Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 beta-Chloro-L-alanine inhibition of the Escherichia coli alanine-valine transaminase.

Literature DB >> 3934143

beta-Chloro-L-alanine inhibition of the Escherichia coli alanine-valine transaminase.

Abstract

beta-Chloro-L-alanine, an amino acid analog which inhibits a number of enzymes, reversibly inhibited the Escherichia coli K-12 alanine-valine transaminase, transaminase C. This inhibition, along with the inhibition of transaminase B, accounted for the isoleucine-plus-valine requirement of E. coli in the presence of beta-chloro-L-alanine.

Entities: Chemical Species

Mesh：

Substances：

Year: 1985 PMID： 3934143 PMCID： PMC219336 DOI： 10.1128/jb.164.3.1350-1352.1985

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

11 in total

1. Transamination in Escherichia coli.

Authors: D RUDMAN; A MEISTER
Journal: J Biol Chem Date: 1953-02 Impact factor: 5.157

2. Regulation of transaminase C synthesis in Escherichia coli: conditional leucine auxotrophy.

Authors: D McGilvray; H E Umbarger
Journal: J Bacteriol Date: 1974-11 Impact factor: 3.490

3. Interaction of L-aspartate beta-decarboxylase with beta-chloro-L-alanine. Beta-elimination reaction and active-site labeling.

Authors: S S Tate; N M Relyea; A Meister
Journal: Biochemistry Date: 1969-12 Impact factor: 3.162

4. Inhibition studies of the enantiomers of beta chloroalanine on purified alanine racemase from B. subtilis.

Authors: L L Henderson; R B Johnston
Journal: Biochem Biophys Res Commun Date: 1976-02-09 Impact factor: 3.575

5. In vivo DNA cloning and adjacent gene fusing with a mini-Mu-lac bacteriophage containing a plasmid replicon.

Authors: E A Groisman; B A Castilho; M J Casadaban
Journal: Proc Natl Acad Sci U S A Date: 1984-03 Impact factor: 11.205

6. Role of alanine-valine transaminase in Salmonella typhimurium and analysis of an avtA::Tn5 mutant.

Authors: C M Berg; W A Whalen; L B Archambault
Journal: J Bacteriol Date: 1983-09 Impact factor: 3.490

7. Analysis of an avtA::Mu d1(Ap lac) mutant: metabolic role of transaminase C.

Authors: W A Whalen; C M Berg
Journal: J Bacteriol Date: 1982-05 Impact factor: 3.490

8. Inactivation of the dadB Salmonella typhimurium alanine racemase by D and L isomers of beta-substituted alanines: kinetics, stoichiometry, active site peptide sequencing, and reaction mechanism.

Authors: B Badet; D Roise; C T Walsh
Journal: Biochemistry Date: 1984-10-23 Impact factor: 3.162

9. Physiological characterization of polar Tn5-induced isoleucine-valine auxotrophs in Escherichia coli K.12: evidence for an internal promoter in the ilvOGEDA operon.

Authors: C M Berg; K J Shaw; J Vender; M Borucka-Mankiewicz
Journal: Genetics Date: 1979-10 Impact factor: 4.562

10. Inhibition of growth of Salmonella typhimurium and of threonine deaminase and transaminase B by beta-chloroalanine.

Authors: S M Arfin; D A Koziell
Journal: J Bacteriol Date: 1971-02 Impact factor: 3.490

8 in total

1. Genetics and regulation of the major enzymes of alanine synthesis in Escherichia coli.

Authors: Sok Ho Kim; Barbara L Schneider; Larry Reitzer
Journal: J Bacteriol Date: 2010-08-20 Impact factor: 3.490

2. Cloning and characterization of the Escherichia coli K-12 alanine-valine transaminase (avtA) gene.

Authors: M D Wang; L Liu; B M Wang; C M Berg
Journal: J Bacteriol Date: 1987-09 Impact factor: 3.490

Review 3. From microbiology to cancer biology: the Rid protein family prevents cellular damage caused by endogenously generated reactive nitrogen species.

Authors: Diana M Downs; Dustin C Ernst
Journal: Mol Microbiol Date: 2015-02-26 Impact factor: 3.501