Experimental evaluation of various available contrast agents for use in the gastrointestinal tract in case of suspected leakage. Effects on peritoneum.

The effects of seven contrast agents were studied on the peritoneum of rats in order to find the most suitable and safe contrast agent in cases where leakage might be expected from the gastrointestinal tract into the peritoneal cavity. Hexabrix appeared to give the least tissue reaction, with Amipaque and Gastrografin in second place (but not significantly different statistically).