Literature DB >> 4120289

The relationship between 2 -microglobulin and immunoglobulin in cultured human lymphoid cell lines.

T H Hütteroth, H Cleve, S D Litwin, M D Poulik.   

Abstract

beta(2)-microglobulin was detected on the cell surface and in the medium of human lymphoid cells established in long-term culture. The secretion of beta(2)-microglobulin was relatively uniform when different cell lines were compared, whereas IgG production varied widely. kappa- and micro-membrane antigens were modulated by specific antibody; beta(2)-microglobulin was not modulated. Anti-kappa and anti-micro antisera had no effect on the expression of membrane beta(2)-microglobulin, nor had anti-beta(2)-microglobulin antiserum any effect on the expression of kappa- and micro-membrane antigens.

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Year:  1973        PMID: 4120289      PMCID: PMC2139389          DOI: 10.1084/jem.137.3.838

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  6 in total

1.  Synthesis of 2 -microglobulin by stimulated lymphocytes.

Authors:  G M Bernier; M W Fanger
Journal:  J Immunol       Date:  1972-08       Impact factor: 5.422

2.  Cultured lymphoid cell lines from normal subjects: membrane associated immunoglobulins studied by the mixed antiglobulin reaction.

Authors:  T H Hütteroth; S D Litwin; H Cleve
Journal:  Cell Immunol       Date:  1972-11       Impact factor: 4.868

3.  Isolation of an 2 -globulin characteristic of tubular proteinuria.

Authors:  J Cejka; M D Poulik
Journal:  Arch Biochem Biophys       Date:  1971-06       Impact factor: 4.013

4.  Immunoglobulin determinants on the lymphocytes of normal rabbits. I. Demonstration by the mixed antiglobulin reaction of determinants recognized by anti-gamma, anti-mu, anti-Fab and anti-allotype sera, anti-As4 and anti-As6.

Authors:  R R Coombs; B W Gurner; C A Janeway; A B Wilson; P G Gell; A S Kelus
Journal:  Immunology       Date:  1970-03       Impact factor: 7.397

5.  2 -Microglobulin--a free immunoglobulin domain.

Authors:  P A Peterson; B A Cunningham; I Berggård; G M Edelman
Journal:  Proc Natl Acad Sci U S A       Date:  1972-07       Impact factor: 11.205

6.  Initiation of protein synthesis at an unusual position in an immunoglobulin gene?

Authors:  O Smithies; M D Poulik
Journal:  Science       Date:  1972-01-14       Impact factor: 47.728

  6 in total
  12 in total

1.  The lymphocyte plasma membrane: locus of control in the immune response.

Authors:  L M Jerry; A K Sullivan
Journal:  In Vitro       Date:  1976-03

2.  Feto-specific features of human beta2-microglobulin.

Authors:  J Cejka; K Kithier; J Belamaric; M al-Sarraf
Journal:  Experientia       Date:  1974-05-15

3.  Serum beta 2-microglobulin and other "tumor associated" antigens in patients with bronchogenic carcinoma.

Authors:  C Mordasini; W Riesen; A Morell
Journal:  Lung       Date:  1982       Impact factor: 2.584

4.  beta 2-Microglobulin secretion from lymphoid cells: a study at the cellular level.

Authors:  L Hammarström; C I Smith
Journal:  Med Microbiol Immunol       Date:  1985       Impact factor: 3.402

5.  Multiple common properties of human beta2-microglobulin and the common portion fragment derived from HL-A antigen molecules.

Authors:  K Nakamuro; N Tanigaki; D Pressman
Journal:  Proc Natl Acad Sci U S A       Date:  1973-10       Impact factor: 11.205

6.  Highly purified papain-solubilized HL-A antigens contain beta2-microglobulin.

Authors:  P A Peterson; L Rask; J B Lindblom
Journal:  Proc Natl Acad Sci U S A       Date:  1974-01       Impact factor: 11.205

7.  Synovial fluid beta 2 microglobulin and hydroxyproline fractions in rheumatoid arthritis and nonautoimmune arthropathies.

Authors:  D Manicourt; H Brauman; S Orloff
Journal:  Ann Rheum Dis       Date:  1980-06       Impact factor: 19.103

8.  Tissue distribution of human alpha1-microglobulin.

Authors:  K Takagi; K Kin; Y Itoh; T Kawai; T Kasahara; T Shimoda; T Shikata
Journal:  J Clin Invest       Date:  1979-02       Impact factor: 14.808

9.  beta2-Microglobulin production by highly purified human T and B lymphocytes in cell culture stimulated with various mitogens.

Authors:  K Kin; T Kasahara; Y Itoh; I Sakurabayashi; T Kawai; M Morita
Journal:  Immunology       Date:  1979-01       Impact factor: 7.397

10.  Crystallographic studies of bovine beta2-microglobulin.

Authors:  J W Becker; J A Ziffer; G M Edelman; B A Cunningham
Journal:  Proc Natl Acad Sci U S A       Date:  1977-08       Impact factor: 11.205

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