| Literature DB >> 34139876 |
Deborah J MacDonald1,2, Nick D Clement1, Colin R Howie1,2, Chloe E H Scott1,2.
Abstract
AIMS: The primary aim was to assess the patient-perceived effect of restrictions imposed due to COVID-19 on rehabilitation following total hip arthroplasty (THA) and total knee arthroplasty (TKA). Secondary aims were to assess perceived restrictions, influence on mental health, and functional outcome compared to patients undergoing surgery without restriction.Entities:
Keywords: Anxiety; COVID-19; Depression; Mental health; Physical health; Rehabilitation; Total joint replacement
Year: 2021 PMID: 34139876 PMCID: PMC8244798 DOI: 10.1302/2633-1462.26.BJO-2021-0004.R1
Source DB: PubMed Journal: Bone Jt Open ISSN: 2633-1462
Responses to the effect COVID-19 had on postoperative recovery for the study cohort.
| Question | Response | Total, n % | Joint, n (%) | OR (95% CI) | p-value | |
|---|---|---|---|---|---|---|
| THA (n = 48) | TKA (n = 57) | |||||
| Limited recovery due to COVID-19? | Yes | 50 (47.6) | 22 (45.8) | 28 (49.1) | 0.95 (0.43 to 2.07) | 0.896 |
| No | 53 (50.5) | 24 (50.0) | 29 (50.9) | |||
| Missing | 2 (1.9) | 2 (4.2) | 0 | |||
| Did you receive physiotherapy after surgery? | Yes | 28 (26.7) | 12 (25.0) | 16 (28.1) | 0.90 (0.38 to 2.17) | 0.822 |
| No | 75 (71.4) | 34 (70.8) | 41 (71.9) | |||
| Missing | 2 (1.9) | 2 (4.2) | 0 | |||
| Concerns about joint but not able to contact anyone? | Yes | 23 (22.3) | 7 (14.6) | 16 (28.1) | 0.45 (0.17 to 1.21) | 0.107 |
| No | 81 (77.1) | 40 (83.3) | 41 (71.9) | |||
| Missing | 1 (1.0) | 1 (2.1) | 0 | |||
| Were you diagnosed with COVID-19 post-surgery? | Yes | 2 (1.9) | 2 (4.2) | 0 (0) | N/A | 0.116 |
| No | 102 (97.1) | 45 (93.8) | 57 (100) | |||
| Missing | 1 (1.0) | 1 (2.1) | 0 | |||
| In light of COVID-19 restrictions would you have had your surgery? | Yes | 93 (88.6) | 43 (89.6) | 50 (87.7) | 1.08 (0.27 to 4.26) | 0.918 |
| No | 9 (8.6) | 4 (8.3) | 5 (8.8) | |||
| Missing | 3 (2.9) | 1 (2.1) | 2 (3.5) | |||
| Do you feel your mental health has deteriorated? | Yes | 26 (24.8) | 13 (27.1) | 13 (22.8) | 1.24 (0.51 to 3.01) | 0.642 |
| No | 76 (72.4) | 34 (70.8) | 42 (73.7) | |||
| Missing | 3 (2.9) | 1 (2.1) | 2 (3.5) | |||
| Do you feel depressed? | Yes | 18 (17.1) | 9 (18.8) | 9 (15.8) | 0.81 (0.29 to 2.24) | 0.688 |
| No | 87 (82.9) | 39 (81.3) | 48 (84.2) | |||
| Missing | 0 | 0 | 0 | |||
| Do you feel anxious? | Yes | 28 (26.7) | 14 (29.2) | 14 (24.6) | 0.79 (0.33 to 1.88) | 0.595 |
| No | 77 (73.3) | 34 (70.8) | 43 (75.4) | |||
| Missing | 0 | 0 | 0 | |||
Chi-squared test unless otherwise stated.
Fisher's exact test.
N/A, not applicable; OR, odds ratio; THA, total hip arthroplasty; TKA, total knee arthroplasty.
