Literature DB >> 31821407

IKZF1 deletions in pediatric acute lymphoblastic leukemia: still a poor prognostic marker?

Martin Stanulla1, Hélène Cavé2,3, Anthony V Moorman4.   

Abstract

Improved personalized adjustment of primary therapy to the perceived risk of relapse by using new prognostic markers for treatment stratification may be beneficial to patients with acute lymphoblastic leukemia (ALL). Here, we review the advances that have shed light on the role of IKZF1 aberration as prognostic factor in pediatric ALL and summarize emerging concepts in this field. Continued research on the interplay of disease biology with exposure and response to treatment will be key to further improve treatment strategies.
© 2020 by The American Society of Hematology.

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Year:  2020        PMID： 31821407      PMCID： PMC7019035          DOI： 10.1182/blood.2019000813

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  68 in total

Review 1.  Ikaros, Aiolos and Helios: transcription regulators and lymphoid malignancies.

Authors:  Angelita Rebollo; Christian Schmitt
Journal:  Immunol Cell Biol       Date:  2003-06       Impact factor: 5.126

2.  Prognostic value of rare IKZF1 deletion in childhood B-cell precursor acute lymphoblastic leukemia: an international collaborative study.

Authors:  J M Boer; A van der Veer; D Rizopoulos; M Fiocco; E Sonneveld; H A de Groot-Kruseman; R P Kuiper; P Hoogerbrugge; M Horstmann; M Zaliova; C Palmi; J Trka; E Fronkova; M Emerenciano; M do Socorro Pombo-de-Oliveira; W Mlynarski; T Szczepanski; K Nebral; A Attarbaschi; N Venn; R Sutton; C J Schwab; A Enshaei; A Vora; M Stanulla; M Schrappe; G Cazzaniga; V Conter; M Zimmermann; A V Moorman; R Pieters; M L den Boer
Journal:  Leukemia       Date:  2015-07-23       Impact factor: 11.528

3.  Deregulation of DUX4 and ERG in acute lymphoblastic leukemia.

Authors:  Jinghui Zhang; Kelly McCastlain; Hiroki Yoshihara; Beisi Xu; Yunchao Chang; Michelle L Churchman; Gang Wu; Yongjin Li; Lei Wei; Ilaria Iacobucci; Yu Liu; Chunxu Qu; Ji Wen; Michael Edmonson; Debbie Payne-Turner; Kerstin B Kaufmann; Shin-Ichiro Takayanagi; Erno Wienholds; Esmé Waanders; Panagiotis Ntziachristos; Sofia Bakogianni; Jingjing Wang; Iannis Aifantis; Kathryn G Roberts; Jing Ma; Guangchun Song; John Easton; Heather L Mulder; Xiang Chen; Scott Newman; Xiaotu Ma; Michael Rusch; Pankaj Gupta; Kristy Boggs; Bhavin Vadodaria; James Dalton; Yanling Liu; Marcus L Valentine; Li Ding; Charles Lu; Robert S Fulton; Lucinda Fulton; Yashodhan Tabib; Kerri Ochoa; Meenakshi Devidas; Deqing Pei; Cheng Cheng; Jun Yang; William E Evans; Mary V Relling; Ching-Hon Pui; Sima Jeha; Richard C Harvey; I-Ming L Chen; Cheryl L Willman; Guido Marcucci; Clara D Bloomfield; Jessica Kohlschmidt; Krzysztof Mrózek; Elisabeth Paietta; Martin S Tallman; Wendy Stock; Matthew C Foster; Janis Racevskis; Jacob M Rowe; Selina Luger; Steven M Kornblau; Sheila A Shurtleff; Susana C Raimondi; Elaine R Mardis; Richard K Wilson; John E Dick; Stephen P Hunger; Mignon L Loh; James R Downing; Charles G Mullighan
Journal:  Nat Genet       Date:  2016-10-24       Impact factor: 38.330

4.  IKZF1 deletions predict a poor prognosis in children with B-cell progenitor acute lymphoblastic leukemia: a multicenter analysis in Taiwan.

