Literature DB >> 5008437

Initiation of protein synthesis at an unusual position in an immunoglobulin gene?

O Smithies, M D Poulik.   

Abstract

The amino acid sequence of urinary beta(2)-microglobulin has been partially determined and found to be related to the constant region of IgG immunoglobulin heavy chain. beta(2)-Microglobulin is present in normal individuals. Its gene may have evolved from an immunoglobulin gene by the use of an unusually located start signal for initiating synthesis of the polypeptide.

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Year:  1972        PMID： 5008437     DOI： 10.1126/science.175.4018.187

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  38 in total

1.  Structure of HLA antigens: amino-acid and carbohydrate compositions and NH2-terminal sequences of four antigen preparations.

Authors:  C Terhorst; P Parham; D L Mann; J L Strominger
Journal:  Proc Natl Acad Sci U S A       Date:  1976-03       Impact factor: 11.205

2.  Evolutionary relationship between immunoglobulins and transplantation antigens.

Authors:  P A Peterson; L Rask; K Sege; L Klareskog; H Anundi; L Ostberg
Journal:  Proc Natl Acad Sci U S A       Date:  1975-04       Impact factor: 11.205

3.  The lymphocyte plasma membrane: locus of control in the immune response.

Authors:  L M Jerry; A K Sullivan
Journal:  In Vitro       Date:  1976-03

4.  Immunoglobulin G(Fc)-binding receptors on virions of herpes simplex virus type 1 and transfer of these receptors to the cell surface by infection.

Authors:  M F Para; R B Baucke; P G Spear
Journal:  J Virol       Date:  1980-05       Impact factor: 5.103

Review 5.  Monoclonal antibodies. Hybrid myelomas--a revolution in serology and immunogenetics.

Authors:  R G Kennett
Journal:  Am J Hum Genet       Date:  1979-09       Impact factor: 11.025

6.  The amino-terminal sequences of Ly-2 and Ly-3.

Authors:  I D Walker; B J Murray; L Kirszbaum; G W Chambers; N J Deacon; I F McKenzie
Journal:  Immunogenetics       Date:  1986       Impact factor: 2.846

7.  Dog homologue of human 2 -microglobulin.

Authors:  O Smithies; M D Poulik
Journal:  Proc Natl Acad Sci U S A       Date:  1972-10       Impact factor: 11.205

8.  Beta 2-microglobulin and its binding activity in serum from patients with SLE.

Authors:  P E Evrin; T Ström
Journal:  Ann Rheum Dis       Date:  1984-04       Impact factor: 19.103

9.  Polymerization of intact beta 2-microglobulin in tissue causes amyloidosis in patients on chronic hemodialysis.

Authors:  P D Gorevic; P C Munoz; T T Casey; C R DiRaimondo; W J Stone; F C Prelli; M M Rodrigues; M D Poulik; B Frangione
Journal:  Proc Natl Acad Sci U S A       Date:  1986-10       Impact factor: 11.205

10.  Rheumatoid factors from patients with rheumatoid arthritis react with Des-Lys58-beta 2m, modified beta 2-microglobulin.

Authors:  R C Williams; M H Nissen; C C Malone
Journal:  Clin Exp Immunol       Date:  1993-06       Impact factor: 4.330
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