| Literature DB >> 3388044 |
B G Robinson1, D M Frim, W J Schwartz, J A Majzoub.
Abstract
Daily variation has been found in the length of the polyadenylate tail attached to vasopressin messenger RNA in the suprachiasmatic nuclei, which is the location of an endogenous circadian pacemaker in mammals. No such variation was found in the supraoptic or paraventricular nuclei. This variation in the length of the polyadenylate tail may underlie the circadian rhythm of vasopressin peptide levels in cerebrospinal fluid and is a unique example of a daily rhythm in messenger RNA structure.Entities:
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Year: 1988 PMID: 3388044 DOI: 10.1126/science.3388044
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728