Authors:  Yung-Li Yang; Chia-Cheng Hung; Jiann-Shiuh Chen; Kai-Hsin Lin; Shiann-Tarng Jou; Chih-Cheng Hsiao; Jiunn-Ming Sheen; Chao-Neng Cheng; Kang-Hsi Wu; Shu-Rung Lin; Sung-Liang Yu; Hsuan-Yu Chen; Meng-Yao Lu; Shih-Chung Wang; Hsiu-Hao Chang; Shu-Wha Lin; Yi-Ning Su; Dong-Tsamn Lin
Journal:  Cancer Sci       Date:  2011-08-12       Impact factor: 6.716

5.  Efficacy of Retinoids in IKZF1-Mutated BCR-ABL1 Acute Lymphoblastic Leukemia.

Authors:  Michelle L Churchman; Jonathan Low; Chunxu Qu; Elisabeth M Paietta; Lawryn H Kasper; Yunchao Chang; Debbie Payne-Turner; Mark J Althoff; Guangchun Song; Shann-Ching Chen; Jing Ma; Michael Rusch; Dan McGoldrick; Michael Edmonson; Pankaj Gupta; Yong-Dong Wang; William Caufield; Burgess Freeman; Lie Li; John C Panetta; Sharyn Baker; Yung-Li Yang; Kathryn G Roberts; Kelly McCastlain; Ilaria Iacobucci; Jennifer L Peters; Victoria E Centonze; Faiyaz Notta; Stephanie M Dobson; Sasan Zandi; John E Dick; Laura Janke; Junmin Peng; Kiran Kodali; Vishwajeeth Pagala; Jaeki Min; Anand Mayasundari; Richard T Williams; Cheryl L Willman; Jacob Rowe; Selina Luger; Ross A Dickins; R Kiplin Guy; Taosheng Chen; Charles G Mullighan
Journal:  Cancer Cell       Date:  2015-08-27       Impact factor: 31.743

6.  IKZF1 deletion is an independent prognostic marker in childhood B-cell precursor acute lymphoblastic leukemia, and distinguishes patients benefiting from pulses during maintenance therapy: results of the EORTC Children's Leukemia Group study 58951.

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Journal:  Leukemia       Date:  2015-06-08       Impact factor: 11.528

7.  Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia.

Authors:  Charles G Mullighan; Xiaoping Su; Jinghui Zhang; Ina Radtke; Letha A A Phillips; Christopher B Miller; Jing Ma; Wei Liu; Cheng Cheng; Brenda A Schulman; Richard C Harvey; I-Ming Chen; Robert J Clifford; William L Carroll; Gregory Reaman; W Paul Bowman; Meenakshi Devidas; Daniela S Gerhard; Wenjian Yang; Mary V Relling; Sheila A Shurtleff; Dario Campana; Michael J Borowitz; Ching-Hon Pui; Malcolm Smith; Stephen P Hunger; Cheryl L Willman; James R Downing
Journal:  N Engl J Med       Date:  2009-01-07       Impact factor: 91.245

8.  Germline genomic variants associated with childhood acute lymphoblastic leukemia.

Authors:  Lisa R Treviño; Wenjian Yang; Deborah French; Stephen P Hunger; William L Carroll; Meenakshi Devidas; Cheryl Willman; Geoffrey Neale; James Downing; Susana C Raimondi; Ching-Hon Pui; William E Evans; Mary V Relling
Journal:  Nat Genet       Date:  2009-08-16       Impact factor: 38.330

9.  Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL.

Authors:  Arian van der Veer; Esmé Waanders; Rob Pieters; Marieke E Willemse; Simon V Van Reijmersdal; Lisa J Russell; Christine J Harrison; William E Evans; Vincent H J van der Velden; Peter M Hoogerbrugge; Frank Van Leeuwen; Gabriele Escherich; Martin A Horstmann; Leila Mohammadi Khankahdani; Dimitris Rizopoulos; Hester A De Groot-Kruseman; Edwin Sonneveld; Roland P Kuiper; Monique L Den Boer
Journal:  Blood       Date:  2013-08-23       Impact factor: 22.113

10.  Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of EP300 and CREBBP.

