| Literature DB >> 33225287 |
Chloe E H Scott1,2, George Holland1, Matilda F R Powell-Bowns1, Caitlin M Brennan1, Matthew Gillespie1, Samuel P Mackenzie1, Nick D Clement1, Anish K Amin1,2, Tim O White1,2, Andrew D Duckworth1,2.
Abstract
AIMS: This study aims to define the epidemiology of trauma presenting to a single centre providing all orthopaedic trauma care for a population of ∼ 900,000 over the first 40 days of the COVID-19 pandemic compared to that presenting over the same period one year earlier. The secondary aim was to compare this with population mobility data obtained from Google.Entities:
Keywords: Adult trauma; COVID-19; Social distancing
Year: 2020 PMID: 33225287 PMCID: PMC7677724 DOI: 10.1302/2633-1462.16.BJO-2020-0043.R1
Source DB: PubMed Journal: Bone Jt Open ISSN: 2633-1462
Timeline of key points in the COVID-19 pandemic in the UK and social distancing measures.
| Date | Event | Population status |
|---|---|---|
| 29/01/20 | First confirmed COVID-19 case in UK | |
| 05/03/20 | First COVID-19 death in UK | COVID-19 aware |
| 14/03/20 | First COVID-19 death in Scotland | |
| 16/03/20 | First Prime Minister briefing to UK public: | Socially distanced |
| 20/03/20 | First formal restrictions in UK: | |
| 23/03/20 | UK lockdown | Lockdown |
| 12/04/20 | Anticipated peak of COVID-19 deaths | |
| 13/04/20 | 40 days after first UK COVID-19 death |
Mean number of orthopaedic referrals per day for the 40-day period 5 March to 13 April in 2019 and 2020.
| Setting | Variable | 2019 | 2020 | p-value | ||
|---|---|---|---|---|---|---|
|
|
|
|
| |||
| All trauma referrals | 45.5 | 43.2 to 48.1 | 26.4 | 22.9 to 30.0 | < 0.001 | |
| Outpatient | TTC | 35.4 | 33.2 to 37.7 | 19.9 | 16.7 to 22.9 | < 0.001 |
| Hospital admissions | All admissions | 10.1 | 8.90 to 11.4 | 6.53 | 5.68 to 7.44 | < 0.001 |
| Operative admissions | 7.0 | 6.08 to 7.97 | 4.0 | 4.00 to 4.00 | < 0.001 | |
| Non-operative admissions | 3.13 | 2.60 to 3.65 | 6.53 | 5.68 to 7.44 | < 0.001 | |
| Fragility factures | 5.03 | 4.28 to 5.87 | 4.23 | 3.68 to 4.83 | 0.173 | |
| Femoral fragility fractures | 2.98 | 2.49 to 3.49 | 2.67 | 2.18 to 3.14 | 0.503 | |
| Non-fragility fractures | 5.1 | 4.36 to 5.86 | 2.30 | 1.75 to 2.85 | < 0.001 | |
Mann Whitney U test.
TTC, trauma triage clinic (new outpatient trauma referrals)
Fig. 1Distribution of inpatient and outpatient trauma volume for the 40-day period 5 March to 13 April 2020. The baseline trauma volume from 2019 is shown in red.
Fig. 2Cumulative number of patients with femoral fragility fractures for the 40-day period 5 March to 13 April for the years 2019 (baseline) and 2020 (COVID-19 pandemic).
Fig. 3Change from baseline in trauma volume and population mobility in the Edinburgh population for a) all trauma and b) patients admitted with fragility and non-fragility trauma.
Mean number of orthopaedic referrals per day for three periods encompassing different social distancing measures: COVID aware (5 to 16 March); formal social distancing (17 to 23 March); and lockdown (24 March to 13 April).
| Setting | COVID-19 aware | Social distancing | Lockdown | p-value | |||
|---|---|---|---|---|---|---|---|
|
|
|
|
|
|
| ||
| All trauma referrals | 41.0 | 36.0 to 46.6 | 22.7 | 18.6 to 26.25 | 19.29 | 16.44 to 22-19 | < 0.001 |
| Outpatient TTC | 32.4 | 28.1 to 37.7 | 17.1 | 14.0 to 20.0 | 13.6 | 11.1 to 15.9 | < 0.001 |
| Hospital admissions | |||||||
| All admissions | 8.58 | 6.94 to 10.1 | 5.57 | 3.67 to 7.50 | 5.67 | 4.61 to 6.71 | 0.020 |
| Operative admissions | 5.67 | 4.43 to 6.87 | 4.29 | 2.60 to 6.17 | 3.86 | 3.00 to 4.76 | 0.109 |
| Non-operative admissions | 2.92 | 2.15 to 3.67 | 1.29 | 0.33 to 2.83 | 1.81 | 1.33 to 2.32 | 0.013 |
| Fragility factures | 5.42 | 4.18 to 6.67 | 3.57 | 2.75 to 4.43 | 3.76 | 3.1 to 4.45 | 0.065 |
| Femoral fragility fractures | 3.42 | 2.5 to 4.29 | 2.43 | 1.0 to 4.0 | 2.33 | 1.77 to 2.9 | 0.169 |
| Non-fragility fractures | 3.17 | 2.0 to 4.3 | 2.0 | 0.75 to 3.25 | 1.9 | 1.20 to 2.56 | 0.194 |
TTC, trauma triage clinic (new outpatient trauma referrals).
