| Literature DB >> 33857575 |
Jose F Huizar1, Alex Y Tan2, Karoly Kaszala2, Kenneth A Ellenbogen3.
Abstract
The medical community's understanding of the consequences of premature ventricular contractions (PVCs) and PVC-induced cardiomyopathy has been derived mostly from observational and large population-based studies. Due to the difficulty of predicting the development of PVC-cardiomyopathy, the acute and chronic cardiac effects of PVCs and the mechanism of PVC-cardiomyopathy have been derived from pre-clinical studies with large animal models. Recently, these studies have described myocardial substrates that could potentially increase morbidity and mortality in patients with frequent PVCs and PVC-cardiomyopathy. In this paper, we provide an up-to-date comprehensive review of these pre-clinical and clinical studies. Published by Elsevier Inc.Entities:
Keywords: Eccentric hypertrophy; Heart rate irregularity; LV dyssynchrony; Premature atrial contraction; Premature ventricular contraction
Mesh:
Year: 2021 PMID: 33857575 PMCID: PMC9192164 DOI: 10.1016/j.pcad.2021.04.001
Source DB: PubMed Journal: Prog Cardiovasc Dis ISSN: 0033-0620 Impact factor: 11.278