Literature DB >> 825107

An immunochemical method for the detection of the expression of human gene loci in human-rodent somatic cell hybrids with special reference to the GPI locus.

H R Palser, P J McAlpine.   

Abstract

Species-specific antibodies, prepared against unpurified human enzymes in human-hamster somatic cell hybrids. Results of the detection of the expression of the human glucosephosphate isomerase gene locus (GPI) by electrophoretic and immunochemical techniques were concordant in 17 instances. The human GPI synthesized by fibroblasts derived from skin explants and by somatic cell hybrids retaining the human GPI locus, regardless of whether the human parental cells were lymphocytes or fibroblasts, appeared to be antigenically identical.

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Year:  1976        PMID： 825107     DOI： 10.1007/BF00485844

Source DB:  PubMed          Journal:  Biochem Genet        ISSN： 0006-2928            Impact factor:   1.890


  13 in total

1.  Isoenzyme differences between a human diploid cell line, WI-38, and SV40-transformed WI-38.

Authors:  E M Bartholomew; W R Bartholomew; N R Rose
Journal:  J Immunol       Date:  1969-10       Impact factor: 5.422

2.  The association of glucose phasphate isomerase expression with human chromosome 19 using somatic cell hybrids.

Authors:  J L Hamerton; G R Douglas; P A Gee; B J Richardson
Journal:  Cytogenet Cell Genet       Date:  1973

3.  Genetic control of mitochondrial enzymes in human-mouse somatic cell hybrids.

Authors:  V Van Heyningen; I Craig; W Bodmer
Journal:  Nature       Date:  1973-04-20       Impact factor: 49.962

4.  Inherited variations in human phosphohexose isomerase.

Authors:  J C Detter; P O Ways; E R Giblett; M A Baughan; D A Hopkinson; S Povey; H Harris
Journal:  Ann Hum Genet       Date:  1968-05       Impact factor: 1.670

5.  Hybrids between human leukocytes and a mouse cell line: production and characterization.

Authors:  V Miggiano; M Nabholz; W Bodmer
Journal:  Wistar Inst Symp Monogr       Date:  1969

6.  Inherited variants of human nucleoside phosphorylase.

Authors:  Y H Edwards; D A Hopkinson; H Harris
Journal:  Ann Hum Genet       Date:  1971-05       Impact factor: 1.670

7.  Human red cell peptidases.

Authors:  W H Lewis; H Harris
Journal:  Nature       Date:  1967-07-22       Impact factor: 49.962

8.  Human beta-D-N-acetylhexosaminidases A and B: expression and linkage relationships in somatic cell hybrids.

Authors:  P A Lalley; M C Rattazzi; T B Shows
Journal:  Proc Natl Acad Sci U S A       Date:  1974-04       Impact factor: 11.205

9.  Assignment of the human gene for hexose-1-phosphate uridylyltransferase to chromosome 3.

Authors:  T A Tedesco; R Diamond; K G Orkwiszewski; H J Boedecker; C M Croce
Journal:  Proc Natl Acad Sci U S A       Date:  1974-09       Impact factor: 11.205

10.  Human-mouse hybrid cell lines containing partial complements of human chromosomes and functioning human genes.

Authors:  M C Weiss; H Green
Journal:  Proc Natl Acad Sci U S A       Date:  1967-09       Impact factor: 11.205
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  1 in total

1.  A new immunochemical method for the quantitative measurement of specific gene products in man-rodent somatic cell hybrids.

Authors:  P G de Groot; M N Hamers; A Westerveld; A W Schram; P Meera Khan; J M Tager
Journal:  Hum Genet       Date:  1978-11-16       Impact factor: 4.132
  1 in total

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