| Literature DB >> 35635745 |
Antoinette Poulton1, Li Peng Evelyn Chen1, Gezelle Dali1, Michael Fox1, Robert Hester1.
Abstract
BACKGROUND: Considered a facet of behavioral impulsivity, response inhibition facilitates adaptive and goal-directed behavior. It is often assessed using the Stop-Signal Task (SST), which is presented on stand-alone computers under controlled laboratory conditions. Sample size may consequently be a function of cost or time and sample diversity constrained to those willing or able to attend the laboratory. Statistical power and generalizability of results might, in turn, be impacted. Such limitations may potentially be overcome via the implementation of web-based testing.Entities:
Keywords: Stop-Signal Task; cognition; inhibitory control; online assessment; response inhibition; web-based assessment
Mesh:
Year: 2022 PMID: 35635745 PMCID: PMC9153905 DOI: 10.2196/32922
Source DB: PubMed Journal: J Med Internet Res ISSN: 1438-8871 Impact factor: 7.076
Figure 1Initial instructions (provided across 2 screens) for the web-based Stop-Signal Task.
Figure 2Schematic representation of Go and Stop trials in the practice and experimental blocks of the web-based Stop-Signal Task. Practice trials have an inter-trial interval (ITI) of 4250 milliseconds and comprise a blank screen (1000 milliseconds), fixation cross (250 milliseconds), stimulus presentation (1000 milliseconds), and feedback screen (2000 milliseconds). Experimental trials have an ITI of 2250 milliseconds and comprise a blank screen (1000 milliseconds), fixation cross (250 milliseconds), and stimulus presentation (1000 milliseconds).
Figure 3Study Participation Flowchart.
Demographic statistics and Pearson correlation coefficients with laboratory-based and independent stop-signal reaction times (n=123).
| Characteristics | Value, mean (SD) | Correlation with SSRTa | |||
| Laboratory-based stop-signal task, | Independent stop-signal task, | ||||
| Age (years) | 19.73 (1.97) | 0.09 | .34 | 0.07 | .45 |
| Education (years) | 13.50 (1.07) | 0.01 | .94 | 0.06 | .54 |
| Alcohol Use Disorders Identification Test score | 4.60 (4.50) | 0.15 | .10 | 0.17 | .07 |
| Alcohol, Smoking and Substance Involvement Screen Test score | 4.07 (8.68) | 0.17 | .05 | 0.16 | .08 |
aSSRT: stop-signal reaction time (Go reaction time – meta–stop signal delay).
Laboratory-based and independent Stop-Signal Task (SST) variables plus differences between variables.
| Variables | SST, mean (SD) | 95% CI | Cohen | Bayes factor | |||
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| Laboratory-based | Independent |
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| Go accuracy | 97.96 (1.90) | 97.12 (2.33) | 4.12 (122) | <.001 | 0.43 to 1.24 | 0.37 | 242.35a |
| Go reaction time (milliseconds) | 490.75 (62.71) | 485.56 (60.88) | 1.00 (122) | .32 | –5.13 to 15.52 | 0.09 | 0.16 |
| Go omissions | 0.61 (0.99) | 0.67 (1.35) | –0.44 (120) | .66 | –0.29 to 0.18 | 0.04 | 0.11 |
| Go errors | 1.43 (1.59) | 2.22 (1.97) | –4.24 (120) | <.001 | –1.13 to –0.41 | 0.39 | 362.27a |
| Go errors reaction time (milliseconds) | 431.43 (87.46) | 413.44 (82.88) | 2.48 (69) | .02 | 6.64 to 61.05 | 0.30 | 2.26a |
| Intraindividual SD | 83.03 (26.09) | 86.20 (22.60) | –1.27 (122) | .21 | –8.10 to 1.76 | 0.12 | 0.22 |
| Stop accuracy | 50.10 (2.32) | 49.61 (2.12) | 2.23 (122) | .03 | 0.05 to 0.93 | 0.20 | 1.08 |
| Failed (correct key) stop reaction time (milliseconds) | 452.04 (53.27) | 446.04 (51.81) | 1.26 (120) | .21 | –3.22 to 14.56 | 0.12 | 0.22 |
| Failed (incorrect key) stop reaction time (milliseconds) | 379.58 (58.23) | 339.29 (80.89) | 2.01 (24) | .06 | –1.24 to 99.94 | 0.40 | 1.18 |
| Meta stop-signal delay (as timed by each participant’s computer; milliseconds) | 250.23 (72.64) | 223.11 (62.86) | 4.42 (122) | <.001 | 14.98 to 39.26 | 0.40 | 718.50a |
| Stop-signal reaction timeb (milliseconds) | 240.53 (35.64) | 262.45 (36.43) | –6.61 (122) | <.001 | –28.48 to –15.36 | 0.60 | 9050000a |
aEvidence for the alternative hypothesis.
bStop-signal reaction time = Go reaction time – meta–stop-signal delay.