Patient demographic data and preoperative functional scores for patients undergoing total hip arthroplasty according to group. Two patients from the total hip arthroplasty group did not complete the question as to whether their recovery was limited and thus were excluded from analysis.
| Demographic | Limited by COVID-19 | OR/difference (95% CI) | p-value | |
|---|---|---|---|---|
| Yes (n = 50) | No (n = 53) | |||
|
| OR 1.32 (0.29 to 1.39) | 0.251 | ||
| Male | 18 | 25 | ||
| Female | 32 | 28 | ||
| Mean age, yrs (SD) | 68.3 (9.5) | 70.1 (10.8) | Diff 1.8 (-2.2 to 5.8) | 0.373 |
| Mean BMI, kg/m2 (SD) | 30.6 (5.2) | 29.7 (6.7) | Diff 0.9 (-1.5 to 3.3) | 0.451 |
|
| ||||
| No disease | Reference | |||
| Connect tissue | 7 | 8 | OR 1.09 (0.37 to 3.27) | 0.875 |
| Diabetes | 9 | 6 | OR 0.58 (0.19 to 1.77) | 0.337 |
| Back pain | 23 | 16 | OR 0.51 (0.23 to 1.14) | 0.098 |
| Hypertension | 13 | 14 | OR 1.02 (0.42 to 2.46) | 0.962 |
|
| OR 0.95 (0.44 to 2.07) | 0.896 | ||
| THA | 22 | 24 | ||
| TKA | 28 | 29 | ||
|
| ||||
|
| ||||
| Preoperative | 18.6 (8.4) | 20.0 (7.7) | Diff 1.3 (-3.4 to 6.1) | 0.568 |
| Postoperative | 33.8 (9.2) | 39.3 (10.1) | Diff 5.4 (-0.3 to 11.2) | 0.064 |
|
| ||||
| Preoperative | 18.8 (7.9) | 21.2 (7.2) | Diff 2.4 (-1.7 to 6.3) | 0.244 |
| Postoperative | 30.8 (7.8) | 40.3 (6.2) | Diff 9.5 (5.8 to 13.3) | < 0.001 |
|
| ||||
| Preoperative | 0.315 (0.316) | 0.392 (0.315) | Diff 0.077 (-0.046 to 0.201) | 0.216 |
| Postoperative | 0.635 (0.226) | 0.833 (0.214) | Diff 0.198 (0.112 to 0.283) | < 0.001 |
|
| OR 5.63 (1.15 to 27.52) | 0.019 | ||
| Yes | 40 | 50 | ||
| No | 9 | 2 | ||
| Not answered | 1 | 1 | ||
Chi-squared test.
Independent-samples t-test.
Fisher's exact test
CI, confidence interval; EQ-5D, EuroQol five-dimension; N/A, not applicable; OHS, Oxford Hip Score; OKS, Oxford Knee Score; OR, odds ratio; SD, standard deviation; THA, total hip arthroplasty; TKA, total knee arthroplasty.
Reasons for patients stating their recovery after surgery was limited due to COVID-19.
| Question | Response | Cohort, n (%) | Joint, n (%) | Odds ratio (95% CI) | p-value | |
|---|---|---|---|---|---|---|
| THA | TKA | |||||
| Limited access to physiotherapy | Yes | 30 (60) | 12 (54.5) | 18 (64.3) | 1.50 (0.48 to 4.70) | 0.485 |
| No | 20 (40) | 10 (45.5) | 10 (35.7) | |||
| Not being able to exercise | Yes | 32 (64) | 15 (68.2) | 17 (60.7) | 0.72 (0.22 to 2.34) | 0.585 |
| No | 18 (36) | 7 (31.8) | 11 (39.3) | |||
| No support from family and friends | Yes | 22 (44) | 13 (59.1) | 9 (32.1) | 0.33 (0.10 to 1.05) | 0.057 |
| No | 28 (56) | 9 (40.9) | 19 (67.9) | |||
| Restrictions of lockdown | Yes | 11 (22) | 7 (31.8) | 4 (14.3) | 0.36 (0.09 to 1.43) | 0.137 |
| No | 39 (78) | 15 (68.2) | 24 (85.7) | |||
| Other health problems | Yes | 21 (42) | 15 (68.2) | 6 (21.4) | 0.13 (0.04 to 0.45) | 0.001 |
| No | 29 (58) | 7 (31.8) | 22 (78.6) | |||
| No face-to-face follow-up | Yes | 30 (60) | 13 (59.1) | 17 (60.7) | 1.07 (0.34 to 3.34) | 0.907 |
| No | 20 (40) | 9 (40.9) | 11 (39.3) | |||
Chi-squared test unless otherwise stated.
