Literature DB >> 4139713

Assignment of the human gene for hexose-1-phosphate uridylyltransferase to chromosome 3.

T A Tedesco, R Diamond, K G Orkwiszewski, H J Boedecker, C M Croce.   

Abstract

Mouse-human hybrid clones were tested for the presence of human hexose-1-phosphate uridylyl-transferase (EC 2.7.7.12;UDPglucose:alpha-D-galactose-1-phosphate uridylyltransferase). Two criteria, starch gel electrophoresis and double-immunodiffusion against a human transferase-specific antibody, were used to identify human enzyme in the hybrid clones. Seventeen of 33 hybrid clones analyzed were found to contain human transferase by both criteria. Karyological analysis of the hybrid clones showed concordant segregation of human transferase with human chromosome 3. Human galactokinase was asyntenic with human transferase. We thus assign this gene to human chromosome 3.

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Year:  1974        PMID： 4139713      PMCID： PMC433798          DOI： 10.1073/pnas.71.9.3483

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  12 in total

1.  Preferential retention of the human chromosome C-7 in human-(thymidine kinase deficient) mouse hybrid cells.

Authors:  C M Croce; B B Knowles; H Koprowski
Journal:  Exp Cell Res       Date:  1973-12       Impact factor: 3.905

2.  Linkage analysis in man by somatic cell genetics.

Authors:  F H Ruddle
Journal:  Nature       Date:  1973-03-16       Impact factor: 49.962

3.  Human galactose 1-phosphate uridyltransferase. Purification, antibody production, and comparison of the wild type, Duarte variant, and galactosemic gene products.

Authors:  T A Tedesco
Journal:  J Biol Chem       Date:  1972-10-25       Impact factor: 5.157

4.  Purification and properties of galactokinase from human red blood cells.

Authors:  K G Blume; E Beutler
Journal:  J Biol Chem       Date:  1971-11       Impact factor: 5.157

5.  Assignment of the T-antigen gene of simian virus 40 to human chromosome C-7.

Authors:  C M Croce; A J Girardi; H Koprowski
Journal:  Proc Natl Acad Sci U S A       Date:  1973-12       Impact factor: 11.205

6.  Tay-Sachs disease: generalized absence of a beta-D-N-acetylhexosaminidase component.

Authors:  S Okada; J S O'Brien
Journal:  Science       Date:  1969-08-15       Impact factor: 47.728

7.  Loss of human genetic markers in man--Chinese hamster somatic cell hybrids.

Authors:  A Westerveld; R P Visser; P Meera Khan; D Bootsma
Journal:  Nat New Biol       Date:  1971-11-03

8.  Human regulatory gene for inducible tyrosine aminotransferase in rat-human hybrids.

Authors:  C M Croce; G Litwack; H Koprowski
Journal:  Proc Natl Acad Sci U S A       Date:  1973-04       Impact factor: 11.205

9.  Human-mouse hybrid cell lines containing partial complements of human chromosomes and functioning human genes.

Authors:  M C Weiss; H Green
Journal:  Proc Natl Acad Sci U S A       Date:  1967-09       Impact factor: 11.205

10.  Galactose-1-phosphate uridyltransferase and galactokinase activity in cultured human diploid fibroblasts and peripheral blood leukocytes. I. Analysis of transferase genotypes by the ratio of the activities of the two enzymes.

Authors:  T A Tedesco; W J Mellman
Journal:  J Clin Invest       Date:  1969-12       Impact factor: 14.808
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  13 in total

1.  Regional chromosomal localization of the human gene for galactose-1-phosphate uridyltransferase.

Authors:  N C Sun; C R Sun; E H Chu
Journal:  Hum Genet       Date:  1977-07-26       Impact factor: 4.132

2.  Expression of alpha-D-mannosidase in man-hamster somatic cell hybrids.

Authors:  P H Ingram; G A Bruns; V M Regina; R E Eisenman; P S Gerald
Journal:  Biochem Genet       Date:  1977-06       Impact factor: 1.890

3.  An immunochemical method for the detection of the expression of human gene loci in human-rodent somatic cell hybrids with special reference to the GPI locus.

Authors:  H R Palser; P J McAlpine
Journal:  Biochem Genet       Date:  1976-08       Impact factor: 1.890

4.  Where is the gene for GALT?

Authors:  M T Mulcahy; R G Wilson
Journal:  Hum Genet       Date:  1980       Impact factor: 4.132

5.  Aconitase (E.C. 4.2.1.3) mitochondrial locus mapped to human chromosome 22: studies with Chinese hamster--human somatic cell hybrids.

Authors:  R S Sparkes; T Mohandas; M C Sparkes; J D Shulkin
Journal:  Biochem Genet       Date:  1978-08       Impact factor: 1.890

6.  Regional localization of human gene loci on chromosome 9: studies of somatic cell hybrids containing human translocations.

Authors:  T Mohandas; R S Sparkes; M C Sparkes; J D Shulkin; K E Toomey; S J Funderburk
Journal:  Am J Hum Genet       Date:  1979-09       Impact factor: 11.025

7.  The Philadelphia variant of galactokinase.

Authors:  T A Tedesco; K L Miller; B E Rawnsley; M C Adams; H B Markus; K G Orkwiszewski; W J Mellman
Journal:  Am J Hum Genet       Date:  1977-05       Impact factor: 11.025

8.  Probable linkage between the human galactose-1-P uridyl transferase locus and 9qh.

Authors:  R S Sparkes; P A Epstein; K K Kidd; I Klisak; M C Sparkes; M Crist; L A Morton
Journal:  Am J Hum Genet       Date:  1980-03       Impact factor: 11.025

9.  A case of trisomy 3q21 leads to qter syndrome.

Authors:  I Kondo; T Hirano; H Hamaguchi; Y Ohta; S Haibara; H Nakai; H Takita
Journal:  Hum Genet       Date:  1979-01-25       Impact factor: 4.132

10.  Assignment of the human gene for galactose-1-phosphate uridyltransferase to chromosome 9: studies with Chinese hamster-human somatic cell hybrids.

Authors:  T Mohandas; R S Sparkes; M C Sparkes; J D Shulkin
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205
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