| Literature DB >> 34556627 |
Qiuping Huang1,2, Xinxin Chen1,2, Shucai Huang3, Tianli Shao4, Zhenjiang Liao1,2, Shuhong Lin1,2, Yifan Li1,2, Jing Qi5, Yi Cai4, Hongxian Shen6,7.
Abstract
The coronavirus disease 2019 (COVID-19) has adversely influenced human physical and mental health, including emotional disorders and addictions. This study examined substance and Internet use behavior and their associations with anxiety and depression during the COVID-19 pandemic. An online self-report questionnaire was administered to 2196 Chinese adults between February 17 and 29, 2020. The questionnaire contained the seven-item Generalized Anxiety Disorder Scale (GAD-7) and Patient Health Questionnaire (PHQ-9), questions on demographic information, and items about substance and Internet use characteristics. Our results revealed that males consumed less alcohol (p < 0.001) and areca-nut (p = 0.012) during the pandemic than before the pandemic. Age, gender, education status, and occupation significantly differed among increased substance users, regular substance users, and nonsubstance users. Time spent on the Internet was significantly longer during the pandemic (p < 0.001) and 72% of participants reported increased dependence on the Internet. Compared to regular Internet users, increased users were more likely to be younger and female. Multiple logistic regression analysis revealed that age <33 years (OR = 2.034, p < 0.001), increased substance use (OR = 3.439, p < 0.001), and increased Internet use (OR = 1.914, p < 0.001) were significantly associated with depression. Moreover, anxiety was significantly related to female gender (OR = 2.065, p < 0.001), "unmarried" status (OR = 1.480, p = 0.017), nonstudents (OR = 1.946-3.030, p = 0.001), and increased substance use (OR = 4.291, p < 0.001). Although there was a significant decrease in social substance use during the pandemic, more attention should be paid to increased Internet use. Increased Internet use was significantly associated with both anxiety and depression, and increased substance use was related to depression. Professional support should be provided to vulnerable individuals to prevent addiction.Entities:
Mesh:
Year: 2021 PMID: 34556627 PMCID: PMC8459580 DOI: 10.1038/s41398-021-01614-1
Source DB: PubMed Journal: Transl Psychiatry ISSN: 2158-3188 Impact factor: 7.989
Substance use and comparison between pre-pandemic and during the pandemic by each substance.
| Male (751, 34.2%) | Female (1445, 65.8%) | Total (2196, 100%) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Before | During | Before | During | Before | During | ||||
| Tobacco | 246 (32.8) | 238 (31.7) | 0.229 | 27 (1.9) | 23 (1.6) | 0.424 | 273 (12.4) | 261 (11.9) | 0.111 |
| Alcohol | 262 (34.9) | 229 (30.5) | <0.001 | 92 (6.4) | 80 (5.5) | 0.162 | 354 (16.1) | 309 (14.1) | <0.001 |
| Sedative hypnotic | 18 (2.4) | 13 (1.7) | 0.227 | 32 (2.2) | 28 (1.9) | 0.424 | 50 (2.3) | 41 (1.9) | 0.108 |
| Areca-nut | 71 (9.5) | 59 (7.9) | 0.012 | 14 (1.0) | 11 (0.8) | 0.375 | 85 (3.9) | 70 (3.2) | 0.004 |
| Illicit drugsa | 4 (0.5) | 4 (0.5) | 1.000 | 4 (0.3) | 1 (0.1) | 0.250 | 8 (0.4) | 5 (0.2) | 0.453 |
| Othersb | 9 (1.2) | 12 (1.6) | 0.453 | 23 (1.6) | 21 (1.5) | 0.804 | 32 (1.5) | 33 (1.5) | 1.000 |
| None | 385 (51.3) | 400 (53.3) | 0.105 | 1304 (90.2) | 1317 (91.1) | 0.154 | 1689 (76.9) | 1717 (78.2) | 0.025 |
aIllicit drugs include heroin, methamphetamine, ketamine, cocaine, and cannabis.
bOthers include café, oryzanol, and any other substances participants did not disclose.
