Literature DB >> 4215083

Organization of immunoglobulin genes: reiteration frequency of the mouse kappa chain constant region gene.

T Honjo, S Packman, D Swan, M Nau, P Leder.   

Abstract

Hybridization kinetic analyses with synthetic DNA indicate that there are only two to three copies of the kappa constant region gene per haploid genome. This result lends weight to the argument that the immunoglobulin light chain is encoded by more than one continuous gene sequence.

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Year:  1974        PMID： 4215083      PMCID： PMC433835          DOI： 10.1073/pnas.71.9.3659

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  53 in total

1.  Molecular weight determination of nucleic acids by gel electrophoresis in non-aqueous solution.

Authors:  D Z Staynov; J C Pinder; W B Gratzer
Journal:  Nat New Biol       Date:  1972-01-26

Review 2.  Antibody variability. Somatic recombination between the elements of "antibody gene pairs" may explain antibody variability.

Authors:  O Smithies
Journal:  Science       Date:  1967-07-21       Impact factor: 47.728

3.  Mechanism of antibody synthesis: size differences between mouse kappa chains.

Authors:  W R Gray; W J Dreyer; L Hood
Journal:  Science       Date:  1967-01-27       Impact factor: 47.728

4.  The molecular basis of antibody formation: a paradox.

Authors:  W J Dreyer; J C Bennett
Journal:  Proc Natl Acad Sci U S A       Date:  1965-09       Impact factor: 11.205

5.  Characterization of synthetic rabbit globin DNA.

Authors:  J Ross; H Aviv; P Leder
Journal:  Arch Biochem Biophys       Date:  1973-10       Impact factor: 4.013

6.  A "Lepore" type of hybrid gamma-globulin.

Authors:  H G Kunkel; J B Natvig; F G Joslin
Journal:  Proc Natl Acad Sci U S A       Date:  1969-01       Impact factor: 11.205

7.  A comparison of globin genes in duck reticulocytes and liver cells.

Authors:  S Packman; H Aviv; J Ross; P Leder
Journal:  Biochem Biophys Res Commun       Date:  1972-11-01       Impact factor: 3.575

8.  Distribution of allotypic specificities A1, A2, A14, and A15 among immunoglobulin G molecules.

Authors:  S L Tosi; S Dubiski; R G Mage
Journal:  J Immunol       Date:  1970-03       Impact factor: 5.422

9.  Genetic control of variable and constant regions of immunoglobulin heavy chains.

Authors:  R G Mage; G O Young-Cooper; C Alexander
Journal:  Nat New Biol       Date:  1971-03-10

10.  Origin of antibody variation.

Authors:  S Brenner; C Milstein
Journal:  Nature       Date:  1966-07-16       Impact factor: 49.962
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  19 in total

1.  Use of molecular hybridization to purify and analyze albumin messenger RNA from rat liver.

Authors:  R K Strair; S H Yap; D A Shafritz
Journal:  Proc Natl Acad Sci U S A       Date:  1977-10       Impact factor: 11.205

2.  Multiple related immunoglobulin variable-region genes identified by cloning and sequence analysis.

Authors:  J G Seidman; A Leder; M H Edgell; F Polsky; S M Tilghman; D C Tiemeier; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1978-08       Impact factor: 11.205

3.  Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions.

Authors:  N Hozumi; S Tonegawa
Journal:  Proc Natl Acad Sci U S A       Date:  1976-10       Impact factor: 11.205

4.  Transcription in vitro of immunoglobulin kappa light chain genes in isolated mouse myeloma nuclei and chromatin.

Authors:  M M Smith; R C Huang
Journal:  Proc Natl Acad Sci U S A       Date:  1976-03       Impact factor: 11.205

5.  Size differences among immunoglobulin heavy chains from phosphorylcholine-binding proteins.

Authors:  S Rudikoff; M Potter
Journal:  Proc Natl Acad Sci U S A       Date:  1976-06       Impact factor: 11.205

6.  Reiteration frequency of immunoglobulin light chain genes: further evidence for somatic generation of antibody diversity.

Authors:  S Tonegawa
Journal:  Proc Natl Acad Sci U S A       Date:  1976-01       Impact factor: 11.205

7.  No detectable reiteration of genes coding for mouse MOPC 41 immunoglobulin light-chain mRNA.

Authors:  M G Farace; M F Aellen; P A Briand; C H Faust; P Vassalli; B Mach
Journal:  Proc Natl Acad Sci U S A       Date:  1976-03       Impact factor: 11.205

8.  Nucleotide sequence of the thymidine kinase gene of herpes simplex virus type 1.

Authors:  M J Wagner; J A Sharp; W C Summers
Journal:  Proc Natl Acad Sci U S A       Date:  1981-03       Impact factor: 11.205

9.  Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switch.

Authors:  T Kataoka; T Kawakami; N Takahashi; T Honjo
Journal:  Proc Natl Acad Sci U S A       Date:  1980-02       Impact factor: 11.205

10.  Constancy of amino-terminal amino-acid sequences of antibodies of defined specificity and shared idiotype from individual inbred mice.

Authors:  B Friedenson; A S Tung; A Nisonoff
Journal:  Proc Natl Acad Sci U S A       Date:  1975-09       Impact factor: 11.205
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