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Literature DB >> 3755525

Isolation and characterization of the human catalase gene.

F Quan, R G Korneluk, M B Tropak, R A Gravel.

Abstract

Catalase is a tetrameric hemoprotein which degrades H2O2. Recombinant phage clones containing the human catalase gene have been isolated and characterized. The gene is 34 kb long and is split into 13 exons. The precise size and location of the exons has been determined. In addition, essentially full length catalase cDNA clones have been isolated and sequenced and used to tentatively identify the 5'-end of the gene. This assignment, if correct, predicts that the region upstream of the gene does not contain a TATA box. This region is GC rich (67%) and contains several CCAAT and GGGCGG sequences which may form part of the promoter. Translation of the catalase mRNA appears to begin immediately upstream of the amino-terminal Ala residue of catalase.

Entities: Chemical Gene Species

Mesh：

Substances：
DNA
Catalase

Year: 1986 PMID： 3755525 PMCID： PMC311543 DOI： 10.1093/nar/14.13.5321

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

46 in total

1. Properties of residual catalase in the erythrocytes of Japanese-type acatalasemia.

Authors: M Ogata; J Mizugaki
Journal: Hum Genet Date: 1979-05-10 Impact factor: 4.132

Review 2. Catalase: Physical and chemical properties, mechanism of catalysis, and physiological role.

Authors: A Deisseroth; A L Dounce
Journal: Physiol Rev Date: 1970-07 Impact factor: 37.312

3. The ovalbumin gene-sequence of putative control regions.

Authors: C Benoist; K O'Hare; R Breathnach; P Chambon
Journal: Nucleic Acids Res Date: 1980-01-11 Impact factor: 16.971

4. The isolation and characterization of linked delta- and beta-globin genes from a cloned library of human DNA.

Authors: R M Lawn; E F Fritsch; R C Parker; G Blake; T Maniatis
Journal: Cell Date: 1978-12 Impact factor: 41.582

5. Regional assignment of catalase (CAT) gene to band 11p13. Association with the aniridia-Wilms' tumor-Gonadoblastoma (WAGR) complex.

Authors: C Junien; C Turleau; J de Grouchy; R Saïd; L Rethoré MO; R Tenconi; J L Dufier
Journal: Ann Genet Date: 1980

6. Assignment of the gene coding for human catalase to the short arm of chromosome 11.

Authors: P Wieacker; C R Mueller; A Mayerova; K H Grzeschik; H H Ropers
Journal: Ann Genet Date: 1980

7. Synthesis of catalase in two cell-free protein-synthesizing systems and in rat liver.

Authors: M Robbi; P B Lazarow
Journal: Proc Natl Acad Sci U S A Date: 1978-09 Impact factor: 11.205

8. DNA sequencing with chain-terminating inhibitors.

Authors: F Sanger; S Nicklen; A R Coulson
Journal: Proc Natl Acad Sci U S A Date: 1977-12 Impact factor: 11.205

9. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.

Authors: J M Chirgwin; A E Przybyla; R J MacDonald; W J Rutter
Journal: Biochemistry Date: 1979-11-27 Impact factor: 3.162

10. Acyl-Coa oxidase and hydratase-dehydrogenase, two enzymes of the peroxisomal beta-oxidation system, are synthesized on free polysomes of clofibrate-treated rat liver.

Authors: R A Rachubinski; Y Fujiki; R M Mortensen; P B Lazarow
Journal: J Cell Biol Date: 1984-12 Impact factor: 10.539

44 in total

Review 1. Import of proteins into peroxisomes and other microbodies.

Authors: M J de Hoop; G Ab
Journal: Biochem J Date: 1992-09-15 Impact factor: 3.857

2. Air pollution and homocysteine: more evidence that oxidative stress-related genes modify effects of particulate air pollution.

Authors: Cizao Ren; Sung Kyun Park; Pantel S Vokonas; David Sparrow; Elissa Wilker; Andrea Baccarelli; Helen H Suh; Katherine L Tucker; Robert O Wright; Joel Schwartz
Journal: Epidemiology Date: 2010-03 Impact factor: 4.822

10. Decreased catalase expression and increased susceptibility to oxidative stress in primary cultured corneal fibroblasts from patients with granular corneal dystrophy type II.

Authors: Seung-il Choi; Tae-im Kim; Kyu Seo Kim; Bong-Yoon Kim; So-yeon Ahn; Hyun-ju Cho; Hyung Keun Lee; Hyun-Soo Cho; Eung Kweon Kim
Journal: Am J Pathol Date: 2009-06-04 Impact factor: 4.307

Isolation and characterization of the human catalase gene.

1. Properties of residual catalase in the erythrocytes of Japanese-type acatalasemia.

Review 2. Catalase: Physical and chemical properties, mechanism of catalysis, and physiological role.

3. The ovalbumin gene-sequence of putative control regions.

4. The isolation and characterization of linked delta- and beta-globin genes from a cloned library of human DNA.

5. Regional assignment of catalase (CAT) gene to band 11p13. Association with the aniridia-Wilms' tumor-Gonadoblastoma (WAGR) complex.

6. Assignment of the gene coding for human catalase to the short arm of chromosome 11.

7. Synthesis of catalase in two cell-free protein-synthesizing systems and in rat liver.

8. DNA sequencing with chain-terminating inhibitors.

9. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.

10. Acyl-Coa oxidase and hydratase-dehydrogenase, two enzymes of the peroxisomal beta-oxidation system, are synthesized on free polysomes of clofibrate-treated rat liver.

Review 1. Import of proteins into peroxisomes and other microbodies.

2. Air pollution and homocysteine: more evidence that oxidative stress-related genes modify effects of particulate air pollution.

3. Intron loss and gain during evolution of the catalase gene family in angiosperms.

Review 4. The surprising complexity of peroxisome biogenesis.

5. Molecular evolution of maize catalases and their relationship to other eukaryotic and prokaryotic catalases.

6. Nucleotide sequence of katG, encoding catalase HPI of Escherichia coli.

7. Do exons code for structural or functional units in proteins?

8. cDNA and deduced amino acid sequence of Drosophila catalase.

9. Cloning, nucleotide sequence, and regulation of katE encoding a sigma B-dependent catalase in Bacillus subtilis.

10. Decreased catalase expression and increased susceptibility to oxidative stress in primary cultured corneal fibroblasts from patients with granular corneal dystrophy type II.