Fisher's exact test.
CI, confidence interval; THA, total hip arthroplasty; TKA, total knee arthroplasty.
Patient demographic data and preoperative functional scores for patients undergoing total hip arthroplasty according to group.
| Demographic | Year | OR/difference (95% CI) | p-value | |
|---|---|---|---|---|
| 2019 (n = 192) | 2020 (n = 48) | |||
|
| OR 1.11 (0.58 to 2.12) | 0.743 | ||
| Male | 81 | 19 | ||
| Female | 111 | 29 | ||
| Mean age, yrs (SD) | 69.3 (10.5) | 68.9 (12.2) | Diff 0.4 (-3.1 to 3.9) | 0.821 |
| Mean BMI, kg/m2 (SD) | 28.5 (5.6) | 29.0 (5.1) | Diff 0.5 (-1.3 to 2.2) | 0.603 |
|
| ||||
| No disease | Reference | |||
| Connect tissue | 16 | 3 | OR 0.73 (0.21 to 2.63) | 0.633 |
| Diabetes | 16 | 6 | OR 1.57 (0.58 to 4.26) | 0.371 |
| Back pain | 85 | 22 | OR 1.07 (0.56 to 2.01) | 0.846 |
| Hypertension | 54 | 10 | OR 0.67 (0.31 to 1.44) | 0.307 |
|
| ||||
| Preoperative OHS | 20.5 (9.5) | 20.0 (8.3) | Diff 0.6 (-2.4 to 3.5) | 0.693 |
| Preoperative EQ-5D | 0.387 (0.328) | 0.321 (0.321) | Diff 0.066 (-0.038 to 0.170) | 0.212 |
Chi-squared test.
Independent-samples t-test.
Fisher's exact test.
CI, confidence interval; Diff, difference; EQ-5D, EuroQol five-dimension questionnaire; N/A, not applicable; OHS, Oxford Hip Score; OR, odds ratio; SD, standard deviation.
Patient demographic data and preoperative functional scores for patients undergoing total knee arthroplasty according to group.
| Demographic | Year | OR/difference (95% CI) | p-value | |
|---|---|---|---|---|
| 2019 (n = 223) | 2020 (n = 57) | |||
|
| ||||
| Male | 97 | 25 | OR 0.99 (0.55 to 1.77) | 0.961 |
| Female | 126 | 32 | ||
| Mean age, yrs (SD) | 69.7 (8.6) | 69.7 (8.1) | Diff 0.0 (-2.5 to 2.5) | 0.995 |
| Mean BMI, kg/m2 (SD) | 31.3 (6.5) | 30.9 (6.6) | Diff 0.4 (-1.5 to 2.3) | 0.673 |
|
| ||||
| No disease | Reference | |||
| Connect tissue | 23 | 12 | OR 2.32 (1.07 to 5.00) | 0.029 |
| Diabetes | 31 | 10 | OR 1.32 (0.60 to 2.88) | 0.488 |
| Back pain | 66 | 18 | OR 1.10 (0.59 to 2.06) | 0.771 |
| Hypertension | 59 | 18 | OR 1.28 (0.68 to 2.42) | 0.440 |
|
| ||||
| Preoperative OKS | 20.6 (7.4) | 20.0 (7.6) | Diff 0.6 (-1.6 to 2.8) | 0.570 |
| Preoperative EQ-5D | 0.389 (0.308) | 0.395 (0.312) | Diff 0.006 (-0.084 to 0.097) | 0.890 |
Chi-squared test.
Independent-samples t-test.
CI, confidence interval; Diff, Difference; EQ-5D, EuroQol five-dimension questionnaire; N/A, not applicable; OKS, Oxford Knee Score; OR, odds ratio; SD, standard deviation.
