Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Phorbol ester induces c-sis gene transcription in stem cell line K-562.

Literature DB >> 3466024

Phorbol ester induces c-sis gene transcription in stem cell line K-562.

O R Colamonici, J B Trepel, C A Vidal, L M Neckers.

Abstract

The phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA) induced megakaryoblastic differentiation and c-sis expression in the human hematopoietic stem cell line K-562. This induction occurred at the transcriptional level, as determined by a nuclear runoff transcriptional assay, and was not a generalized effect of TPA, since the treatment of other hematopoietic cell lines and normal peripheral blood lymphocytes with TPA did not result in the appearance of c-sis mRNA.

Entities: Chemical Gene Species

Mesh：

Substances：

Year: 1986 PMID： 3466024 PMCID： PMC367717 DOI： 10.1128/mcb.6.5.1847-1850.1986

Source DB: PubMed Journal: Mol Cell Biol ISSN： 0270-7306 Impact factor: 4.272

29 in total

1. Platelet alpha granules contain a growth factor for fibroblasts.

Authors: D R Kaplan; F C Chao; C D Stiles; H N Antoniades; C D Scher
Journal: Blood Date: 1979-06 Impact factor: 22.113

2. Activated human monocytes express the c-sis proto-oncogene and release a mediator showing PDGF-like activity.

Authors: Y Martinet; P B Bitterman; J F Mornex; G R Grotendorst; G R Martin; R G Crystal
Journal: Nature Date: 1986 Jan 9-15 Impact factor: 49.962

3. Cellular genes analogous to retroviral onc genes are transcribed in human tumour cells.

Authors: A Eva; K C Robbins; P R Andersen; A Srinivasan; S R Tronick; E P Reddy; N W Ellmore; A T Galen; J A Lautenberger; T S Papas; E H Westin; F Wong-Staal; R C Gallo; S A Aaronson
Journal: Nature Date: 1982-01-14 Impact factor: 49.962

4. A human onc gene homologous to the transforming gene (v-sis) of simian sarcoma virus.

Authors: R Dalla-Favera; E P Gelmann; R C Gallo; F Wong-Staal
Journal: Nature Date: 1981-07-02 Impact factor: 49.962

5. Early effects of the tumor-promoting phorbol ester 12-O-tetradecanoylphorbol-13-acetate on the cell cycle traverse of asynchronous HeLa cells.

Authors: V Kinzel; J Richards; M Stöhr
Journal: Cancer Res Date: 1981-01 Impact factor: 12.701

6. Expression of cellular homologues of retroviral onc genes in human hematopoietic cells.

Authors: E H Westin; F Wong-Staal; E P Gelmann; R Dalla-Favera; T S Papas; J A Lautenberger; A Eva; E P Reddy; S R Tronick; S A Aaronson; R C Gallo
Journal: Proc Natl Acad Sci U S A Date: 1982-04 Impact factor: 11.205

7. Heterogeneity in the cellular commitment of a human leukemic cell line: K 562.

Authors: W Vainchenker; U Testa; J Guichard; M Titeux; J Breton-Gorius
Journal: Blood Cells Date: 1981

8. Simian sarcoma virus onc gene, v-sis, is derived from the gene (or genes) encoding a platelet-derived growth factor.

Authors: R F Doolittle; M W Hunkapiller; L E Hood; S G Devare; K C Robbins; S A Aaronson; H N Antoniades
Journal: Science Date: 1983-07-15 Impact factor: 47.728

9. Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus.

Authors: M D Waterfield; G T Scrace; N Whittle; P Stroobant; A Johnsson; A Wasteson; B Westermark; C H Heldin; J S Huang; T F Deuel
Journal: Nature Date: 1983 Jul 7-13 Impact factor: 49.962

10. Constitutive expression of platelet glycoproteins by the human leukemia cell line K562.

Authors: A M Gewirtz; D Burger; T A Rado; E J Benz; R Hoffman
Journal: Blood Date: 1982-09 Impact factor: 22.113

29 in total

1. Transcription induction of c-Ki-ras with the tumour promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) in normal and transformed liver cells.

Authors: S O Chan; S S Wong; D C Yeung
Journal: Mol Cell Biochem Date: 1992-11-04 Impact factor: 3.396

2. Dominant mutations in a gene encoding a putative protein kinase (BCK1) bypass the requirement for a Saccharomyces cerevisiae protein kinase C homolog.

Authors: K S Lee; D E Levin
Journal: Mol Cell Biol Date: 1992-01 Impact factor: 4.272

Review 3. A model to account for the effects of oncogenes, TPA, and retinoic acid on the regulation of genes involved in metastasis.

Authors: J Pohl; A Radler-Pohl; V Schirrmacher
Journal: Cancer Metastasis Rev Date: 1988-12 Impact factor: 9.264

4. Regulation of expression of the c-sis proto-oncogene.

Authors: L Ratner
Journal: Nucleic Acids Res Date: 1989-06-12 Impact factor: 16.971

5. Triplex targeting of human PDGF-B (c-sis, proto-oncogene) promoter specifically inhibits factors binding and PDGF-B transcription.

Authors: J Liu; R Xu; Y Jin; D Wang
Journal: Nucleic Acids Res Date: 2001-02-01 Impact factor: 16.971

6. Differential expression of jun and fos genes during differentiation of mouse P19 embryonal carcinoma cells.

Authors: R P de Groot; J Schoorlemmer; S T van Genesen; W Kruijer
Journal: Nucleic Acids Res Date: 1990-06-11 Impact factor: 16.971

7. Isolation of a mammalian homologue of a fission yeast differentiation regulator.

Authors: H Yamamoto; K Tsukahara; Y Kanaoka; S Jinno; H Okayama
Journal: Mol Cell Biol Date: 1999-05 Impact factor: 4.272

8. Platelet-derived growth factor B-chain gene expression in mesangial cells: effect of phorbol ester on gene transcription and mRNA stability.

Authors: B Bhandari; K Woodruff; H E Abboud
Journal: Mol Cell Biochem Date: 1994-11-09 Impact factor: 3.396

9. Regulation of platelet-derived growth factor gene expression by transforming growth factor beta and phorbol ester in human leukemia cell lines.

Authors: T P Mäkelä; R Alitalo; Y Paulsson; B Westermark; C H Heldin; K Alitalo
Journal: Mol Cell Biol Date: 1987-10 Impact factor: 4.272

10. Identification and characterization of an essential, activating regulatory element of the human SIS/PDGFB promoter in human megakaryocytes.

Authors: H M Jin; M L Brady; W E Fahl
Journal: Proc Natl Acad Sci U S A Date: 1993-08-15 Impact factor: 11.205