Literature DB >> 45087

[In vitro activity of cefaclor (author's transl)].

H Knothe.   

Abstract

A comparative study was conducted on the in vitro activity of cefaclor and other oral cephalosporins against a large number of freshly isolated clinical strains of gram-negative and gram-positive bacteria. The activity of cefaclor against gram-positive pathogens is very similar to that of cephalexin. The action of cefaclor against Streptococcus pneumoniae is superior. Cefaclor is the most active antibiotic against strains of Haemophilus influenzae, and is also more active than cephalexin and cephradine against non-beta-lactamase producing strains of Escherichia coli, Klebsiella species and Proteus mirabilis.

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Year:  1979        PMID: 45087     DOI: 10.1007/bf01659726

Source DB:  PubMed          Journal:  Infection        ISSN: 0300-8126            Impact factor:   3.553


  15 in total

1.  Comparative pharmacology of cefaclor and cephalexin.

Authors:  O M Korzeniowski; W M Scheld; M A Sande
Journal:  Antimicrob Agents Chemother       Date:  1977-08       Impact factor: 5.191

2.  Comparison of in vitro activity of cephalexin, cephradine, and cefaclor.

Authors:  N J Bill; J A Washington
Journal:  Antimicrob Agents Chemother       Date:  1977-03       Impact factor: 5.191

3.  Laoratory appraisal of cephalexin.

Authors:  P W Muggleton; C H O'Callaghan; R D Foord; S M Kirby; D M Ryan
Journal:  Antimicrob Agents Chemother (Bethesda)       Date:  1968

4.  In vitro susceptibility of Haemophilus influenzae to sulfamethoxazole-trimethoprim and cefaclor, cephalexin, and cephradine.

Authors:  R Sinai; S Hammerberg; M I Marks; C H Pai
Journal:  Antimicrob Agents Chemother       Date:  1978-05       Impact factor: 5.191

5.  Concentration relationships of cefaclor in serum, interstitial fluid, bile, and urine of dogs.

Authors:  N G Waterman; L F Scharfenberger
Journal:  Antimicrob Agents Chemother       Date:  1978-10       Impact factor: 5.191

6.  In vitro activities of five oral cephalosporins against aerobic pathogenic bacteria.

Authors:  S Shadomy; G Wagner; M Carver
Journal:  Antimicrob Agents Chemother       Date:  1977-11       Impact factor: 5.191

7.  In vitro studies with cefaclor, a new oral cephalosporin.

Authors:  C Sanders
Journal:  Antimicrob Agents Chemother       Date:  1977-10       Impact factor: 5.191

8.  Comparative beta-lactamase resistance and antistaphylococcal activities of parenterally and orally administered cephalosporins.

Authors:  W E Farrar; N M O'Dell
Journal:  J Infect Dis       Date:  1978-04       Impact factor: 5.226

9.  Cefaclor: in vitro spectrum of activity and beta-lactamase stability.

Authors:  H C Neu; K P Fu
Journal:  Antimicrob Agents Chemother       Date:  1978-04       Impact factor: 5.191

10.  Pharmacological evaluation of cefaclor in volunteers.

Authors:  G R Hodges; C Liu; D R Hinthorn; J L Harms; D L Dworzack
Journal:  Antimicrob Agents Chemother       Date:  1978-09       Impact factor: 5.191

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  1 in total

1.  In vitro activity of Ro 15-8074 and Ro 19-5247 in comparison to cefaclor and cefalexin.

Authors:  C Simon
Journal:  Infection       Date:  1987 Mar-Apr       Impact factor: 3.553

  1 in total

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