Literature DB >> 4517941

Multiple common properties of human beta2-microglobulin and the common portion fragment derived from HL-A antigen molecules.

K Nakamuro, N Tanigaki, D Pressman.   

Abstract

11,000-Dalton common portion fragments derived from HL-A antigen molecules were isolated and found to have a significantly high homology to beta(2)-microglobulin in amino-acid composition. Common portion fragments are also very similar to beta(2)-microglobulin with respect to molecular size, charge, and distribution in tissues. Moreover, both are found in the spent culture media of human cell lines and in human plasma and urine. Thus it appears that beta(2)-microglobulin may well be the same substance as the common portion fragment of HL-A antigen molecules.

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Year:  1973        PMID： 4517941      PMCID： PMC427126          DOI： 10.1073/pnas.70.10.2863

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  13 in total

1.  Synthesis of 2 -microglobulin by stimulated lymphocytes.

Authors:  G M Bernier; M W Fanger
Journal:  J Immunol       Date:  1972-08       Impact factor: 5.422

2.  Common antigen structures of HL-A antigens. I. Antigenic determinants recognizable by rabbits on papain-solubilized HL-A molecular fragments.

Authors:  Y Miyakawa; N Tanigaki; Y Yagi; D Pressman
Journal:  Immunology       Date:  1973-01       Impact factor: 7.397

3.  Determination of HL-A zygosity by radioimmunoassay.

Authors:  Y Miyakawa; N Tanigaki; V P Kreiter; G E Moore; D Pressman
Journal:  Transplantation       Date:  1972-12       Impact factor: 4.939

4.  Assessment of compositional relatedness between proteins.

Authors:  H Metzger; M B Shapiro; J E Mosimann; J E Vinton
Journal:  Nature       Date:  1968-09-14       Impact factor: 49.962

5.  Isolation and properties of a low molecular weight beta-2-globulin occurring in human biological fluids.

Authors:  I Berggård; A G Bearn
Journal:  J Biol Chem       Date:  1968-08-10       Impact factor: 5.157

6.  Antibodies of limited heterogeneity: L chains of a single mobility.

Authors:  O A Roholt; B K Seon; D Pressman
Journal:  Immunochemistry       Date:  1970-04

7.  The destruction of serine and threonine during acid hydrolysis.

Authors:  F Downs; W Pigman
Journal:  Int J Protein Res       Date:  1969

8.  2 -Microglobulin--a free immunoglobulin domain.

Authors:  P A Peterson; B A Cunningham; I Berggård; G M Edelman
Journal:  Proc Natl Acad Sci U S A       Date:  1972-07       Impact factor: 11.205

9.  Initiation of protein synthesis at an unusual position in an immunoglobulin gene?

Authors:  O Smithies; M D Poulik
Journal:  Science       Date:  1972-01-14       Impact factor: 47.728

10.  The relationship between 2 -microglobulin and immunoglobulin in cultured human lymphoid cell lines.

Authors:  T H Hütteroth; H Cleve; S D Litwin; M D Poulik
Journal:  J Exp Med       Date:  1973-03-01       Impact factor: 14.307
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  37 in total

1.  Amino acid sequence of an immunoglobulin-like HLA antigen heavy chain domain.

Authors:  L Trägärdh; L Rask; K Wiman; J Fohlman; P A Peterson
Journal:  Proc Natl Acad Sci U S A       Date:  1979-11       Impact factor: 11.205

2.  Evolutionary relationship between immunoglobulins and transplantation antigens.

Authors:  P A Peterson; L Rask; K Sege; L Klareskog; H Anundi; L Ostberg
Journal:  Proc Natl Acad Sci U S A       Date:  1975-04       Impact factor: 11.205

3.  Soluble IL-2 receptor and beta-2 microglobulin as possible serologic markers of neurologic disease in HTLV-1 infection.

Authors:  Cristina Toledo-Cornell; Silvane Santos; Gloria Orge; Marshall J Glesby; Edgar M Carvalho
Journal:  J Med Virol       Date:  2013-09-11       Impact factor: 2.327

4.  The lymphocyte plasma membrane: locus of control in the immune response.

Authors:  L M Jerry; A K Sullivan
Journal:  In Vitro       Date:  1976-03

5.  Comparison of amino acid sequences of two human histocompatibility antigens, HLA-A2 and HLA-B7: location of putative alloantigenic sites.

Authors:  H T Orr; J A Lopez de Castro; P Parham; H L Ploegh; J L Strominger
Journal:  Proc Natl Acad Sci U S A       Date:  1979-09       Impact factor: 11.205

6.  Cell-free synthesis and segregation of beta 2-microglobulin.

Authors:  V R Lingappa; B A Cunningham; S M Jazwinski; T P Hopp; G Blobel; G M Edelman
Journal:  Proc Natl Acad Sci U S A       Date:  1979-08       Impact factor: 11.205

Review 7.  Functional sites of human class I MHC molecules: paradigms a dozen?

Authors:  P Parham
Journal:  Immunol Res       Date:  1987       Impact factor: 2.829

8.  Beta 2-microglobulin and its binding activity in serum from patients with SLE.

Authors:  P E Evrin; T Ström
Journal:  Ann Rheum Dis       Date:  1984-04       Impact factor: 19.103

9.  Complete amino acid sequence of murine beta 2-microglobulin: structural evidence for strain-related polymorphism.

Authors:  F T Gates; J E Coligan; T J Kindt
Journal:  Proc Natl Acad Sci U S A       Date:  1981-01       Impact factor: 11.205

10.  Cloning of the beta 2-microglobulin gene in the zebrafish.

Authors:  H Ono; F Figueroa; C O'hUigin; J Klein
Journal:  Immunogenetics       Date:  1993       Impact factor: 2.846
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