Comparison among different types of substance use by socio-demographic variables.
| Characteristics | Increased substance users ( | Regular substance users ( | Non-substance users ( | Paired comparisons | ||
|---|---|---|---|---|---|---|
| Age | ||||||
| <33 | 54 (43.2) | 208 (42.0) | 834 (52.9) | 20.283 | <0.001 | 3* |
| ≥33 | 71 (56.8) | 287 (58.0) | 742 (47.1) | |||
| Gender | ||||||
| Male | 86 (68.8) | 260 (52.5) | 405 (25.7) | 190.993 | <0.001 | 1*;2*;3* |
| Female | 39 (31.2) | 235 (47.5) | 1171 (74.3) | |||
| Education | ||||||
| High school and below | 26 (20.8) | 128 (25.9) | 304 (19.3) | 9.849 | 0.007 | 3* |
| College and above | 99 (79.2) | 367 (74.1) | 1272 (80.7) | |||
| Occupation | ||||||
| Physical labor | 43 (34.4) | 112 (22.6) | 392 (24.9) | 28.958 | <0.001 | 2*;3* |
| Mental labor | 41 (32.8) | 145 (29.3) | 377 (23.9) | |||
| Students | 33 (26.4) | 183 (37.0) | 685 (53.5) | |||
| Unemployed | 8 (6.4) | 55 (11.1) | 122 (7.7) | |||
| Marital status | ||||||
| Married | 53 (42.4) | 193 (39.0) | 639 (40.5) | 0.622 | 0.733 | |
| Unmarried | 72 (57.6) | 302 (61.0) | 937 (59.5) | |||
| Place of residence | ||||||
| Hubei | 10 (8.0) | 19 (3.8) | 60 (3.8) | 5.312 | 0.070 | |
| Other places | 115 (92.0) | 476 (96.2) | 1516 (96.2) | |||
1: Increased Substance Users vs. Regular Substance Users.
2: Increased Substance Users vs. Nonsubstance Users.
3: Regular Substance Users vs. Nonsubstance Users.
*p < 0.01.
Distribution of the main Internet behaviors before and during the pandemic.
| Internet behaviors | Main use | |
|---|---|---|
| Before | During | |
| Internet gaming | 270 (12.3) | 282 (12.8) |
| Short videos | 341 (15.5) | 322 (14.7) |
| Films and television | 469 (21.4) | 453 (20.6) |
| Network novels | 185 (8.4) | 154 (7.0) |
| Shopping online | 284 (12.9) | 66 (3.0) |
| Browsing health information | 249 (11.3) | 666 (30.3) |
| Othersa | 398 (18.1) | 253 (11.5) |
aOthers include Weibo, Zhihu, working online, and any other Internet behaviors participants did not disclose.
Comparison between increased and regular Internet users by socio-demographic variables.
| Characteristics | Increased Internet users ( | Regular Internet users ( | ||
|---|---|---|---|---|
| Age | ||||
| <33 | 813 (51.4) | 283 (46.0) | 5.178 | 0.023 |
| ≥33 | 768 (48.6) | 332 (54.0) | ||
| Gender | ||||
| Male | 517 (32.7) | 234 (38.0) | 5.627 | 0.018 |
| Female | 1064 (67.3) | 381 (62.0) | ||
| Education | ||||
| High school and below | 317 (20.1) | 141 (22.9) | 2.219 | 0.136 |
| College and above | 1264 (79.9) | 474 (77.1) | ||
| Occupation | ||||
| Physical labor | 396 (25.0) | 151 (24.6) | 1.987 | 0.575 |
| Metal labor | 396 (25.0) | 167 (27.2) | ||
| Students | 660 (41.7) | 241 (39.2) | ||
| Unemployed | 129 (8.2) | 56 (9.1) | ||
| Marital status | ||||
| Married | 691 (42.4) | 249 (39.5) | 1.567 | 0.213 |
| Unmarried | 938 (57.6) | 381 (60.5) | ||
| Place of residence | ||||
| Hubei | 63 (4.0) | 26 (4.2) | 0.067 | 0.796 |
| Other places | 1518 (96.0) | 589 (95.8) | ||
Socio-demographic, substance, and Internet use characteristics and comparison between positive and negative depression by variables.