Unadjusted analysis: postoperative outcome measures and the difference relative to preoperative scores for total hip arthroplasty patients according to group.
| Functional measure | Mean (SD) | Difference in mean (95% CI) | p-value | |
|---|---|---|---|---|
| 2019 (n = 192) | 2020 (n = 48) | |||
| Preoperative OHS | 20.5 (9.5) | 19.9 (8.3) | 0.6 (-2.4 to 3.5) | 0.693 |
| Postoperative OHS | 39.3 (8.3) | 36.4 (10.1) | 3.0 (0.2 to 5.7) | 0.035 |
| Mean difference | 18.8 (10.1) | 16.5 (11.2) | 2.4 (-0.9 to 5.6) | 0.158 |
| 95% CI | 17.4 to 20.2 | 13.2 to 19.7 | ||
| p-value | < 0.001 | < 0.001 | ||
| Preoperative EQ-5D | 0.387 (0.328) | 0.321 (0.321) | 0.066 (-0.038 to 0.170) | 0.212 |
| Postoperative EQ-5D | 0.819 (0.179) | 0.705 (0.286) | 0.113 (0.049 to 0.179) | 0.001 |
| Mean difference | 0.433 (0.316) | 0.384 (0.371) | 0.052 (-0.053 to 0.157) | 0.330 |
| 95% CI | 0.387 to 0.478 | 0.276 to 0.491 | ||
| p-value | < 0.001 | < 0.001 | ||
Independent-samples t-test.
Paired t-test.
CI, confidence interval; EQ-5D, EuroQol five-dimension questionnaire; OHS, Oxford Hip Score; SD, standard deviation.
Unadjusted analysis: postoperative outcome measures and the difference relative to preoperative scores for total knee arthroplasty patients according to group.
| Functional measure | Mean (SD) | Difference in mean (95% CI) | p-value | |
|---|---|---|---|---|
| 2019 (n = 223) | 2020 (n = 57) | |||
| Preoperative OKS | 20.6 (7.4) | 20.0 (7.6) | 0.6 (-1.6 to 2.8) | 0.570 |
| Postoperative OKS | 35.1 (9.1) | 35.6 (8.4) | 0.7 (-1.9 to 3.4) | 0.581 |
| Mean difference | 14.5 (11.5) | 15.6 (10.4) | 1.1 (-2.2 to 4.4) | 0.511 |
| 95% CI | 12.9 to 16.1 | 12.8 to 18.4 | ||
| p-value | < 0.001 | < 0.001 | ||
| Preoperative EQ-5D | 0.434 (0.304) | 0.379 (0.344) | 0.006 (-0.084 to 0.969) | 0.890 |
| Postoperative EQ-5D | 0.731 (0.264) | 0.584 (0.408) | 0.017 (-0.048 to 0.085) | 0.580 |
| Mean difference | 0.296 (0.333) | 0.205 (0.374) | 0.004 (-0.096 to 0.104) | 0.941 |
| 95% CI | 0.283 to 0.310 | 0.071 to 0.340 | ||
| p-value | < 0.001 | 0.004 | ||
Independent-samples t-test.
Paired t-test.
CI, confidence interval; EQ-5D, EuroQol five-dimension questionnaire; OKS, Oxford Knee Score; SD, standard deviation.
Rate of satisfaction at one year for total hip arthroplasty and total knee arthroplasty according to group.
| Variable | 2019 | 2020 | OR (95% CI) | p-value |
|---|---|---|---|---|
|
| n = 192 | n = 48 | 0.42 (0.13 to 1.31) | 0.124 |
| Satisfied | 181 | 42 | ||
| Not satisfied | 9 | 5 | ||
| Not answered | 2 | 1 | ||
|
| n = 223 | n = 57 | 1.17 (0.46 to 2.98) | 0.748 |
| Satisfied | 193 | 50 | ||
| Not satisfied | 27 | 6 | ||
| Not answered | 3 | 1 |
Chi-squared test (patients who did not answer were excluded from test).
CI, confidence interval; OR, odds ratio; THA, total hip arthroplasty; TKA, total knee arthroplasty.