Literature DB >> 429008

Sister chromatid exchanges and aging. III. The effect of donor age on mutagen-induced sister chromatid exchange in human diploid fibroblasts.

E L Schneider, B Gilman.   

Abstract

Although baseline levels of SCE appear to be similar in metaphase cells derived from young and old human skin fibroblast cultures, a significant decline in both MMC- and AAAF-induced sister chromatid exchanges was observed in the older cell populations. Considerable variation exists in the levels of MMC-induced SCE between individual cell cultures. However, parallel examination of several cell strains from young and old donors confirmed the decrease in mutagen-induced SCE frequencies in older cell populations.

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Year:  1979        PMID： 429008     DOI： 10.1007/bf00278902

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  19 in total

1.  Sister chromatid exchanges--a sensitive assay of agents damaging human chromosomes.

Authors:  E Solomon; M Bobrow
Journal:  Mutat Res       Date:  1975-11       Impact factor: 2.433

2.  Induction by alkylating agents of sister chromatid exchanges and chromatid breaks in Fanconi's anemia.

Authors:  S A Latt; G Stetten; L A Juergens; G R Buchanan; P S Gerald
Journal:  Proc Natl Acad Sci U S A       Date:  1975-10       Impact factor: 11.205

3.  Rate of DNA repair in progeric and normal human fibroblasts.

Authors:  J Epstein; J R Williams; J B Little
Journal:  Biochem Biophys Res Commun       Date:  1974-08-05       Impact factor: 3.575

4.  Microfluorometric detection of deoxyribonucleic acid replication in human metaphase chromosomes.

Authors:  S A Latt
Journal:  Proc Natl Acad Sci U S A       Date:  1973-12       Impact factor: 11.205

5.  Aging and sister chromatid exchange. II. The effect of the in vitro passage level of human fetal lung fibroblasts on baseline and mutagen-induced sister chromatid exchange frequencies.

Authors:  E L Schneider; R E Monticone
Journal:  Exp Cell Res       Date:  1978-09       Impact factor: 3.905

6.  [Chromatid exchanges in human mitotic cells. BUDR Treatment and bichromatic fluorescence by aridine orange (author's transl)].

Authors:  B Dutrillauz; A M Fosse; M Prieur; J Lejeune
Journal:  Chromosoma       Date:  1974       Impact factor: 4.316

7.  Cytological detection of mutagen-carcinogen exposure by sister chromatid exchange.

Authors:  P Perry; H J Evans
Journal:  Nature       Date:  1975-11-13       Impact factor: 49.962

8.  DNA repair in late-passage human cells.

Authors:  R W Hart; R B Setlow
Journal:  Mech Ageing Dev       Date:  1976 Jan-Feb       Impact factor: 5.432

9.  Colony size distributions as a measure of in vivo and in vitro aging.

Authors:  J R Smith; O M Pereira-Smith; E L Schneider
Journal:  Proc Natl Acad Sci U S A       Date:  1978-03       Impact factor: 11.205

10.  The relationship between in vitro cellular aging and in vivo human age.

Authors:  E L Schneider; Y Mitsui
Journal:  Proc Natl Acad Sci U S A       Date:  1976-10       Impact factor: 11.205
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  10 in total

1.  Tissue-specific differences in the accumulation of sequence rearrangements with age.

Authors:  Dominika M Wiktor-Brown; Werner Olipitz; Carrie A Hendricks; Rebecca E Rugo; Bevin P Engelward
Journal:  DNA Repair (Amst)       Date:  2008-03-20

2.  A family study of spontaneous sister chromatid exchange frequency.

Authors:  M M Cohen; A O Martin; C Ober; S J Simpson
Journal:  Am J Hum Genet       Date:  1982-03       Impact factor: 11.025

Review 3.  Cell culture aging.

Authors:  M Reff; E L Schneider
Journal:  Mol Cell Biochem       Date:  1981-05-26       Impact factor: 3.396

Review 4.  Sister chromatid exchange analysis.

Authors:  S A Latt; R R Schreck
Journal:  Am J Hum Genet       Date:  1980-05       Impact factor: 11.025

5.  Sister chromatid exchange frequencies in Progeria and Werner syndrome patients.

Authors:  G J Darlington; R Dutkowski; W T Brown
Journal:  Am J Hum Genet       Date:  1981-09       Impact factor: 11.025

6.  Cytogenetics and cytokinetics of cultured lymphocytes from benzene-exposed workers.

Authors:  T Watanabe; A Endo; Y Kato; S Shima; T Watanabe; M Ikeda
Journal:  Int Arch Occup Environ Health       Date:  1980       Impact factor: 3.015

7.  Sister chromatid exchanges and structural chromosome aberrations in relation to age and sex.

Authors:  K Hedner; B Högstedt; A M Kolnig; E Mark-Vendel; B Strömbeck; F Mitelman
Journal:  Hum Genet       Date:  1982       Impact factor: 4.132

8.  Cyclophosphamide-induced in vivo sister chromatid exchanges (SCE) in Mus musculus. III. Quantitative genetic analysis.

Authors:  D L Reimer; S M Singh
Journal:  Genetics       Date:  1983-09       Impact factor: 4.562

9.  The effect of donor sex and age on the number of sister chromatid exchanges in human lymphocytes growing in vitro.

Authors:  M A de Arce
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132

10.  Variation in the sensitivity of human lymphocytes to DNA-damaging agents measured by sister chromatid exchange frequency.

Authors:  P E Crossen
Journal:  Hum Genet       Date:  1982       Impact factor: 4.132
  10 in total

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