| Literature DB >> 33835290 |
Lei Zhao1, Erin C Kaser2, Kyle P D'mello2, Ziwen Zhu3, Huaping Xiao2,4, Mark R Wakefield3, Qian Bai3, Yujiang Fang5,6.
Abstract
Interleukins are signaling molecules involved in the immune system, and they play a variety of roles in different diseases and cancers. Acute myeloid leukemia (AML) is the most common type of leukemia in adults, and survival rate after diagnosis is very low. Investigating the role interleukins play in AML can help understand the progression of the disease. There exists a need for more effective treatment of AML. Interleukins can be used to guide immunotherapy for AML. This review article will examine how specific interleukins play a role in AML disease progression and how they can be utilized as a future treatment option.Entities:
Keywords: Acute myeloid leukemia (AML); Interleukins (ILs); Leukemia
Year: 2021 PMID： 33835290 DOI： 10.1007/s12032-021-01498-7
Source DB: PubMed Journal: Med Oncol ISSN： 1357-0560 Impact factor: 3.064