Literature DB >> 34619743

Pregnant Individuals' Views on Fetal Tissue Research in the United States.

Natalie C Spach1, Elana F Jaffe, Kristen A Sullivan, Ilona T Goldfarb, Jean R Anderson, Jenell Coleman, Sappho Z Gilbert, Marielle S Gross, Lisa Rahangdale, Ruth R Faden, Anne D Lyerly.   

Abstract

OBJECTIVE: Fetal tissue research has driven significant medical advances but remains publicly contentious in the United States. The views of pregnant individuals in the United States regarding the donation of fetal tissue offer an important and previously unexplored perspective on this issue.
METHODS: We conducted a secondary analysis of data from two separate, broader qualitative studies. Pregnant and recently pregnant individuals (N=79) from clinical sites at the University of North Carolina at Chapel Hill, Johns Hopkins University, and Massachusetts General Hospital were interviewed individually using a semi-structured guide addressing a range of issues related to infectious disease research and pregnancy, including the acceptability of fetal tissue research. Interviews were transcribed, coded, and analyzed for emergent themes.
RESULTS: Among this sample of predominantly Black (61%), reproductive-aged pregnant and recently pregnant participants, the majority (72%) generally supported fetal tissue research. The following three themes were identified: choice, respect, and meaning. Respondents discussed the deeply personal nature of decisions surrounding fetal tissue research, emphasizing the importance of informed consent and respect for the person's emotional state when approaching for consent. The ways in which participants regarded how to respectfully handle fetal tissue also shaped views about the acceptability of donation, both for and against. For many participants, fetal tissue donation to research represented one way of ascribing meaning to pregnancy termination or loss.
CONCLUSION: Among this diverse sample of pregnant and recently pregnant individuals, most were supportive of fetal tissue donation for research. A better understanding of pregnant individuals' views on this topic may lead to policies and practices that are congruent with the needs and values of people facing decisions regarding the disposition of fetal remains.
Copyright © 2021 by the American College of Obstetricians and Gynecologists. Published by Wolters Kluwer Health, Inc. All rights reserved.

Entities:  

Mesh:

Year:  2021        PMID: 34619743      PMCID: PMC8542627          DOI: 10.1097/AOG.0000000000004576

Source DB:  PubMed          Journal:  Obstet Gynecol        ISSN: 0029-7844            Impact factor:   7.661


  19 in total

Review 1.  Fetal tissue research.

Authors:  M C Coutts
Journal:  Kennedy Inst Ethics J       Date:  1993-03

2.  The truth about fetal tissue research.

Authors:  Meredith Wadman
Journal:  Nature       Date:  2015-12-10       Impact factor: 49.962

3.  Applications for Research Concerning Fetal or Placental Tissue and Expected Institutional Review Board Responses.

Authors:  Lynn Borgatta; David Kaufman; Judith Parsells Kelly; David Babaian; Mary Banks
Journal:  J Empir Res Hum Res Ethics       Date:  2017-05-23       Impact factor: 1.742

Review 4.  Ethics of fetal tissue transplantation.

Authors:  L M Sanders; L Giudice; T A Raffin
Journal:  West J Med       Date:  1993-09

5.  Posttraumatic growth following pregnancy termination for fetal abnormality: the predictive role of coping strategies and perinatal grief.

Authors:  Caroline Lafarge; Kathryn Mitchell; Pauline Fox
Journal:  Anxiety Stress Coping       Date:  2017-01-12

Review 6.  Humanized mice: A brief overview on their diverse applications in biomedical research.

Authors:  Shigeyoshi Fujiwara
Journal:  J Cell Physiol       Date:  2017-06-15       Impact factor: 6.384

7.  Factors that affect infertility patients' decisions about disposition of frozen embryos.

Authors:  Anne Drapkin Lyerly; Karen Steinhauser; Emily Namey; James A Tulsky; Robert Cook-Deegan; Jeremy Sugarman; David Walmer; Ruth Faden; Edward Wallach
Journal:  Fertil Steril       Date:  2006-05-04       Impact factor: 7.329

8.  Attitudes of women to fetal tissue research.

Authors:  F Anderson; A Glasier; J Ross; D T Baird
Journal:  J Med Ethics       Date:  1994-03       Impact factor: 2.903

Review 9.  Abortion Stigma: A Systematic Review.

Authors:  Franz Hanschmidt; Katja Linde; Anja Hilbert; Steffi G Riedel-Heller; Anette Kersting
Journal:  Perspect Sex Reprod Health       Date:  2016-03-31

10.  Women's Views About a Paternal Consent Requirement for Biomedical Research in Pregnancy.

Authors:  Kristen A Sullivan; Maggie Little; Nora E Rosenberg; Tiwonge Mtande; Chifundo Zimba; Elana Jaffe; Jean Anderson; Jenell S Coleman; Sappho Gilbert; Marielle S Gross Wolf; Irving Hoffman; Lisa Rahangdale; Ruth Faden; Anne Drapkin Lyerly
Journal:  J Empir Res Hum Res Ethics       Date:  2018-07-12       Impact factor: 1.742

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