Literature DB >> 360221

Relative sensitivities of forward and reverse mutation assays in Salmonella typhimurium.

T R Skopek, H L Liber, D A Kaden, W G Thilly.   

Abstract

Forward mutation to 8-azaguanine resistance and reverse mutation to histidine prototrophy were measured in Salmonella typhimurium after treatment with 16 mutagens of both base-substitution and frameshift classes. The two approaches were found to be equisensitive for all 16 mutagens--i.e., induction of significant mutation occurred at similar concentrations in the forward mutation assay and in the most sensitive of the five Ames tester strains.

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Year:  1978        PMID： 360221      PMCID： PMC336136          DOI： 10.1073/pnas.75.9.4465

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  8 in total

1.  Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.

Authors:  J McCann; E Choi; E Yamasaki; B N Ames
Journal:  Proc Natl Acad Sci U S A       Date:  1975-12       Impact factor: 11.205

2.  The Mutagenicity of Some Carcinogenic Compounds for Escherichia Coli.

Authors:  G H Scherr; M Fishman; R H Weaver
Journal:  Genetics       Date:  1954-03       Impact factor: 4.562

3.  Detection of carcinogens as mutagens: bacterial tester strains with R factor plasmids.

Authors:  J McCann; N E Spingarn; J Kobori; B N Ames
Journal:  Proc Natl Acad Sci U S A       Date:  1975-03       Impact factor: 11.205

4.  Quantitative forward mutation assay in Salmonella typhimurium using 8-azaguanine resistance as a genetic marker.

Authors:  T R Skopek; H L Liber; J J Krolewski; W G Thilly
Journal:  Proc Natl Acad Sci U S A       Date:  1978-01       Impact factor: 11.205

5.  An improved bacterial test system for the detection and classification of mutagens and carcinogens.

Authors:  B N Ames; F D Lee; W E Durston
Journal:  Proc Natl Acad Sci U S A       Date:  1973-03       Impact factor: 11.205

6.  Mutagenic activity of cyclophosphamide, ifosfamide, and trofosfamide in different genes of escherichia coli and salmonella typhimurium after biotransformation through extracts of rodent liver.

Authors:  J Ellenberger; G Mohn
Journal:  Arch Toxicol       Date:  1975       Impact factor: 5.153

7.  Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test.

Authors:  B N Ames; J Mccann; E Yamasaki
Journal:  Mutat Res       Date:  1975-12       Impact factor: 2.433

8.  The sporulation system of Bacillus subtilis as the basis of a multi-gene mutagen screening test.

Authors:  J T Macgregor; L E Sacks
Journal:  Mutat Res       Date:  1976-08       Impact factor: 2.433
  8 in total
  18 in total

1.  Frameshift mutagenesis of lambda prophage by 9-aminoacridine, proflavin and ICR-191.

Authors:  T R Skopek; F Hutchinson
Journal:  Mol Gen Genet       Date:  1984

2.  Aflatoxin B1 mutagenesis, DNA binding, and adduct formation in Salmonella typhimurium.

Authors:  A A Stark; J M Essigmann; A L Demain; T R Skopek; G N Wogan
Journal:  Proc Natl Acad Sci U S A       Date:  1979-03       Impact factor: 11.205

Review 3.  Sources of spontaneous mutagenesis in bacteria.

Authors:  Jeremy W Schroeder; Ponlkrit Yeesin; Lyle A Simmons; Jue D Wang
Journal:  Crit Rev Biochem Mol Biol       Date:  2017-11-06       Impact factor: 8.250

4.  Metabolically activated steviol, the aglycone of stevioside, is mutagenic.

Authors:  J M Pezzuto; C M Compadre; S M Swanson; D Nanayakkara; A D Kinghorn
Journal:  Proc Natl Acad Sci U S A       Date:  1985-04       Impact factor: 11.205

5.  There is a correlation between the DNA affinity and mutagenicity of several 3-amino-1-methyl-5H-pyrido[4,3-b]indoles.

Authors:  J M Pezzuto; P P Lau; Y Luh; P D Moore; G N Wogan; S M Hecht
Journal:  Proc Natl Acad Sci U S A       Date:  1980-03       Impact factor: 11.205

6.  Seasonal and spatial variation of the bacterial mutagenicity of fine organic aerosol in southern california.

Authors:  M P Hannigan; G R Cass; A L Lafleur; W F Busby; W G Thilly
Journal:  Environ Health Perspect       Date:  1996-04       Impact factor: 9.031

7.  Chemical and toxicological characterization of residential oil burner emissions: II. Mutagenic, tumorigenic, and potential teratogenic activity.

Authors:  A G Braun; W F Busby; H L Liber; W G Thilly
Journal:  Environ Health Perspect       Date:  1987-08       Impact factor: 9.031

8.  Generation of biologically active substances in a natural gas flame.

Authors:  A G Braun; P Pakzaban; M A Toqan; J M Beér
Journal:  Environ Health Perspect       Date:  1987-06       Impact factor: 9.031

9.  Organic emissions from coal pyrolysis: mutagenic effects.

Authors:  A G Braun; M J Wornat; A Mitra; A F Sarofim
Journal:  Environ Health Perspect       Date:  1987-08       Impact factor: 9.031

10.  Comparison of a forward and a reverse mutation assay in Salmonella typhimurium measuring L-arabinose resistance and histidine prototrophy.

Authors:  M Ruiz-Rubio; C Hera; C Pueyo
Journal:  EMBO J       Date:  1984-06       Impact factor: 11.598
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