Literature DB >> 341887

The first step in the activation of chicken pepsinogen is similar to that of prochymosin.

H Keilova, V Kostka, J Kay.   

Abstract

Chicken pepsinogen was incubated at pH2.5 with pepstatin. The zymogen activated itself by a sequential mechanism and an intact peptide derived from residues 1-26 in the protein was released in the first step. This peptide was found to inhibit the milk-clotting activities of pig and chicken pepsins and calf chymosin but to different extents.

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Year:  1977        PMID： 341887      PMCID： PMC1183738          DOI： 10.1042/bj1670855

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  11 in total

1.  Identification of an enzymatically active intermediate in the activation of porcine pepsinogen.

Authors:  K A Christensen; V B Pedersen; B Foltmann
Journal:  FEBS Lett       Date:  1977-04-15       Impact factor: 4.124

Review 2.  The mechanism of the catalytic action of pepsin and related acid proteinases.

Authors:  J S Fruton
Journal:  Adv Enzymol Relat Areas Mol Biol       Date:  1976

3.  Penicillopepsin from Penicillium janthinellum crystal structure at 2.8 A and sequence homology with porcine pepsin.

Authors:  I N Hsu; L T Delbaere; M N James; T Hofmann
Journal:  Nature       Date:  1977-03-10       Impact factor: 49.962

4.  Homology among acid proteases: comparison of crystal structures at 3A resolution of acid proteases from Rhizopus chinensis and Endothia parasitica.

Authors:  E Subramanian; I D Swan; M Liu; D R Davies; J A Jenkins; I J Tickle; T L Blundell
Journal:  Proc Natl Acad Sci U S A       Date:  1977-02       Impact factor: 11.205

5.  The activation of bovine pepsinogen. Sequence of the peptides released, identification of a pepsin inhibitor.

Authors:  M Harboe; P M Andersen; B Foltmann; J Kay; B Kassell
Journal:  J Biol Chem       Date:  1974-07-25       Impact factor: 5.157

6.  The kinetics of the conversion of chicken pepsinogen to chicken pepsin.

Authors:  Z Bohak
Journal:  Eur J Biochem       Date:  1973-02-01

7.  Pepsin inhibitory activity amongst activation peptides of pepsinogen.

Authors:  W Anderson; J E Harthill
Journal:  Nature       Date:  1973-06-15       Impact factor: 49.962

8.  Conversion of pepsinogen into pepsin is not a one-step process.

Authors:  C W Dykes; J Kay
Journal:  Biochem J       Date:  1976-01-01       Impact factor: 3.857

9.  A turbidimetric milk-clotting assay for pepsin.

Authors:  P McPhie
Journal:  Anal Biochem       Date:  1976-05-21       Impact factor: 3.365

10.  Interaction of pepstatin with pig pepsinogen.

Authors:  J Kay; C W Dykes
Journal:  Biochem J       Date:  1976-08-01       Impact factor: 3.857
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  2 in total

1.  Comparison between the monomeric and binary-complex forms of procarboxypeptidase A from whole pig pancreas.

Authors:  M C Martínez; F X Avilés; B Sansegundo; C M Cuchillo
Journal:  Biochem J       Date:  1981-07-01       Impact factor: 3.857

2.  The effects of lactoyl-pepstatin and the pepsin inhibitor peptide on pig cathepsin D.

Authors:  J Kay; E G Afting; T Aoyagi; B M Dunn
Journal:  Biochem J       Date:  1982-06-01       Impact factor: 3.857
  2 in total

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