Authors:  Maoxiang Qian; Hui Zhang; Shirley Kow-Yin Kham; Shuguang Liu; Chuang Jiang; Xujie Zhao; Yi Lu; Charnise Goodings; Ting-Nien Lin; Ranran Zhang; Takaya Moriyama; Zhaohong Yin; Zhenhua Li; Thuan Chong Quah; Hany Ariffin; Ah Moy Tan; Shuhong Shen; Deepa Bhojwani; Shaoyan Hu; Suning Chen; Huyong Zheng; Ching-Hon Pui; Allen Eng-Juh Yeoh; Jun J Yang
Journal:  Genome Res       Date:  2016-11-30       Impact factor: 9.043
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  20 in total

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Journal:  Curr Oncol Rep       Date:  2020-11-14       Impact factor: 5.075

Review 2.  The role of various interleukins in acute myeloid leukemia.

Authors:  Lei Zhao; Erin C Kaser; Kyle P D'mello; Ziwen Zhu; Huaping Xiao; Mark R Wakefield; Qian Bai; Yujiang Fang
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Review 3.  Cell-intrinsic view of the aryl hydrocarbon receptor in tumor immunity.

Authors:  Joseph W Dean; Liang Zhou
Journal:  Trends Immunol       Date:  2022-02-05       Impact factor: 16.687

4.  Modeling IKZF1 lesions in B-ALL reveals distinct chemosensitivity patterns and potential therapeutic vulnerabilities.

Authors:  Jason H Rogers; Rohit Gupta; Jaime M Reyes; Michael C Gundry; Geraldo Medrano; Anna Guzman; Rogelio Aguilar; Shannon E Conneely; Tidie Song; Cade Johnson; Sean Barnes; Carlo D D Cristobal; Kristen Kurtz; Lorenzo Brunetti; Margaret A Goodell; Rachel E Rau
Journal:  Blood Adv       Date:  2021-10-12

5.  Gene Mutations Related to Glucocorticoid Resistance in Pediatric Acute Lymphoblastic Leukemia.

Authors:  JinFang Zhang; LingJi Zeng; YuLian Wang; JianWei Pan; XingDong Li; Bei Feng; Quan Yang
Journal:  Front Pediatr       Date:  2022-06-06       Impact factor: 3.569

6.  Bioinformatics analysis to screen key prognostic genes in the breast cancer tumor microenvironment.

Authors:  Qian Ye; Xiaowen Han; Zhengsheng Wu
Journal:  Bioengineered       Date:  2020-12       Impact factor: 3.269

7.  Impact of high-risk cytogenetics on outcomes for children and young adults receiving CD19-directed CAR T-cell therapy.

Authors:  Allison Barz Leahy; Kaitlin J Devine; Yimei Li; Hongyan Liu; Regina Myers; Amanda DiNofia; Lisa Wray; Susan R Rheingold; Colleen Callahan; Diane Baniewicz; Maria Patino; Haley Newman; Stephen P Hunger; Stephan A Grupp; David M Barrett; Shannon L Maude
Journal:  Blood       Date:  2022-04-07       Impact factor: 25.476

8.  Ikaros antagonizes DNA binding by STAT5 in pre-B cells.

Authors:  Beate Heizmann; Stéphanie Le Gras; Célestine Simand; Patricia Marchal; Susan Chan; Philippe Kastner
Journal:  PLoS One       Date:  2020-11-12       Impact factor: 3.240

9.  Copy Number Alteration Profile Provides Additional Prognostic Value for Acute Lymphoblastic Leukemia Patients Treated on BFM Protocols.

Authors:  Mirella Ampatzidou; Lina Florentin; Vassilios Papadakis; Georgios Paterakis; Marianna Tzanoudaki; Dimitra Bouzarelou; Stefanos I Papadhimitriou; Sophia Polychronopoulou
Journal:  Cancers (Basel)       Date:  2021-06-30       Impact factor: 6.639

10.  Comprehensive Analysis of Peritoneal Metastasis Sequencing Data to Identify LINC00924 as a Prognostic Biomarker in Gastric Cancer.

Authors:  Yan Fang; Sihao Huang; Lei Han; Shuyi Wang; Bin Xiong
Journal:  Cancer Manag Res       Date:  2021-07-12       Impact factor: 3.989
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