Literature DB >> 3023831

Liver-specific expression of a Qa-encoded class I gene is associated with DNA hypomethylation.

C G Miyada, R B Wallace.   

Abstract

DNA methylation of two murine major histocompatibility complex (H-2) class I genes was examined in hybridizations to MspI and HpaII chromosomal DNA restriction digests. Q10, which exhibits liver-specific expression, and H-2Kb, a transplantation antigen gene, were examined in liver, spleen, thymus, and cell-line DNAs. Unmethylated Q10 gene sequences were detected only in the liver, whereas the H-2Kb gene was unmethylated in all tissues examined.

Entities:  

Mesh：

Substances：

Year:  1986        PMID： 3023831      PMCID： PMC367512          DOI： 10.1128/mcb.6.1.315-317.1986

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  19 in total

Review 1.  Morphologic aspects of hepatic synthesis and secretion of plasma proteins.

Authors:  G Feldmann
Journal:  Prog Liver Dis       Date:  1979

Review 2.  Genes of the major histocompatibility complex of the mouse.

Authors:  L Hood; M Steinmetz; B Malissen
Journal:  Annu Rev Immunol       Date:  1983       Impact factor: 28.527

3.  Hybridization of nucleic acids directly in agarose gels.

Authors:  S G Tsao; C F Brunk; R E Pearlman
Journal:  Anal Biochem       Date:  1983-06       Impact factor: 3.365

Review 4.  DNA methylation and gene function.

Authors:  A Razin; A D Riggs
Journal:  Science       Date:  1980-11-07       Impact factor: 47.728

5.  Clusters of genes encoding mouse transplantation antigens.

Authors:  M Steinmetz; A Winoto; K Minard; L Hood
Journal:  Cell       Date:  1982-03       Impact factor: 41.582

6.  Secretion of a transplantation-related antigen.

Authors:  M Kress; D Cosman; G Khoury; G Jay
Journal:  Cell       Date:  1983-08       Impact factor: 41.582

Review 7.  The traditional and a new version of the mouse H-2 complex.

Authors:  J Klein; A Juretic; C N Baxevanis; Z A Nagy
Journal:  Nature       Date:  1981-06-11       Impact factor: 49.962

8.  Identification of the cloned gene for the murine transplantation antigen H-2Kb by hybridization with synthetic oligonucleotides.

Authors:  D H Schulze; L R Pease; Y Obata; S G Nathenson; A A Reyes; S Ikuta; R B Wallace
Journal:  Mol Cell Biol       Date:  1983-04       Impact factor: 4.272

9.  Methylation of mouse liver DNA studied by means of the restriction enzymes msp I and hpa II.

Authors:  J Singer; J Roberts-Ems; A D Riggs
Journal:  Science       Date:  1979-03-09       Impact factor: 47.728

10.  The DNA sequence of the H-2kb gene: evidence for gene conversion as a mechanism for the generation of polymorphism in histocompatibilty antigens.

Authors:  E Weiss; L Golden; R Zakut; A Mellor; K Fahrner; S Kvist; R A Flavell
Journal:  EMBO J       Date:  1983       Impact factor: 11.598
View more
  2 in total

1.  Expression of TL, H-2, and chimeric H-2/TL genes in transgenic mice: abnormal thymic differentiation and T-cell lymphomas in a TL transgenic strain.

Authors:  N Hamasima; T Takahashi; O Taguchi; Y Nishizuka; E Stockert; L J Old; Y Obata
Journal:  Proc Natl Acad Sci U S A       Date:  1989-10       Impact factor: 11.205

2.  Developmental and tissue-specific regulation of the Q10 class I gene by DNA methylation.

Authors:  K Tanaka; Y Barra; K J Isselbacher; G Khoury; G Jay
Journal:  Proc Natl Acad Sci U S A       Date:  1986-10       Impact factor: 11.205
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.