| Characteristics | Depression positive ( | Depression negative ( | ||
|---|---|---|---|---|
| Age | ||||
| <33 | 179 (64.4) | 917 (47.8) | 26.693 | <0.001 |
| ≥33 | 99 (35.6) | 1001 (52.2) | ||
| Gender | ||||
| Male | 83 (29.9) | 668 (34.8) | 2.667 | 0.102 |
| Female | 195 (70.1) | 1250 (65.2) | ||
| Education | ||||
| High school and below | 68 (24.5) | 390 (20.3) | 2.505 | 0.113 |
| College and above | 210 (75.5) | 1528 (79.7) | ||
| Occupation | ||||
| Physical labor | 80 (28.8) | 467 (24,3) | 4.948 | 0.176 |
| Mental labor | 70 (25.2) | 493 (25.7) | ||
| Students | 100 (36.0) | 801 (41.8) | ||
| Unemployed | 28 (10.1) | 157 (8.2) | ||
| Marital status | ||||
| Married | 123 (44.2) | 762 (39.7) | 2.058 | 0.151 |
| Unmarried | 155 (55.8) | 1156 (60.3) | ||
| Place of residence | ||||
| Hubei | 17 (6.1) | 72 (3.8) | 3.481 | 0.062 |
| Other places | 261 (93.9) | 1846 (96.2) | ||
| Substance use | ||||
| Increased users | 38 (13.7) | 87 (4.5) | 37.732 | <0.001 |
| Regular users | 57 (20.5) | 438 (22.8) | ||
| Non-users | 183 (65.8) | 1393 (72.6) | ||
| Internet use | ||||
| Increased users | 231 (83.1) | 1350 (70.4) | 19.447 | <0.001 |
| Regular users | 47 (16.9) | 568 (29.6) | ||
Sociodemographic, substance and Internet use characteristics and comparison between positive and negative anxiety by variables.
| Characteristics | Anxiety positive ( | Anxiety negative ( | ||
|---|---|---|---|---|
| Age | ||||
| <33 | 85 (44.7) | 1011 (50.4) | 2.226 | 0.136 |
| ≥33 | 105 (55.3) | 995 (49.6) | ||
| Gender | ||||
| Male | 52 (27.4) | 699 (34.8) | 4.312 | 0.038 |
| Female | 138 (72.6) | 1307 (65.2) | ||
| Education | ||||
| High school and below | 42 (22.1) | 416 (20.7) | 0.197 | 0.657 |
| College and above | 148 (77.9) | 1590 (79.3) | ||
| Occupation | ||||
| Physical labor | 61 (32.1) | 486 (24.2) | 24.645 | <0.001 |
| Mental labor | 55 (28.9) | 508 (25.3) | ||
| Students | 48 (25.3) | 853 (42.5) | ||
| Unemployed | 26 (13.7) | 159 (7.9) | ||
| Marital status | ||||
| Married | 62 (32.6) | 823 (41.0) | 5.084 | 0.024 |
| Unmarried | 128 (67.4) | 1183 (59.0) | ||
| Place of residence | ||||
| Hubei | 12 (6.3) | 77 (3.8) | 2.739 | 0.098 |
| Other places | 178 (93.7) | 1929 (96.2) | ||
| Substance use | ||||
| Increased users | 27 (14.2) | 98(4.9) | 28.969 | <0.001 |
| Regular users | 44 (23.2) | 451 (22.5) | ||
| Non-users | 119 (62.6) | 1457 (72.6) | ||
| Internet use | ||||
| Increased users | 147 (77.4) | 1434 (71.5) | 2.979 | 0.084 |
| Regular users | 43 (22.6) | 572 (28.5) | ||
Results of multiple logistic regression analysis on factors significantly associated with depression and anxiety.
| Variables | OR (95%CI) | |
|---|---|---|
| Age(<33 vs. ≥33) | <0.001 | 2.034 (1.558, 2.656) |
| Substance use (regular users vs. nonusers) | 0.493 | 1.119 (0.811, 1.543) |
| Substance use (increased users vs. nonusers) | <0.001 | 3.439 (2.257, 5.238) |
| Internet use (increased users vs. regular users) | <0.001 | 1.914 (1.371, 2.670) |
| Gender (female vs. male) | <0.001 | 2.065 (1.433, 2.977) |
| Material status (unmarried vs. married) | 0.017 | 1.480 (1.072, 2.043) |
| Occupation (physical labor with students) | <0.001 | 2.334 (1.560, 3.494) |
| Occupation (mental labor with students) | 0.001 | 1.946 (1.293, 2.930) |
| Occupation (unemployed with students) | <0.001 | 3.030 (1.815, 5.059) |
| Substance use (regular users vs. nonusers) | 0.095 | 1.379 (0.946, 2.012) |
| Substance use (increased users vs. nonusers) | <0.001 | 4.291 (2.595, 7.097) |