Literature DB >> 4288238

Heat-labile serum factor required for immunofluorescence of polyoma tumor antigens.

K K Takemoto, R A Malmgren, K Habel.   

Abstract

The immunofluorescent demonstration of polyoma tumor antigens in tumor cells requires a heatlabile serum component. With unheated hamster tumor serum, specific fluorescence was observed in polyoma-transformed hamster, mouse, and rat tumor cells. Heated serum usually gave little or no reactivity; the activity of such heated serum could be restored simply by the addition of fresh normal unheated hamster serum.

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Year:  1966        PMID： 4288238     DOI： 10.1126/science.153.3740.1122

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  10 in total

1.  Multiple forms of polyoma virus tumor antigens from infected and transformed cells.

Authors:  D T Simmons; C Chang; M A Martin
Journal:  J Virol       Date:  1979-03       Impact factor: 5.103

2.  Properties of hybrids between polyoma-transformed and normal mouse cells.

Authors:  V Defendi; B Ephrussi; H Koprowski; M C Yoshida
Journal:  Proc Natl Acad Sci U S A       Date:  1967-02       Impact factor: 11.205

3.  Multicopy plasmid with a structure related to the polyoma virus genome.

Authors:  T Kusano; H Uehara; H Saito; K Segawa; M Oishi
Journal:  Proc Natl Acad Sci U S A       Date:  1987-04       Impact factor: 11.205

Review 4.  Somatic cell hybridization and problems of viral oncogenesis.

Authors:  G Marin
Journal:  In Vitro       Date:  1970

5.  Analysis of hamster tumor cell lines isolated from single colonies soon after induction by polyoma strains differing in transplant antigen production.

Authors:  J D Hare
Journal:  J Virol       Date:  1967-10       Impact factor: 5.103

6.  Lack of oncogenic potential of measles virus on Syrian hamster embryo cell cultures.

Authors:  G T Diamandopoulos
Journal:  J Virol       Date:  1968-05       Impact factor: 5.103

7.  Middle tumor antigen of polyomavirus transformation-defective mutant NG59 is associated with pp60c-src.

Authors:  J B Bolen; M A Israel
Journal:  J Virol       Date:  1985-01       Impact factor: 5.103

8.  Large T antigens of many polyomaviruses are able to form complexes with the retinoblastoma protein.

Authors:  N Dyson; R Bernards; S H Friend; L R Gooding; J A Hassell; E O Major; J M Pipas; T Vandyke; E Harlow
Journal:  J Virol       Date:  1990-03       Impact factor: 5.103

9.  Interrupting the early region of polyoma virus DNA enhances tumorigenicity.

Authors:  M A Israel; D T Simmons; S L Hourihan; W P Rowe; M A Martin
Journal:  Proc Natl Acad Sci U S A       Date:  1979-08       Impact factor: 11.205

10.  Tyrosine phosphorylation within the amino-terminal domain of pp60c-src molecules associated with polyoma virus middle-sized tumor antigen.

Authors:  W Yonemoto; M Jarvis-Morar; J S Brugge; J B Bolen; M A Israel
Journal:  Proc Natl Acad Sci U S A       Date:  1985-07       Impact factor: 11.205
  10 in total

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