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Literature DB >> 7166305

Sister chromatid exchanges and structural chromosome aberrations in relation to age and sex.

K Hedner, B Högstedt, A M Kolnig, E Mark-Vendel, B Strömbeck, F Mitelman.

Abstract

Sister chromatid exchanges (SCE) and structural chromosome aberrations were analyzed in peripheral blood lymphocytes of 100 individuals, and correlated to age and sex. No correlation was found between the frequency of SCE and age, but older individuals had significantly more structural aberrations than younger. Females had significantly more SCE as well as structural chromosome aberrations than males. The positive correlations of SCE and structural aberrations to age and sex were also significant when these factors, as well as smoking habits, were taken into consideration in an analysis of covariance.

Mesh：

Year: 1982 PMID： 7166305 DOI： 10.1007/bf00304544

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

27 in total

1. Sister chromatid exchanges in ageing and repair-deficient human fibroblasts.

Authors: H Kato; H F Stich
Journal: Nature Date: 1976-04-01 Impact factor: 49.962

2. Chromosomes in old age: a six year longitudinal study.

Authors: L F Jarvik; F S Yen; T K Fu; S S Matsuyama
Journal: Hum Genet Date: 1976-07-07 Impact factor: 4.132

3. Microfluorometric detection of deoxyribonucleic acid replication in human metaphase chromosomes.

Authors: S A Latt
Journal: Proc Natl Acad Sci U S A Date: 1973-12 Impact factor: 11.205

Review 4. Sister chromatid exchange (SCE) and structural chromosome aberration in mutagenicity testing.

Authors: E Gebhart
Journal: Hum Genet Date: 1981 Impact factor: 4.132

5. Differential Giemsa staining of sister chromatids and the study of chromatid exchanges without autoradiography.

Authors: S Wolff; P Perry
Journal: Chromosoma Date: 1974 Impact factor: 4.316

6. Total aneuploidy and age-related sex chromosome aneuploidy in cultured lymphocytes of normal men and women.

Authors: P H Fitzgerald; C M McEwan
Journal: Hum Genet Date: 1977-12-23 Impact factor: 4.132

7. Sister chromatid exchange in human chromosomes from normal individuals and patients with ataxia telangiectasia.

Authors: S M Galloway; H J Evans
Journal: Cytogenet Cell Genet Date: 1975

8. The effect of donor sex and age on the number of sister chromatid exchanges in human lymphocytes growing in vitro.

Authors: M A de Arce
Journal: Hum Genet Date: 1981 Impact factor: 4.132

9. The incidence of sister chromatid exchanges in cultured human lymphocytes.

Authors: W F Morgan; P E Crossen
Journal: Mutat Res Date: 1977-02 Impact factor: 2.433

10. Chromosome aberrations and sister-chromatid exchange in workers in chemical laboratories and a rotoprinting factory and in children of women laboratory workers.

Authors: F Funes-Cravioto; C Zapata-Gayon; B Kolmodin-Hedman; B Lambert; J Lindsten; E Norberg; M Nordenskjöld; R Olin; A Swensson
Journal: Lancet Date: 1977-08-13 Impact factor: 79.321

5 in total

4. Genotype-specific reduction in methyl nitrosourea (MNU) induced sister chromatid exchanges (SCE) in vivo during aging.

Authors: S L Bond; S M Singh
Journal: Experientia Date: 1988-09-15

5. Spontaneous and induced chromosomal instability in Werner syndrome.

Authors: E Gebhart; R Bauer; U Raub; M Schinzel; K W Ruprecht; J B Jonas
Journal: Hum Genet Date: 1988-10 Impact factor: 4.132