| Literature DB >> 35409775 |
Anum Nisar1, Juan Yin2, Yiping Nan1, Huanyuan Luo3, Dongfang Han1, Lei Yang1, Jiaying Li1, Duolao Wang3, Atif Rahman4, Xiaomei Li1.
Abstract
BACKGROUND: Rates of perinatal depression in China are high. The Thinking Healthy Programme is a WHO-endorsed, evidence-based psychosocial intervention for perinatal depression, requiring five days of face-to-face training by a specialist trainer. Given the paucity of specialist trainers and logistical challenges, standardized training of large numbers of nurses is a major challenge for scaling up. We developed an electronic training programme (e-training) which eliminates the need for specialist-led, face-to-face training. The aim of this study was to evaluate the effectiveness of the e-training compared to conventional face-to-face training in nursing students.Entities:
Keywords: Thinking Healthy Programme; perinatal depression; psychosocial intervention; technology; training
Mesh:
Year: 2022 PMID: 35409775 PMCID: PMC8998312 DOI: 10.3390/ijerph19074094
Source DB: PubMed Journal: Int J Environ Res Public Health ISSN: 1660-4601 Impact factor: 3.390
Figure 1(CONSORT flow diagram).
Socio demographic characteristics of intervention and control arms.
| Characteristic | E-Training ( | Specialist Led Training ( | |
|---|---|---|---|
| Mean age (SD), Median (IQR) | 20 (1.94); 20 (18–22) | 19.45 (1.57); 19 (18–21) | 0.13 |
| Gender | 0.08 | ||
| Male | 7 (14.9%) | 14 (29.8%) | |
| Female | 40 (85.1%) | 33 (70.2%) | |
| Grade | 0.09 | ||
| Year 1 | 23 (48.9%) | 31 (66.0%) | |
| Year 4 | 24 (51.1%) | 16 (34.0%) | |
| Work experience ( | 1.00 | ||
| Yes | 10 (21.3%) | 10 (21.3%) | |
| No | 37 (78.7%) | 37 (78.7%) | |
| Prior mental health training ( | 10.12 | 11.02 | 0.61 |
| Yes | 3 (6.4%) | 1 (2.1%) | |
| No | 44 (93.6%) | 46 (97.9%) | |
| Knowledge of perinatal depression ** | 17.04 (1.40) | 17.23 (1.13) | 0.43 |
* Compared using chi-square test. ** Compared using Fisher exact test. IQR, interquartile range.
Mean differences in primary and secondary outcome scores (competence) at post-training and three months post-training.
| Generalized Linear Mixed Model Analysis * | ||||||
|---|---|---|---|---|---|---|
| Primary Analysis | Covariate Analysis | Imputation Analysis | ||||
| Mean Difference (95% CI) | Mean Difference (95% CI) | Mean Difference (95% CI) | ||||
| ENACT Scores | ||||||
| Post-training | −1.35 (−3.17, 0.46) | 0.14 | −1.20 (−3.05, 0.65) | 0.20 | −1.18 (−3.04, 0.66) | 0.20 |
| Post 3 months | −0.48 (−2.35, 1.39) | 0.61 | −0.32 (−2.23, 1.59) | 0.73 | 0.16 (−1.69, 2.01) | 0.86 |
| Attitude and beliefs scores | ||||||
| Post-training | 2.149 (−1.338, 5.636) | 0.22 | 0.49 (0.01, 0.98) | 0.16 | 0.48 (0.05, 0.92) | 0.28 |
| Post 3 months | −1.686 (−5.358, 1.986) | 0.36 | −1.544 (−5.275, 2.188) | 0.41 | −1.532 (−5.080, 2.015) | 0.39 |
| Self-Efficacy scores | ||||||
| Post-training | −19.13 (39.54, 1.27) | 0.06 | −16.44 (−37.23, 4.34) | 0.11 | −15.93 (−35.71, 3.84) | 0.11 |
| Post 3 months | −9.17 (−30.44, 12.08) | 0.39 | −6.52 (−28.22, 15.16) | 0.55 | −7.24 (−27.02, 12.53) | 0.46 |
* GLMM: Generalised linear mixed models (GLMM). GLMM has study arm (intervention or control), follow-up visit (Post training or 3-months follow up), interaction of study arm and follow-up visit as fixed effects, and subject as random effect * p value for non-inferiority test.
