Literature DB >> 7019665

Cell culture aging.

M Reff, E L Schneider.   

Abstract

Cellular research in aging has been stimulated by the observation that human diploid cells have a limited number of cell divisions in culture. This loss of cellular proliferation (in vitro senescence) has been extensively studied by biochemical, clonal, and genetic analysis. Studies of human skin fibroblast cultures have revealed that in vitro senescense is related to in vivo human cellular aging. Recently differentiated cells have been proposed for aging studies. These cells may provide additional information on aging since alterations of in vitro cellular functions may be related to the in vivo behavior of specific differented cell types.

Entities:  

Mesh：

Year:  1981        PMID： 7019665     DOI： 10.1007/bf02357034

Source DB:  PubMed          Journal:  Mol Cell Biochem        ISSN： 0300-8177            Impact factor:   3.396


  58 in total

1.  The maintenance of the accuracy of protein synthesis and its relevance to ageing.

Authors:  L E ORGEL
Journal:  Proc Natl Acad Sci U S A       Date:  1963-04       Impact factor: 11.205

2.  In vivo BUdR labeling of mammalian chromosomes.

Authors:  E L Schneider; J R Chaillet; R R Tice
Journal:  Exp Cell Res       Date:  1976-07       Impact factor: 3.905

3.  Long term culture of normal and neoplastic human glia.

Authors:  J Pontén; E H Macintyre
Journal:  Acta Pathol Microbiol Scand       Date:  1968

4.  Microfluorometric detection of deoxyribonucleic acid replication in human metaphase chromosomes.

Authors:  S A Latt
Journal:  Proc Natl Acad Sci U S A       Date:  1973-12       Impact factor: 11.205

5.  Attempted hybridizations with senescent human fibroblasts.

Authors:  J W Littlefield
Journal:  J Cell Physiol       Date:  1973-08       Impact factor: 6.384

6.  The sensitivity to hyperbaric oxygen of human diploid fibroblasts during ageing in vitro.

Authors:  S Honda; M Matsuo
Journal:  Mech Ageing Dev       Date:  1980-01       Impact factor: 5.432

7.  Pattern formation by cultured human epidermal cells: development of curved ridges resembling dermatoglyphs.

Authors:  H Green; J Thomas
Journal:  Science       Date:  1978-06-23       Impact factor: 47.728

8.  Effect of donor age on the binding and degradation of low density lipoproteins by cultured human arterial smooth muscle cells.

Authors:  E L Bierman; J J Albers; A Chait
Journal:  J Gerontol       Date:  1979-07

Review 9.  Progress in cytogerontology.

Authors:  L Hayflick
Journal:  Mech Ageing Dev       Date:  1979-03       Impact factor: 5.432

10.  The effect of donor age on the in vitro life span of cultured human arterial smooth-muscle cells.

Authors:  E L Bierman
Journal:  In Vitro       Date:  1978-11
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  3 in total

1.  Erythrocytes inhibit ligament fibroblast proliferation in a collagen scaffold.

Authors:  Sophia L Harrison; Patrick Vavken; Martha M Murray
Journal:  J Orthop Res       Date:  2011-03-28       Impact factor: 3.494

2.  Increased expression of the Hutchinson-Gilford progeria syndrome truncated lamin A transcript during cell aging.

Authors:  Sofia Rodriguez; Fabio Coppedè; Hanna Sagelius; Maria Eriksson
Journal:  Eur J Hum Genet       Date:  2009-01-28       Impact factor: 4.246

3.  The effect of skeletal maturity on the regenerative function of intrinsic ACL cells.

Authors:  Ashley N Mastrangelo; Elise M Magarian; Matthew P Palmer; Patrick Vavken; Martha M Murray
Journal:  J Orthop Res       Date:  2010-05       Impact factor: 3.494
  3 in total

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