Literature DB >> 3919751

Inhibition of food stimulated acid secretion by misoprostol, an orally active synthetic E1 analogue prostaglandin.

J K Ramage, A Denton, J G Williams.   

Abstract

The effect of 200 micrograms misoprostol (a synthetic prostaglandin E1 analogue) on food stimulated intragastric acidity has been monitored over a 9 h period in 16 normal volunteers. Misoprostol caused a significant inhibition of intragastric acidity for 2 h post-dosing, but no significant effect was seen thereafter on either basal or food stimulated acidity.

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Year:  1985        PMID： 3919751      PMCID： PMC1463799          DOI： 10.1111/j.1365-2125.1985.tb02606.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  7 in total

1.  Effect of cimetidine on 24-hour intragastric acidity in normal subjects.

Authors:  R E Pounder; J G Williams; G J Milton-Thompson; J J Misiewicz
Journal:  Gut       Date:  1976-02       Impact factor: 23.059

2.  Effects of a prostaglandin E1 derivative, SC-29333, and aspirin on gastric ionic fluxes and potential difference in dogs.

Authors:  D G Colton; D A Callison; E Z Dajani
Journal:  J Pharmacol Exp Ther       Date:  1979-08       Impact factor: 4.030

3.  Inhibition of food stimulated acid secretion by fenoctimine, a new anti-secretory agent.

Authors:  J G Williams; R J Robertson; G J Milton-Thompson
Journal:  Br J Clin Pharmacol       Date:  1983-06       Impact factor: 4.335

4.  pH or hydrogen-ion concentration in statistics?

Authors:  M Lucas
Journal:  Lancet       Date:  1977-10-15       Impact factor: 79.321

5.  24-hour control of intragastric acidity by cimetidine in duodenal-ulcer patients.

Authors:  R E Pounder; J G Williams; G J Milton-Thompson; J J Misiewicz
Journal:  Lancet       Date:  1975-11-29       Impact factor: 79.321

6.  SC-29333: a potent inhibitor of canin gastric secretion.

Authors:  E Z Dajani; D R Driskill; R G Bianchi; P W Collins; R Pappo
Journal:  Am J Dig Dis       Date:  1976-12

7.  Inhibition of nocturnal gastric secretion in normal human volunteers by misoprostol: a synthetic prostaglandin E1 methyl ester analog.

Authors:  K Akdamar; N Agrawal; A Ertan
Journal:  Am J Gastroenterol       Date:  1982-12       Impact factor: 10.864
  7 in total
  4 in total

1.  Interim results of a multicenter international comparison of misoprostol and cimetidine in the treatment of out-patients with benign gastric ulcers.

Authors:  M J Shield
Journal:  Dig Dis Sci       Date:  1985-11       Impact factor: 3.199

Review 2.  Misoprostol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the treatment of peptic ulcer disease.

Authors:  J P Monk; S P Clissold
Journal:  Drugs       Date:  1987-01       Impact factor: 9.546

3.  Helicobacter pylori infection, ABO blood group, and effect of misoprostol on gastroduodenal mucosa in NSAID-treated patients with rheumatoid arthritis.

Authors:  K Henriksson; A Uribe; B Sandstedt; C E Nord
Journal:  Dig Dis Sci       Date:  1993-09       Impact factor: 3.199

4.  Misoprostol clinical pharmacology. Establishment of activity in man.

Authors:  J A Steiner
Journal:  Dig Dis Sci       Date:  1985-11       Impact factor: 3.199
  4 in total

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