Literature DB >> 8031064

Limited effects of temafloxacin compared with ciprofloxacin on T-lymphocyte function.

K Riesbeck1, A Forsgren.   

Abstract

Temafloxacin increased interleukin-2 production and mRNA levels and enhanced thymidine incorporation in stimulated lymphocyte cultures. Gamma interferon mRNA levels were unaffected. Temafloxacin also stimulated interleukin-2 gene induction, as revealed in a chloramphenicol acetyltransferase reporter gene system. However, temafloxacin exerted significantly weaker effects in these respects than did ciprofloxacin.

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Year:  1994        PMID: 8031064      PMCID: PMC284561          DOI: 10.1128/AAC.38.4.879

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  24 in total

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Authors:  P Davey; T McDonald
Journal:  Drugs       Date:  1993       Impact factor: 9.546

2.  Mechanism of quinolone inhibition of DNA gyrase. Appearance of unique norfloxacin binding sites in enzyme-DNA complexes.

Authors:  L L Shen; W E Kohlbrenner; D Weigl; J Baranowski
Journal:  J Biol Chem       Date:  1989-02-15       Impact factor: 5.157

3.  A single point mutation in the DNA gyrase A protein greatly reduces binding of fluoroquinolones to the gyrase-DNA complex.

Authors:  C J Willmott; A Maxwell
Journal:  Antimicrob Agents Chemother       Date:  1993-01       Impact factor: 5.191

4.  Effect of 4-quinolones and novobiocin on calf thymus DNA polymerase alpha primase complex, topoisomerases I and II, and growth of mammalian lymphoblasts.

Authors:  P Hussy; G Maass; B Tümmler; F Grosse; U Schomburg
Journal:  Antimicrob Agents Chemother       Date:  1986-06       Impact factor: 5.191

5.  Regulation of interleukin 2 gene expression: discrepancy between enhancer activity and endogenous gene expression.

Authors:  I L Mårtensson; T Leanderson
Journal:  Eur J Immunol       Date:  1989-01       Impact factor: 5.532

Review 6.  Safety and tolerability of fluoroquinolones.

Authors:  S R Norrby; P S Lietman
Journal:  Drugs       Date:  1993       Impact factor: 9.546

7.  Effects of ciprofloxacin on eucaryotic pyrimidine nucleotide biosynthesis and cell growth.

Authors:  A Forsgren; A Bredberg; A B Pardee; S F Schlossman; T F Tedder
Journal:  Antimicrob Agents Chemother       Date:  1987-05       Impact factor: 5.191

8.  Antimicrobial activities of two investigational fluoroquinolones (CI-960 and E4695) against over 100 Legionella sp. isolates.

Authors:  B B Gooding; M E Erwin; M S Barrett; D M Johnson; R N Jones
Journal:  Antimicrob Agents Chemother       Date:  1992-09       Impact factor: 5.191

9.  4-Quinolone drugs affect cell cycle progression and function of human lymphocytes in vitro.

Authors:  A Forsgren; S F Schlossman; T F Tedder
Journal:  Antimicrob Agents Chemother       Date:  1987-05       Impact factor: 5.191

10.  Quinolones affect thymidine incorporation into the DNA of human lymphocytes.

Authors:  A Forsgren; A K Bergh; M Brandt; G Hansson
Journal:  Antimicrob Agents Chemother       Date:  1986-03       Impact factor: 5.191

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  5 in total

Review 1.  Interference of antibacterial agents with phagocyte functions: immunomodulation or "immuno-fairy tales"?

Authors:  M T Labro
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2.  In vitro effects of ciprofloxacin and roxithromycin on apoptosis of jurkat T lymphocytes.

Authors:  Yong-Taek Jun; Hee-Jung Kim; Min-Jin Song; Ji-Hyang Lim; Dong-Gun Lee; Kyung-Ja Han; Su-Mi Choi; Jin-Hong Yoo; Wan-Shik Shin; Jung-Hyun Choi
Journal:  Antimicrob Agents Chemother       Date:  2003-03       Impact factor: 5.191

3.  Effect of moxifloxacin on production of proinflammatory cytokines from human peripheral blood mononuclear cells.

Authors:  Jung-Hyun Choi; Min-Jin Song; Seung-Han Kim; Su-Mi Choi; Dong-Gun Lee; Jin-Hong Yoo; Wan-Shik Shin
Journal:  Antimicrob Agents Chemother       Date:  2003-12       Impact factor: 5.191

4.  Effects of fluoroquinolones on the migration of human phagocytes through Chlamydia pneumoniae-infected and tumor necrosis factor alpha-stimulated endothelial cells.

Authors:  Silvia M Uriarte; Robert E Molestina; Richard D Miller; Jorge Bernabo; Alicia Farinati; Kumiko Eiguchi; Julio A Ramirez; James T Summersgill
Journal:  Antimicrob Agents Chemother       Date:  2004-07       Impact factor: 5.191

5.  Effect of trovafloxacin on production of cytokines by human monocytes.

Authors:  A A Khan; T R Slifer; J S Remington
Journal:  Antimicrob Agents Chemother       Date:  1998-07       Impact factor: 5.191

  5 in total

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