Fen Yang1,2, Ying Chang2, Lu Yang3, Zhijie Jia2, Jiewei Liu2, Yan Wang4,5. 1. Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, 300020, China. 2. Shanxi Eye Hospital, TaiYuan, 030001, China. 3. Shanxi Aier eye Hospital, Taiyuan, 030012, China. 4. Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, 300020, China. wangyan7143@vip.sina.com. 5. Tianjin Eye Institute, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin Eye Hospital, No 4. Gansu Road, He-ping District, Tianjin, 300020, China. wangyan7143@vip.sina.com.
Abstract
AIM: To assess the repeatability of a new optical biometer (OA-2000, Tomey, Japan) based on swept-source optical coherence tomography (SS-OCT) and Placido-disk topography in dry eyes with cataracts. METHOD: A cross-sectional study was performed. Two hundred sixteen eyes of 216 cataract patients were enrolled in our hospital from March 2020 to December 2020. According to the subjective symptoms and objective examination of dry eye, the patients were assigned to dry eye group and non-dry eye group. Axial length (AL), keratometry readings (K), lens thickness (LT), anterior chamber depth (ACD), central corneal thickness (CCT) and white-to-white (WTW) distance were measured by one skilled operator. The repeatability of each parameter based on within-subject standard deviation (Sw), repeatability limit of standard deviation (2.77Sw), coefficient of variation (CoV) and intra-class correlation coefficient (ICC) was evaluated. RESULT: There was no significant difference in age and gender between the two groups. NiaBUT and NifBUT in the dry eye group were significantly lower than those in the non-dry eye group (p < 0.05). The ICC mean values of AL, K1, K2, Km, ACD, LT and CCT were all greater than 0.960, except WTW. In the dry eye group, except CCT and WTW, the Sw scores for other biometric parameters were lower than 0.201, 2.77Sw scores were lower than 0.557, CoV(%) was less than 1%, and ICC mean values were greater than 0.964. Among them, the Sw scores for AL, LT and ACD were lower than 0.035, the 2.77Sw scores were lower than 0.097, and the ICC mean values are greater than 0.990. CONCLUSION: The ocular biological parameters measured by SS-OCT have good repeatability for age-related cataract patients with dry eyes, in which the AL, LT and ACD are the highest repeatable. However, more attention should be paid for WTW in clinical application since repeatability influence.
AIM: To assess the repeatability of a new optical biometer (OA-2000, Tomey, Japan) based on swept-source optical coherence tomography (SS-OCT) and Placido-disk topography in dry eyes with cataracts. METHOD: A cross-sectional study was performed. Two hundred sixteen eyes of 216 cataract patients were enrolled in our hospital from March 2020 to December 2020. According to the subjective symptoms and objective examination of dry eye, the patients were assigned to dry eye group and non-dry eye group. Axial length (AL), keratometry readings (K), lens thickness (LT), anterior chamber depth (ACD), central corneal thickness (CCT) and white-to-white (WTW) distance were measured by one skilled operator. The repeatability of each parameter based on within-subject standard deviation (Sw), repeatability limit of standard deviation (2.77Sw), coefficient of variation (CoV) and intra-class correlation coefficient (ICC) was evaluated. RESULT: There was no significant difference in age and gender between the two groups. NiaBUT and NifBUT in the dry eye group were significantly lower than those in the non-dry eye group (p < 0.05). The ICC mean values of AL, K1, K2, Km, ACD, LT and CCT were all greater than 0.960, except WTW. In the dry eye group, except CCT and WTW, the Sw scores for other biometric parameters were lower than 0.201, 2.77Sw scores were lower than 0.557, CoV(%) was less than 1%, and ICC mean values were greater than 0.964. Among them, the Sw scores for AL, LT and ACD were lower than 0.035, the 2.77Sw scores were lower than 0.097, and the ICC mean values are greater than 0.990. CONCLUSION: The ocular biological parameters measured by SS-OCT have good repeatability for age-related cataract patients with dry eyes, in which the AL, LT and ACD are the highest repeatable. However, more attention should be paid for WTW in clinical application since repeatability influence.
Authors: Jennifer P Craig; Kelly K Nichols; Esen K Akpek; Barbara Caffery; Harminder S Dua; Choun-Ki Joo; Zuguo Liu; J Daniel Nelson; Jason J Nichols; Kazuo Tsubota; Fiona Stapleton Journal: Ocul Surf Date: 2017-07-20 Impact factor: 5.033
Authors: Preeya K Gupta; Owen J Drinkwater; Keith W VanDusen; Ashley R Brissette; Christopher E Starr Journal: J Cataract Refract Surg Date: 2018-08-02 Impact factor: 3.351