Literature DB >> 34302665

Transplantation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in a Mouse Myocardial Infarction Model.

Takeshi Hatani1, Yoshinori Yoshida2.   

Abstract

Myocardial infarction is caused by a lack of oxygen due to blockage of a coronary artery and is a common cause of heart failure. Despite therapeutic advances, the prognosis of patients with heart failure is poor. One of the reasons is that present therapeutic approaches do not restore the loss of cardiac tissue. Stem cell-based therapies have the potential to regenerate the myocardium, and numerous studies using stem cells have shown improved cardiac function and reduced infarct size. In this chapter, we describe our methodology for transplanting human induced pluripotent stem cell-derived cardiomyocytes into immunodeficient mouse hearts with myocardial infarction.
© 2021. Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Cardiomyocyte transplantation; Human induced pluripotent stem cell-derived cardiomyocytes; Myocardial infarction; Regeneration therapy

Year:  2021        PMID： 34302665     DOI： 10.1007/978-1-0716-1484-6_24

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  11 in total

1.  Injury models to study cardiac remodeling in the mouse: myocardial infarction and ischemia-reperfusion.

Authors:  Daniel J Luther; Charles K Thodeti; J Gary Meszaros
Journal:  Methods Mol Biol       Date:  2013

Review 2.  Cell therapy for heart failure: a comprehensive overview of experimental and clinical studies, current challenges, and future directions.

Authors:  Santosh K Sanganalmath; Roberto Bolli
Journal:  Circ Res       Date:  2013-08-30       Impact factor: 17.367

3.  A Murine Model of Myocardial Ischemia-Reperfusion Injury.

Authors:  Zhaobin Xu; Kevin E McElhanon; Eric X Beck; Noah Weisleder
Journal:  Methods Mol Biol       Date:  2018

4.  More 'malignant' than cancer? Five-year survival following a first admission for heart failure.

Authors:  S Stewart; K MacIntyre; D J Hole; S Capewell; J J McMurray
Journal:  Eur J Heart Fail       Date:  2001-06       Impact factor: 15.534

5.  Induction of Human Induced Pluripotent Stem Cells to Cardiomyocytes Using Embryoid Bodies.

Authors:  Takeshi Hatani; Kenji Miki; Yoshinori Yoshida
Journal:  Methods Mol Biol       Date:  2018

6.  SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells.

Authors:  Nicole C Dubois; April M Craft; Parveen Sharma; David A Elliott; Edouard G Stanley; Andrew G Elefanty; Anthony Gramolini; Gordon Keller
Journal:  Nat Biotechnol       Date:  2011-10-23       Impact factor: 54.908

7.  Trends in the incidence of myocardial infarction and in mortality due to coronary heart disease, 1987 to 1994.

Authors:  W D Rosamond; L E Chambless; A R Folsom; L S Cooper; D E Conwill; L Clegg; C H Wang; G Heiss
Journal:  N Engl J Med       Date:  1998-09-24       Impact factor: 91.245

8.  Nano-structural analysis of engrafted human induced pluripotent stem cell-derived cardiomyocytes in mouse hearts using a genetic-probe APEX2.

Authors:  Takeshi Hatani; Shunsuke Funakoshi; Thomas J Deerinck; Eric A Bushong; Takeshi Kimura; Hiroshi Takeshima; Mark H Ellisman; Masahiko Hoshijima; Yoshinori Yoshida
Journal:  Biochem Biophys Res Commun       Date:  2018-10-15       Impact factor: 3.575

9.  Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts.

Authors:  James J H Chong; Xiulan Yang; Creighton W Don; Elina Minami; Yen-Wen Liu; Jill J Weyers; William M Mahoney; Benjamin Van Biber; Savannah M Cook; Nathan J Palpant; Jay A Gantz; James A Fugate; Veronica Muskheli; G Michael Gough; Keith W Vogel; Cliff A Astley; Charlotte E Hotchkiss; Audrey Baldessari; Lil Pabon; Hans Reinecke; Edward A Gill; Veronica Nelson; Hans-Peter Kiem; Michael A Laflamme; Charles E Murry
Journal:  Nature       Date:  2014-04-30       Impact factor: 49.962

10.  Enhanced engraftment, proliferation, and therapeutic potential in heart using optimized human iPSC-derived cardiomyocytes.

Authors:  Shunsuke Funakoshi; Kenji Miki; Tadashi Takaki; Chikako Okubo; Takeshi Hatani; Kazuhisa Chonabayashi; Misato Nishikawa; Ikue Takei; Akiko Oishi; Megumi Narita; Masahiko Hoshijima; Takeshi Kimura; Shinya Yamanaka; Yoshinori Yoshida
Journal:  Sci Rep       Date:  2016-01-08       Impact factor: 4.379
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