Summary statistics of primary and secondary outcomes by treatment and time.
| Category | Outcome | Month | Statistics | E-Training | Specialist Led | All |
|---|---|---|---|---|---|---|
| Primary outcome | ENACT | Post training | 49, 45.73 (4.03) | 47, 47.08 (4.53) | 96, 46.39 (4.31) | |
| Post 3 months | 44, 42.16 (4.85) | 47, 42.65 (4.56) | 91, 42.41 (4.68) | |||
| Secondary outcome | Attitude and Beliefs | Post training | 47, 32.81 (8.60) | 47, 30.66 (7.38) | 94, 31.73 (8.04) | |
| Post 3 months | 40, 31.78 (7.72) | 45, 33.47 (10.01) | 85, 32.67 (9.00) | |||
| Self-efficacy | Post training | 47, 159.11 (53.88) | 45, 178.24 (40.78) | 92, 168.47 (48.62) | ||
| Post 3 months | 40, 178.20 (54.19) | 45, 187.38 (47.05) | 85, 183.06 (50.44) |
SD, standard deviation.
Estimates of treatment differences in means of primary outcome: Subgroup analysis *.
| Variable | Subgroup | Mean Difference |
| Estimate (95% CI) | |
|---|---|---|---|---|---|
| Age | <19 | A vs. B at month 0 | 52 | −1.19 (−3.83, 1.44) | 0.36 |
| A vs. B at month 3 | 52 | −0.86 (−3.63, 1.89) | 0.53 | ||
| ≥19 | A vs. B at month 0 | 44 | −1.51 (−4.13, 1.09) | 0.24 | |
| A vs. B at month 3 | 44 | −0.28 (−2.92, 2.39) | 0.82 | ||
| Gender | Male | A vs. B at month 0 | 21 | −1.26 (−5.47, 2.95) | 0.53 |
| A vs. B at month 3 | 21 | −0.51 (−4.72, 3.69) | 0.80 | ||
| Female | A vs. B at month 0 | 75 | −1.18 (−3.31, 0.94) | 0.26 | |
| A vs. B at month 3 | 75 | −0.41 (−2.60, 1.77) | 0.70 | ||
| Grade | 1st year | A vs. B at month 0 | 56 | −1.04 (−3.52, 1.43) | 0.40 |
| A vs. B at month 3 | 56 | −0.35 (−3.00, 2.28) | 0.78 | ||
| 4th year | A vs. B at month 0 | 40 | −1.66 (−4.58, 1.25) | 0.25 | |
| A vs. B at month 3 | 40 | −0.76 (−3.67, 2.15) | 0.59 | ||
| Work experience | Yes | A vs. B at month 0 | 20 | −1.34 (−4.53, 1.85) | 0.38 |
| A vs. B at month 3 | 20 | −1.08 (−4.36, 2.18) | 0.49 | ||
| No | A vs. B at month 0 | 76 | −1.34 (−3.51, 0.82) | 0.22 | |
| A vs. B at month 3 | 76 | −0.30 (−2.53, 1.92) | 0.78 |
* Not adjusted for covariates. A = e-training, B = specialist led training.
Estimates of odds ratio of primary outcomes from generalized linear mixed models.
| Primary Analysis * | Covariate Analysis ** | Imputation Analysis **† | |||||
|---|---|---|---|---|---|---|---|
| Outcome | Odds Ratio | Estimate (95% CI) | Estimate (95% CI) | Estimate (95% CI) | |||
| ENACT (≥43) | A vs. B at month 0 | 0.61 (0.17, 2.10) | 0.42 | 0.59 (0.16, 2.10) | 0.41 | 0.59 (0.16, 2.12) | 0.42 |
| A vs. B at month 3 | 1.36 (0.57, 3.26) | 0.47 | 1.33 (0.53, 3.37) | 0.53 | 1.67 (0.67, 4.15) | 0.26 | |
* Not adjusted for covariates. ** Adjusted for age, gender, grade, work experience and prior mental health training where missing data were imputed with medians. † Missing outcome data were imputed using the last observation carried forward method. A = e-training, B = specialist led training.
Figure 2Scatter plot of ENACT scores of the intervention and control groups from post-training to post three months.