Heuclin; R Robineaux
Journal:  Eur J Immunol       Date:  1972-10       Impact factor: 5.532

Review 3.  Cell cooperation in the immune response.

Authors:  J H Playfair
Journal:  Clin Exp Immunol       Date:  1971-06       Impact factor: 4.330

4.  Preparation and biological properties of water-soluble adjuvant fractions from delipidated cells of Mycobacterium smegmatis and Nocardia opaca.

Authors:  A Adam; R Ciorbaru; J F Petit; E Lederer; L Chedid; A Lamensans; F Parant; M Parant; J P Rosselet; F M Berger
Journal:  Infect Immun       Date:  1973-06       Impact factor: 3.441

5.  Evidence for a small pool of immunocompetent cells in the mouse thymus.

Authors:  H Blomgren; B Andersson
Journal:  Exp Cell Res       Date:  1969-10       Impact factor: 3.905

6.  Lymphocyte activation. I. Response of T and B lymphocytes to phytomitogens.

Authors:  G Janossy; M F Greaves
Journal:  Clin Exp Immunol       Date:  1971-10       Impact factor: 4.330

7.  Ultrastructure of cells present in lymph nodes during the development of contact sensitivity.

Authors:  S De Petris; G Karlsbad; B Pernis; J L Turk
Journal:  Int Arch Allergy Appl Immunol       Date:  1966

8.  Electron microscopic observations on antibody-producing lymph node cells.

Authors:  T N Harris; K Hummeler; S Harris
Journal:  J Exp Med       Date:  1966-01-01       Impact factor: 14.307

9.  The mitogenic effect of lipopolysaccharide on bone marrow-derived mouse lymphocytes. Lipid A as the mitogenic part of the molecule.

Authors:  J Andersson; F Melchers; C Galanos; O Lüderitz
Journal:  J Exp Med       Date:  1973-04-01       Impact factor: 14.307

10.  Thymus-marrow immunocompetence. V. Hydrocortisone-resistant cells and processes in the hemolytic antibody response of mice.

Authors:  J J Cohen; H N Claman
Journal:  J Exp Med       Date:  1971-05-01       Impact factor: 14.307
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  21 in total

1.  Presence and subcellular localization of two distinct mitogenic fractions in the cells of Nocardia rubra and Nocardia opaca: preparation of soluble mitogenic peptidoglycan fractions.

Authors:  R Ciorbaru; J F Petit; E Lederer; E Zissman; C Bona; L Chedid
Journal:  Infect Immun       Date:  1976-04       Impact factor: 3.441

2.  Failure of endotoxin to increase nonspecific resistance to infection of lipopolysaccharide low-responder mice.

Authors:  L Chedid; M Parant; C Damais; F Parant; D Juy; A Galelli
Journal:  Infect Immun       Date:  1976-03       Impact factor: 3.441

3.  Nocardia water-soluble mitogen and lipopolysaccharide. Comparative study of two adjuvants and B-cell mitogens in mice.

Authors:  I Lowy; C Bona; R Ciorbaru; L Chedid
Journal:  Immunology       Date:  1977-06       Impact factor: 7.397

4.  The role of rabbit Ia molecules in immune functions as determined with the use of an anti-Ia monoclonal antibody.

Authors:  S A Lobel; K L Knight
Journal:  Immunology       Date:  1984-01       Impact factor: 7.397

5.  Rabbit lymphoid cells. II. Anti-allotype antisera, lipopolysaccharide and other bacterial and fungal mitogens as probes for the identification of B-cell subpopulations.

Authors:  P N Shek; C T Chou; S Dubiski; B Cinader
Journal:  Immunology       Date:  1976-07       Impact factor: 7.397

6.  B-lymphocyte activation with an extract of Nocardia brasiliensis.

Authors:  L Ortiz-Oritz; D E Parks; J S Lopez; W O Weigle
Journal:  Infect Immun       Date:  1979-08       Impact factor: 3.441

7.  Immunological defect and its correction in the osteopetrotic mutant rat.

Authors:  G Milhaud; M L Labat; M Parant; C Damais; L Chedid
Journal:  Proc Natl Acad Sci U S A       Date:  1977-01       Impact factor: 11.205

8.  Mitogenic effects of bacterial cell walls, their fragments, and related synthetic compounds on thymocytes and splenocytes of guinea pigs.

Authors:  H Takada; M Tsujimoto; S Kotani; S Kusumoto; M Inage; T Shiba; S Nagao; I Yano; S Kawata; K Yokogawa
Journal:  Infect Immun       Date:  1979-08       Impact factor: 3.441

9.  Suramin stimulates B-lymphocyte proliferation in the mouse.

Authors:  T L Vischer
Journal:  Agents Actions       Date:  1976-07

10.  Immunological activities of Capnocytophaga cellular components.

Authors:  Y Murayama; K Muranishi; H Okada; K Kato; S Kotani; H Takada; M Tsujimoto; A Kawasaki; T Ogawa
Journal:  Infect Immun       Date:  1982-06       Impact factor: 3.441
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