Literature DB >> 3562246

Oligodeoxyribonucleotides containing 1,3-propanediol as nucleoside substitute.

F Seela, K Kaiser.   

Abstract

1,3-Propanediol was protected with one dimethoxytrityl residue and converted into the methoxy- and cyanoethoxyphosphoramidites 2a and 2b, respectively. Solid-phase oligonucleotide synthesis, employing the phosphoramidite 2a resulted in the dodecamers d(CGCGAATTCGCG) (6-9), in which dA or dT residues were replaced by 1,3-propanediol. These oligomers showed a high tendency to form hairpins. Their phosphodiester bonds between the 3'-position of a nucleoside and the propanediol moiety was not cleaved by snake venom phosphodiesterase.

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Year:  1987        PMID： 3562246      PMCID： PMC340719          DOI： 10.1093/nar/15.7.3113

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  12 in total

1.  The dispersion of the hyperchromic effect in thermally induced transitions of nucleic acids.

Authors:  G FELSENFELD; G SANDEEN
Journal:  J Mol Biol       Date:  1962-12       Impact factor: 5.469

2.  Thermodynamic behaviour of the heptadecadeoxynucleotide d(CGCGCGTTTTTCGCGCG) forming B and Z hairpins in aqueous solution.

Authors:  L E Xodo; G Manzini; F Quadrifoglio; G A van der Marel; J H van Boom
Journal:  Nucleic Acids Res       Date:  1986-07-11       Impact factor: 16.971

3.  Spectral analysis of high resolution direct-derivative melting curves of DNA for instantaneous and total base composition.

Authors:  R D Blake; S G Lefoley
Journal:  Biochim Biophys Acta       Date:  1978-04-27

4.  Salt-dependent conformational transitions in the self-complementary deoxydodecanucleotide d(CGCAATTCGCG): evidence for hairpin formation.

Authors:  L A Marky; K S Blumenfeld; S Kozlowski; K J Breslauer
Journal:  Biopolymers       Date:  1983-04       Impact factor: 2.505

5.  Purification and properties of venom phosphodiesterase.

Authors:  M Laskowski
Journal:  Methods Enzymol       Date:  1980       Impact factor: 1.600

6.  Purification and properties of 3-methyladenine-DNA glycosylase from Escherichia coli.

Authors:  S Riazuddin
Journal:  Methods Enzymol       Date:  1980       Impact factor: 1.600

7.  Uracil-DNA glycosylase from Escherichia coli.

Authors:  T Lindahl
Journal:  Methods Enzymol       Date:  1980       Impact factor: 1.600

8.  Crystal structure analysis of a complete turn of B-DNA.

Authors:  R Wing; H Drew; T Takano; C Broka; S Tanaka; K Itakura; R E Dickerson
Journal:  Nature       Date:  1980-10-23       Impact factor: 49.962

9.  NMR, CD and IR spectroscopies of a tridecanucleotide containing a no-base residue: coexistence of B and Z conformations.

Authors:  S Pochet; T Huynh-Dinh; J M Neumann; S Tran-Dinh; S Adam; J Taboury; E Taillandier; J Igolen
Journal:  Nucleic Acids Res       Date:  1986-01-24       Impact factor: 16.971

10.  Polymer support oligonucleotide synthesis XVIII: use of beta-cyanoethyl-N,N-dialkylamino-/N-morpholino phosphoramidite of deoxynucleosides for the synthesis of DNA fragments simplifying deprotection and isolation of the final product.

Authors:  N D Sinha; J Biernat; J McManus; H Köster
Journal:  Nucleic Acids Res       Date:  1984-06-11       Impact factor: 16.971
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  15 in total

1.  Intercalating nucleic acids containing insertions of 1-O-(1-pyrenylmethyl)glycerol: stabilisation of dsDNA and discrimination of DNA over RNA.

Authors:  Ulf B Christensen; Erik B Pedersen
Journal:  Nucleic Acids Res       Date:  2002-11-15       Impact factor: 16.971

2.  Cleavage of DNA without loss of genetic information by incorporation of a disaccharide nucleoside.

Authors:  Koen Nauwelaerts; Karen Vastmans; Matheus Froeyen; Veerle Kempeneers; Jef Rozenski; Helmut Rosemeyer; Arthur Van Aerschot; Roger Busson; Jeffrey C Lacey; Ekaterina Efimtseva; Sergey Mikhailov; Eveline Lescrinier; Piet Herdewijn
Journal:  Nucleic Acids Res       Date:  2003-12-01       Impact factor: 16.971

3.  A novel strategy for site-directed chemical reactions in single stranded DNA--absorption and NMR spectroscopic studies of model compounds.

Authors:  U Asseline; T Rozelle; G Lancelot; N T Thuong
Journal:  Nucleic Acids Res       Date:  1992-09-25       Impact factor: 16.971

4.  Extension product capture improves genomic sequencing and DNase I footprinting by ligation-mediated PCR.

Authors:  V T Törmänen; P M Swiderski; B E Kaplan; G P Pfeifer; A D Riggs
Journal:  Nucleic Acids Res       Date:  1992-10-25       Impact factor: 16.971

5.  Circular dichroism studies of an oligodeoxyribonucleotide containing a hairpin loop made of a hexaethylene glycol chain: conformation and stability.

Authors:  M Durand; K Chevrie; M Chassignol; N T Thuong; J C Maurizot
Journal:  Nucleic Acids Res       Date:  1990-11-11       Impact factor: 16.971

6.  Selection of hammerhead ribozymes for optimum cleavage of interleukin 6 mRNA.

Authors:  C Hendrix; J Anné; B Joris; A Van Aerschot; P Herdewijn
Journal:  Biochem J       Date:  1996-03-01       Impact factor: 3.857

7.  Antigen structural requirements for recognition by a cyclobutane thymine dimer-specific monoclonal antibody.

Authors:  Y Komatsu; T Tsujino; T Suzuki; O Nikaido; E Ohtsuka
Journal:  Nucleic Acids Res       Date:  1997-10-01       Impact factor: 16.971

8.  Steric factors influencing hybridisation of nucleic acids to oligonucleotide arrays.

Authors:  M S Shchepinov; S C Case-Green; E M Southern
Journal:  Nucleic Acids Res       Date:  1997-03-15       Impact factor: 16.971

9.  Synthesis, thermal stability and reactivity towards 9-aminoellipticine of double-stranded oligonucleotides containing a true abasic site.

Authors:  J R Bertrand; J J Vasseur; B Rayner; J L Imbach; J Paoletti; C Paoletti; C Malvy
Journal:  Nucleic Acids Res       Date:  1989-12-25       Impact factor: 16.971

10.  3'-modified antisense oligodeoxyribonucleotides complementary to calmodulin mRNA alter behavioral responses in Paramecium.

Authors:  R D Hinrichsen; D Fraga; M W Reed
Journal:  Proc Natl Acad Sci U S A       Date:  1992-09-15       Impact factor: 11.205
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