Literature DB >> 52847

Cytological detection of mutagen-carcinogen exposure by sister chromatid exchange.

P Perry, H J Evans.   

Abstract

A staining technique that detects sister chromatid exchanges (SCEs) has been used to examine the response of chromosomes in cultured Chinese hamster cells to a wide variety of mutagens-carcinogens. The test gives a very sensitive and rapid method for detecting chromosome mutagenicity of chemical agents and provides a powerful new method for detecting environmental mutagens.

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Year:  1975        PMID： 52847     DOI： 10.1038/258121a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  182 in total

1.  X-irradiation of G1 CHO cells induces SCE which are both true and false in BrdU-substituted cells but only false in biotin-dUTP-substituted cells.

Authors:  E Bruckmann; A Wojcik; G Obe
Journal:  Chromosome Res       Date:  1999       Impact factor: 5.239

2.  Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells.

Authors:  R D Johnson; M Jasin
Journal:  EMBO J       Date:  2000-07-03       Impact factor: 11.598

3.  Sister chromatid exchanges in human lymphocytes exposed to 8-methoxypsoralen and long wave UV radiation prior to incorporation of bromodeoxyuridine.

Authors:  D Mourelatos; M J Faed; B E Johnson
Journal:  Experientia       Date:  1977-08-15

4.  Sister chromatid exchange in patients treated with nonsteroidal anti-inflammatory drugs.

Authors:  S Sardaş; A E Karakaya; N Uğur; M Cengel; A Metin
Journal:  Drug Saf       Date:  1991 Sep-Oct       Impact factor: 5.606

5.  Induction of the fragile X on BrdU-substituted chromosomes with direct visualization of sister chromatid exchanges on banded chromosomes.

Authors:  N Tommerup
Journal:  Hum Genet       Date:  1989-03       Impact factor: 4.132

6.  Search for DNA interchange corresponding to sister chromatid exchanges in Chinese hamster ovary cells.

Authors:  K S Loveday; S A Latt
Journal:  Nucleic Acids Res       Date:  1978-11       Impact factor: 16.971

7.  Strand breaks arising from the repair of the 5-bromodeoxyuridine-substituted template and methyl methanesulphonate-induced lesions can explain the formation of sister chromatid exchanges.

Authors:  R Saffhill; C H Ockey
Journal:  Chromosoma       Date:  1985       Impact factor: 4.316

8.  Chromosome studies on lymphocytes of patients under cytostatic therapy. II. Studies Using the BUDR-labelling technique in cytostatic interval therapy.

Authors:  E Gebhart; B Windolph; F Wopfner
Journal:  Hum Genet       Date:  1980       Impact factor: 4.132

Review 9.  Relationship of chromosome changes to neoplastic cell transformation.

Authors:  J A DiPaolo; N C Popescu
Journal:  Am J Pathol       Date:  1976-12       Impact factor: 4.307

10.  Replication bypass model of sister chromatid exchanges and implications for Bloom's syndrome and Fanconi's anemia.

Authors:  D A Shafer
Journal:  Hum Genet       Date:  1977-11-10       Impact factor: 4.132
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