Literature DB >> 6871066

Inhibition of food stimulated acid secretion by fenoctimine, a new anti-secretory agent.

J G Williams, R J Robertson, G J Milton-Thompson.   

Abstract

The effect of fenoctimine, a new anti-secretory agent, has been studied on food stimulated acid secretion in six normal volunteers. When tested between 2 and 4 h after dosing, and compared with placebo, fenoctimine 50 mg inhibited acid secretion by a mean of 29%, 150 mg by 43% and 250 mg by 47%.

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Year:  1983        PMID： 6871066      PMCID： PMC1427921          DOI： 10.1111/j.1365-2125.1983.tb01548.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  5 in total

1.  Inhibition of food-stimulated gastric acid secretion by cimetidine.

Authors:  R E Pounder; J G Williams; R C Russell; G J Milton-Thompson; J J Misiewicz
Journal:  Gut       Date:  1976-03       Impact factor: 23.059

2.  The effect of an H2-receptor antagonist on food-stimulated acid secretion, serum gastrin, and gastric emptying in patients with duodenal ulcers. Comparison with an anticholinergic drug.

Authors:  C T Richardson; B A Bailey; J H Walsh; J S Fordtran
Journal:  J Clin Invest       Date:  1975-03       Impact factor: 14.808

3.  Inhibition of gastric acid secretion by cimetidine in patients with duodenal ulcer.

Authors:  R M Henn; J I Isenberg; V Maxwell; R A Sturdevant
Journal:  N Engl J Med       Date:  1975-08-21       Impact factor: 91.245

4.  Oxmetidine: clinical pharmacological studies with a new H2-receptor antagonist.

Authors:  J G Mills; P L Brunet; R Griffiths; R H Hunt; D Vincent; G J Milton-Thompson; W L Burland
Journal:  Gut       Date:  1982-02       Impact factor: 23.059

5.  Gastric acid secretion rate and buffer content of the stomach after eating. Results in normal subjects and in patients with duodenal ulcer.

Authors:  J S Fordtran; J H Walsh
Journal:  J Clin Invest       Date:  1973-03       Impact factor: 14.808
  5 in total
  2 in total

1.  Effect of cimetidine and pirenzepine in combination on 24 hour intragastric acidity in subjects with previous duodenal ulceration.

Authors:  J G Williams; M Deakin; J K Ramage
Journal:  Gut       Date:  1986-04       Impact factor: 23.059

2.  Inhibition of food stimulated acid secretion by misoprostol, an orally active synthetic E1 analogue prostaglandin.

Authors:  J K Ramage; A Denton; J G Williams
Journal:  Br J Clin Pharmacol       Date:  1985-01       Impact factor: 4.335
  2 in total

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