Kruskal Wallis
Patient characteristics for orthopaedic admissions. Median (IQR), number (%).
| Variable | 2019 (n = 405) | 2020 (n = 261) | p-value |
|---|---|---|---|
| Age, median (IQR) | 70 (49 to 83) | 78 (59 to 86) | < 0.001 |
| Female sex, n (%) | 246 (61) | 159 (61) | 0.963 |
| Residency outside Edinburgh, n (%) | 29 (7) | 1 (1) | < 0.001 |
|
| |||
| (most deprived) Quintile 1 | 48 (12) | 28 (11) | 0.396 |
| 2 | 79 (20) | 53 (20) | |
| 3 | 78 (39) | 51 (20) | |
| 4 | 75 (19) | 38 (15) | |
| (least deprived) Quintile 5 | 106 (26) | 86 (33) | |
|
| 0 (0 to 0) | 0 (0 to 0) | 0.073 |
|
| |||
| Polytrauma | 23 (6) | 0 (0) | < 0.001 |
| Fragility fracture | 201 (50) | 169 (65) | < 0.001 |
|
| |||
| Upper limb injury | 86 (27) | 33 (17) | 0.017 |
| Lower limb injury | 228 (73) | 166 (83) | |
|
| 0.023 | ||
|
| 270 (67) | 196 (75) | 0.017 |
| From standing | 235 (58) | 171 (66) | |
| Downstairs | 9 (2) | 4 (2) | |
| From height < 2 metres | 6 (1) | 10 (4) | |
| From height > 2 metres | 20 (5) | 11 (4) | |
|
| 23 (6) | 12 (5) | 0.549 |
| Pedestrian hit by vehicle | 4 (1) | 2 (1) | |
| Cyclist fall or hit by vehicle | 8 (2) | 4 (2) | |
| Motor cyclist fall or hit by vehicle | 7 (2) | 3 (1) | |
| Occupant of vehicle | 4 (1) | 3 (1) | |
|
| 28 (7) | 3 (1) | 0.001 |
| Assault | 4 (1) | 0 (0) | |
| Direct blow/crush | 4 (1) | 1 (1) | |
| Other | 6 (1) | 5 (2) | |
| Atraumatic | 70 (17) | 43 (16) | |
|
| 44 (11) | 13 (5) | 0.011 |
IQR, interquartile range; SIMD, Scottish Index of Multiple Deprivation.
Mann-Whitney U test
Chi square
Patient characteristics for trauma outpatient referrals. Median (IQR), number (%)
| Variable | 2019 (n = 1415) | 2020 (n = 795) | p-value |
|---|---|---|---|
| Age, median (IQR) | 42 (21 to 60) | 44 (27 to 64) | 0.001 |
| Female sex, n (%) | 702(50) | 423 (53) | 0.108 |
|
| 0.043 | ||
| (most deprived) Quintile 1 | 201 (14) | 136 (17) | |
| 2 | 312 (22) | 159 (20) | |
| 3 | 233 (16) | 103 (13) | |
| 4 | 257 (18) | 134 (17) | |
| (least deprived) Quintile 5 | 373 (26) | 232 (29) | |
|
| < 0.001 | ||
| Home | 487 (34) | 338 (42) | |
| Care Institution or hospital | 3 (0) | 2 (1) | |
| Educational establishment | 47 (3) | 20 (3) | |
| Public place | 391 (28) | 245 (31) | |
| Sports or leisure facility | 210 (15) | 54 (7) | |
| Roads or transport | 11 (1) | 1 (1) | |
| Pub or club | 8 (1) | 2 (1) | |
| Other | 159 (11) | 72 (9) | |
|
| 0.513 | ||
| Upper limb injury | 958 (68) | 557 (70) | |
| Lower limb injury | 450 (32) | 234 (30) | |
|
| < 0.001 | ||
|
| |||
| From height < 2 metres | 387 (27) | 280 (35) | |
| From height > 2 metres | 14 (1) | 3 (1) | |
|
| |||
| Pedestrian hit by vehicle | 2 (1) | 2 (1) | |
| Cyclist fall or hit by vehicle | 18 (1) | 11 (1) | |
| Motor cyclist fall or hit by vehicle | 10 (1) | 5 (1) | |
| Occupant of vehicle | 6 (1) | 1 (1) | |
|
| 231 (16) | 88 (11) | |
| Atraumatic | 0 (0) | 1 (1) | |
| Assault | 21 (1) | 4 (1) | |
| Other | 611 (43) | 399 (50) |
IQR, interquartile range; SIMD, Scottish Index of Multiple Deprivation.
Mann-Whitney U test
Chi squared
Correlations between trauma volume differences from baseline and population mobility differences from baseline as reported by Google.
| Type of activity | All trauma | Operative admissions | Nonoperative admissions | TTC | ||||
|---|---|---|---|---|---|---|---|---|
| PC | p-value | PC | p-value | PC | p-value | PC | p-value | |
| Retail and recreation | 0.825 | < 0.001 | 0.256 | 0.157 | 0.346 | 0.066 | 0.797 | < 0.001 |
| Grocery and pharmacy | 0.653 | < 0.001 | 0.147 | 0.422 | 0.434 | 0.019 | 0.622 | < 0.001 |
| Parks | 0.767 | < 0.001 | 0.250 | 0.167 | 0.251 | 0.188 | 0.725 | < 0.001 |
| Transit stations | 0.817 | < 0.001 | 0.307 | 0.087 | 0.330 | 0.080 | 0.778 | < 0.001 |
| Work | 0.786 | < 0.001 | 0.301 | 0.094 | 0.378 | 0.043 | 0.737 | < 0.001 |
| All activities | 0.749 | < 0.001 | 0.271 | 0.133 | 0.360 | 0.055 | 0.775 | < 0.001 |
PC = Pearson’s correlation.; TTC, trauma triage clinic referrals