Cristina Peris-Martínez1,2,3, María Amparo Díez-Ajenjo1,4, María Carmen García-Domene1,4, María Dolores Pinazo-Durán2, María José Luque-Cobija1,4, María Ángeles Del Buey-Sayas5, Susana Ortí-Navarro4. 1. FISABIO Oftalmología Médica (FOM), Anterior Segment and Cornea and External Eye Diseases Unit, Bifurcación Pío Baroja-General Avilés, 12, E-46015 Valencia, Spain. 2. Surgery Department, Ophthalmology, School of Medicine, University of Valencia, Av. Blasco Ibáñez, 15, E-46010 Valencia, Spain. 3. Aviño Peris Eye Clinic, Avinguda de l'Oest, 34, E-46001 Valencia, Spain. 4. Optics, Optometry and Vision Sciences Department, School of Physics, University of Valencia, Dr. Moliner, 50, E-46100 Valencia, Spain. 5. Hospital Lozano Blesa, Anterior Segment and Cornea and External Eye Diseases, E-46015 Zaragoza, Spain.
Abstract
(1) Purpose: To assess the main corneal response differences between normal and subclinical keratoconus (SCKC) with a Corvis® ST device. (2) Material and Methods: We selected 183 eyes of normal patients, of a mean age of 33 ± 9 years and 16 eyes of patients with SCKC of a similar mean age. We measured best corrected visual acuity (BCVA) and corneal topography with a Pentacam HD device to select the SCKC group. Biomechanical measurements were performed using the Corvis® ST device. We carried out a non-parametric analysis of the data with SPSS software (Wilcoxon signed rank-test). (3) Results: We found statistically significant differences between the control and SCKC groups in some corneal biomechanical parameters: first and second applanation time (p = 0.05 and p = 0.02), maximum deformation amplitude (p = 0.016), highest concavity radius (p = 0.007), and second applanation length and corneal velocity ((p = 0.039 and p = 0.016). (4) Conclusions: Our results show that the use of normalised biomechanical parameters provided by noncontact tonometry, combined with a discriminant function theory, is a useful tool for detecting subclinical keratoconus.
(1) Purpose: To assess the main corneal response differences between normal and subclinical keratoconus (SCKC) with a Corvis® ST device. (2) Material and Methods: We selected 183 eyes of normal patients, of a mean age of 33 ± 9 years and 16 eyes of patients with SCKC of a similar mean age. We measured best corrected visual acuity (BCVA) and corneal topography with a Pentacam HD device to select the SCKC group. Biomechanical measurements were performed using the Corvis® ST device. We carried out a non-parametric analysis of the data with SPSS software (Wilcoxon signed rank-test). (3) Results: We found statistically significant differences between the control and SCKC groups in some corneal biomechanical parameters: first and second applanation time (p = 0.05 and p = 0.02), maximum deformation amplitude (p = 0.016), highest concavity radius (p = 0.007), and second applanation length and corneal velocity ((p = 0.039 and p = 0.016). (4) Conclusions: Our results show that the use of normalised biomechanical parameters provided by noncontact tonometry, combined with a discriminant function theory, is a useful tool for detecting subclinical keratoconus.
Authors: David Smadja; David Touboul; Ayala Cohen; Etti Doveh; Marcony R Santhiago; Glauco R Mello; Ronald R Krueger; Joseph Colin Journal: Am J Ophthalmol Date: 2013-06-07 Impact factor: 5.258
Authors: Keith M Meek; Stephen J Tuft; Yifei Huang; Paulvinder S Gill; Sally Hayes; Richard H Newton; Anthony J Bron Journal: Invest Ophthalmol Vis Sci Date: 2005-06 Impact factor: 4.799
Authors: Marcos A Crespo; Hiram J Jimenez; Tanmay Deshmukh; Jose S Pulido; Ahmed Saeed Saad; Frederick H Silver; Dominick A Benedetto; Christopher J Rapuano; Zeba A Syed Journal: Transl Vis Sci Technol Date: 2022-07-08 Impact factor: 3.048