Literature DB >> 2154613

Large T antigens of many polyomaviruses are able to form complexes with the retinoblastoma protein.

N Dyson1, R Bernards, S H Friend, L R Gooding, J A Hassell, E O Major, J M Pipas, T Vandyke, E Harlow.   

Abstract

Stable protein complexes between the large T antigens of mouse, monkey, baboon, or human polyomaviruses and the retinoblastoma protein were detected by an in vitro coimmunoprecipitation assay. All of the large T antigens tested were able to bind to both human and mouse retinoblastoma polypeptides, showing that these interactions have been conserved during evolution.

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Year:  1990        PMID: 2154613      PMCID: PMC249255          DOI: 10.1128/JVI.64.3.1353-1356.1990

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  41 in total

1.  Cellular targets for transformation by the adenovirus E1A proteins.

Authors:  P Whyte; N M Williamson; E Harlow
Journal:  Cell       Date:  1989-01-13       Impact factor: 41.582

2.  The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus.

Authors:  N Dyson; K Buchkovich; P Whyte; E Harlow
Journal:  Cell       Date:  1989-07-28       Impact factor: 41.582

3.  The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element.

Authors:  J A DeCaprio; J W Ludlow; D Lynch; Y Furukawa; J Griffin; H Piwnica-Worms; C M Huang; D M Livingston
Journal:  Cell       Date:  1989-09-22       Impact factor: 41.582

4.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

5.  Adenovirus E1a ras cooperation activity is separate from its positive and negative transcription regulatory functions.

Authors:  A Velcich; E Ziff
Journal:  Mol Cell Biol       Date:  1988-05       Impact factor: 4.272

6.  Sequences in E1A proteins of human adenovirus 5 required for cell transformation, repression of a transcriptional enhancer, and induction of proliferating cell nuclear antigen.

Authors:  T N Jelsma; J A Howe; J S Mymryk; C M Evelegh; N F Cunniff; S T Bayley
Journal:  Virology       Date:  1989-07       Impact factor: 3.616

7.  A point mutational analysis of human papillomavirus type 16 E7 protein.

Authors:  C Edmonds; K H Vousden
Journal:  J Virol       Date:  1989-06       Impact factor: 5.103

8.  Heat-labile serum factor required for immunofluorescence of polyoma tumor antigens.

Authors:  K K Takemoto; R A Malmgren; K Habel
Journal:  Science       Date:  1966-09-02       Impact factor: 47.728

9.  An N-terminal transformation-governing sequence of SV40 large T antigen contributes to the binding of both p110Rb and a second cellular protein, p120.

Authors:  M E Ewen; J W Ludlow; E Marsilio; J A DeCaprio; R C Millikan; S H Cheng; E Paucha; D M Livingston
Journal:  Cell       Date:  1989-07-28       Impact factor: 41.582

10.  Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product.

Authors:  K Münger; B A Werness; N Dyson; W C Phelps; E Harlow; P M Howley
Journal:  EMBO J       Date:  1989-12-20       Impact factor: 11.598

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  103 in total

1.  J domain-independent regulation of the Rb family by polyomavirus large T antigen.

Authors:  Q Sheng; T M Love; B Schaffhausen
Journal:  J Virol       Date:  2000-06       Impact factor: 5.103

2.  Mutagenesis of the pRB pocket reveals that cell cycle arrest functions are separable from binding to viral oncoproteins.

Authors:  F A Dick; E Sailhamer; N J Dyson
Journal:  Mol Cell Biol       Date:  2000-05       Impact factor: 4.272

3.  The molecular chaperone activity of simian virus 40 large T antigen is required to disrupt Rb-E2F family complexes by an ATP-dependent mechanism.

Authors:  C S Sullivan; P Cantalupo; J M Pipas
Journal:  Mol Cell Biol       Date:  2000-09       Impact factor: 4.272

Review 4.  Structure and function of JC virus T' proteins.

Authors:  R J Frisque
Journal:  J Neurovirol       Date:  2001-08       Impact factor: 2.643

5.  Loss of p19(ARF) eliminates the requirement for the pRB-binding motif in simian virus 40 large T antigen-mediated transformation.

Authors:  H H Chao; A M Buchmann; J A DeCaprio
Journal:  Mol Cell Biol       Date:  2000-10       Impact factor: 4.272

Review 6.  Brain tumors and polyomaviruses.

Authors:  Sidney Croul; Jessica Otte; Kamel Khalili
Journal:  J Neurovirol       Date:  2003-04       Impact factor: 2.643

7.  Homologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteins.

Authors:  N Dyson; P Guida; K Münger; E Harlow
Journal:  J Virol       Date:  1992-12       Impact factor: 5.103

8.  Simian virus 40 infection of humans.

Authors:  Robert L Garcea; Michael J Imperiale
Journal:  J Virol       Date:  2003-05       Impact factor: 5.103

9.  Dissecting the contribution of p16(INK4A) and the Rb family to the Ras transformed phenotype.

Authors:  Philip J Mitchell; Elena Perez-Nadales; Denise S Malcolm; Alison C Lloyd
Journal:  Mol Cell Biol       Date:  2003-04       Impact factor: 4.272

10.  Mutation of a cysteine residue in polyomavirus middle T antigen abolishes interactions with protein phosphatase 2A, pp60c-src, and phosphatidylinositol-3 kinase, activation of c-fos expression, and cellular transformation.

Authors:  G M Glenn; W Eckhart
Journal:  J Virol       Date:  1993-04       Impact factor: 5.103

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