Literature DB >> 35888197

On the Morphological Deviation in Additive Manufacturing of Porous Ti6Al4V Scaffold: A Design Consideration.

Seyed Ataollah Naghavi1, Haoyu Wang1, Swastina Nath Varma1, Maryam Tamaddon1, Arsalan Marghoub2, Rex Galbraith3, Jane Galbraith3, Mehran Moazen2, Jia Hua4, Wei Xu5, Chaozong Liu1.   

Abstract

Additively manufactured Ti scaffolds have been used for bone replacement and orthopaedic applications. In these applications, both morphological and mechanical properties are important for their in vivo performance. Additively manufactured Ti6Al4V triply periodic minimal surface (TPMS) scaffolds with diamond and gyroid structures are known to have high stiffness and high osseointegration properties, respectively. However, morphological deviations between the as-designed and as-built types of these scaffolds have not been studied before. In this study, the morphological and mechanical properties of diamond and gyroid scaffolds at macro and microscales were examined. The results demonstrated that the mean printed strut thickness was greater than the designed target value. For diamond scaffolds, the deviation increased from 7.5 μm (2.5% excess) for vertical struts to 105.4 μm (35.1% excess) for horizontal struts. For the gyroid design, the corresponding deviations were larger, ranging from 12.6 μm (4.2% excess) to 198.6 μm (66.2% excess). The mean printed pore size was less than the designed target value. For diamonds, the deviation of the mean pore size from the designed value increased from 33.1 μm (-3.0% excess) for vertical struts to 92.8 μm (-8.4% excess) for horizontal struts. The corresponding deviation for gyroids was larger, ranging from 23.8 μm (-3.0% excess) to 168.7 μm (-21.1% excess). Compressive Young's modulus of the bulk sample, gyroid and diamond scaffolds was calculated to be 35.8 GPa, 6.81 GPa and 7.59 GPa, respectively, via the global compression method. The corresponding yield strength of the samples was measured to be 1012, 108 and 134 MPa. Average microhardness and Young's modulus from α and β phases of Ti6Al4V from scaffold struts were calculated to be 4.1 GPa and 131 GPa, respectively. The extracted morphology and mechanical properties in this study could help understand the deviation between the as-design and as-built matrices, which could help develop a design compensation strategy before the fabrication of the scaffolds.

Entities:  

Keywords:  Ti6Al4V scaffolds; additive manufacturing; bone scaffolds; geometry deviation; mechanical properties; nanoindentation; surface roughness

Year:  2022        PMID: 35888197      PMCID: PMC9319900          DOI: 10.3390/ma15144729

Source DB:  PubMed          Journal:  Materials (Basel)        ISSN: 1996-1944            Impact factor:   3.748


  11 in total

1.  Characterization and biocompatibility of a titanium dental implant with a laser irradiated and dual-acid etched surface.

Authors:  Shan-Hui Hsu; Bai-Shuan Liu; Wen-Hung Lin; Heng-Chieh Chiang; Shih-Ching Huang; Shih-Shyong Cheng
Journal:  Biomed Mater Eng       Date:  2007       Impact factor: 1.300

2.  Effect of implant surface roughness and loading on peri-implant bone formation.

Authors:  Katleen Vandamme; Ignace Naert; Jozef Vander Sloten; Robert Puers; Joke Duyck
Journal:  J Periodontol       Date:  2008-01       Impact factor: 6.993

Review 3.  Effects of titanium surface topography on bone integration: a systematic review.

Authors:  Ann Wennerberg; Tomas Albrektsson
Journal:  Clin Oral Implants Res       Date:  2009-09       Impact factor: 5.977

4.  Additively manufactured metallic porous biomaterials based on minimal surfaces: A unique combination of topological, mechanical, and mass transport properties.

Authors:  F S L Bobbert; K Lietaert; A A Eftekhari; B Pouran; S M Ahmadi; H Weinans; A A Zadpoor
Journal:  Acta Biomater       Date:  2017-02-16       Impact factor: 8.947

5.  Compensation strategy to reduce geometry and mechanics mismatches in porous biomaterials built with Selective Laser Melting.

Authors:  Zahra S Bagheri; David Melancon; Lu Liu; R Burnett Johnston; Damiano Pasini
Journal:  J Mech Behav Biomed Mater       Date:  2016-05-06

6.  Mechanical and microstructural properties of polycaprolactone scaffolds with one-dimensional, two-dimensional, and three-dimensional orthogonally oriented porous architectures produced by selective laser sintering.

Authors:  Shaun Eshraghi; Suman Das
Journal:  Acta Biomater       Date:  2010-02-08       Impact factor: 8.947

7.  Histologic comparison of a thermal dual-etched implant surface to machined, TPS, and HA surfaces: bone contact in vivo in rabbits.

Authors:  Robert M London; Frank A Roberts; David A Baker; Michael D Rohrer; Robert B O'Neal
Journal:  Int J Oral Maxillofac Implants       Date:  2002 May-Jun       Impact factor: 2.804

8.  Analysing the optimal value for titanium implant roughness in bone attachment using a tensile test.

Authors:  H J Rønold; S P Lyngstadaas; J E Ellingsen
Journal:  Biomaterials       Date:  2003-11       Impact factor: 12.479

9.  High-strength porous biomaterials for bone replacement: A strategy to assess the interplay between cell morphology, mechanical properties, bone ingrowth and manufacturing constraints.

Authors:  Sajad Arabnejad; R Burnett Johnston; Jenny Ann Pura; Baljinder Singh; Michael Tanzer; Damiano Pasini
Journal:  Acta Biomater       Date:  2015-10-30       Impact factor: 8.947

10.  Surface Roughness and Morphology Customization of Additive Manufactured Open Porous Ti6Al4V Structures.

Authors:  Grzegorz Pyka; Greet Kerckhofs; Ioannis Papantoniou; Mathew Speirs; Jan Schrooten; Martine Wevers
Journal:  Materials (Basel)       Date:  2013-10-22       Impact factor: 3.623

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