Does Fish Oil Reduce the Risk of Cardiovascular Events and Death? Recent Level 1 Evidence Says Yes: PRO: Fish Oil is Useful to Prevent or Treat Cardiovascular Disease.

Over the past decade there has been a considerable debate whether fish oil supplementation works to prevent and/or treat cardiovascular disease. This is due to the fact that previous studies testing fish oil in Italy and Japan found significant reductions in all-cause mortality, sudden cardiac death, and cardiovascular events, whereas more recent studies have in general been considered negative. We will discuss the reasons for these discrepancies and pave a better path forward when it comes to interpreting studies testing fish oil for the prevention or treatment of cardiovascular disease. Copyright 2021 by the Missouri State Medical Association.