Literature DB >> 8236984

Ethics of fetal tissue transplantation.

L M Sanders1, L Giudice, T A Raffin.   

Abstract

Now that the Clinton Administration has overturned the ban on federal funding for fetal tissue transplantation, old ethical issues renew their relevance and new ethical issues arise. Is fetal tissue transplantation necessary and beneficial? Are fetal rights violated by the use of fetal tissue in research? Is there a moral danger that the potential of fetal tissue donation will encourage elective abortions? Should pregnant women be allowed to designate specific fetal transplant recipients? What criteria should be used to select fetal tissue transplants? Whose consent should be required for the use of fetal tissue for transplantation? We review the current state of clinical research with fetal tissue transplantation, the legal history of fetal tissue research, the major arguments against the use of fetal tissue for transplantation, and the new postmoratorium ethical dilemmas. We include recommendations for guidelines to govern the medical treatment of fetal tissue in transplantation.

Entities:  

Keywords:  Analytical Approach; Genetics and Reproduction; Health Care and Public Health; Uniform Anatomical Gift Act

Mesh:

Year:  1993        PMID: 8236984      PMCID: PMC1011357     

Source DB:  PubMed          Journal:  West J Med        ISSN: 0093-0415


  26 in total

Review 1.  Pancreas transplantation--1991.

Authors:  J S Najarian; D E Sutherland
Journal:  Transplant Proc       Date:  1992-08       Impact factor: 1.066

2.  The ethical use of human fetal tissue in medicine. Stanford University Medical Center Committee on Ethics.

Authors:  H T Greely; T Hamm; R Johnson; C R Price; R Weingarten; T Raffin
Journal:  N Engl J Med       Date:  1989-04-20       Impact factor: 91.245

3.  In-utero transplantation of stem cells in bare lymphocyte syndrome.

Authors:  J L Touraine; D Raudrant; C Royo; A Rebaud; M G Roncarolo; G Souillet; N Philippe; F Touraine; H Bétuel
Journal:  Lancet       Date:  1989-06-17       Impact factor: 79.321

4.  In-utero transplantation of fetal liver haemopoietic stem cells in monkeys.

Authors:  M R Harrison; R N Slotnick; T M Crombleholme; M S Golbus; A F Tarantal; E D Zanjani
Journal:  Lancet       Date:  1989-12-16       Impact factor: 79.321

5.  The use of adrenal medullary and fetal grafts as a treatment for Parkinson disease.

Authors:  A N Lieberman
Journal:  N Y State J Med       Date:  1988-06

6.  Implantation of a foetal thymus, restoring immunological competence in a patient with thymic aplasia (Digeorge's syndrome).

Authors:  C S August; F S Rosen; R M Filler; C A Janeway; B Markowski; H E Kay
Journal:  Lancet       Date:  1968-12-07       Impact factor: 79.321

7.  Genug ist genug: a fetus is not a kidney.

Authors:  K Nolan
Journal:  Hastings Cent Rep       Date:  1988-12       Impact factor: 2.683

8.  Transplantation of human fetal dopamine cells for Parkinson's disease. Results at 1 year.

Authors:  C R Freed; R E Breeze; N L Rosenberg; S A Schneck; T H Wells; J N Barrett; S T Grafton; S C Huang; D Eidelberg; D A Rottenberg
Journal:  Arch Neurol       Date:  1990-05

9.  Multicenter study of autologous adrenal medullary transplantation to the corpus striatum in patients with advanced Parkinson's disease.

Authors:  C G Goetz; C W Olanow; W C Koller; R D Penn; D Cahill; R Morantz; G Stebbins; C M Tanner; H L Klawans; K M Shannon
Journal:  N Engl J Med       Date:  1989-02-09       Impact factor: 91.245

10.  The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function.

Authors:  J M McCune; R Namikawa; H Kaneshima; L D Shultz; M Lieberman; I L Weissman
Journal:  Science       Date:  1988-09-23       Impact factor: 47.728

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  3 in total

1.  Pregnant Individuals' Views on Fetal Tissue Research in the United States.

Authors:  Natalie C Spach; Elana F Jaffe; Kristen A Sullivan; Ilona T Goldfarb; Jean R Anderson; Jenell Coleman; Sappho Z Gilbert; Marielle S Gross; Lisa Rahangdale; Ruth R Faden; Anne D Lyerly
Journal:  Obstet Gynecol       Date:  2021-11-01       Impact factor: 7.661

2.  Long-Term Evaluation of Intranigral Transplantation of Human iPSC-Derived Dopamine Neurons in a Parkinson's Disease Mouse Model.

Authors:  Sébastien Brot; Nabila Pyrenina Thamrin; Marie-Laure Bonnet; Maureen Francheteau; Maëlig Patrigeon; Laure Belnoue; Afsaneh Gaillard
Journal:  Cells       Date:  2022-05-10       Impact factor: 7.666

3.  Holistic Approach of Swiss Fetal Progenitor Cell Banking: Optimizing Safe and Sustainable Substrates for Regenerative Medicine and Biotechnology.

Authors:  Alexis Laurent; Nathalie Hirt-Burri; Corinne Scaletta; Murielle Michetti; Anthony S de Buys Roessingh; Wassim Raffoul; Lee Ann Applegate
Journal:  Front Bioeng Biotechnol       Date:  2020-10-23
  3 in total

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