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Literature DB >> 33649304

DNA stability: a central design consideration for DNA data storage systems.

Karishma Matange¹, James M Tuck², Albert J Keung³.

Abstract

Data storage in DNA is a rapidly evolving technology that could be a transformative solution for the rising energy, materials, and space needs of modern information storage. Given that the information medium is DNA itself, its stability under different storage and processing conditions will fundamentally impact and constrain design considerations and data system capabilities. Here we analyze the storage conditions, molecular mechanisms, and stabilization strategies influencing DNA stability and pose specific design configurations and scenarios for future systems that best leverage the considerable advantages of DNA storage.

Entities: Chemical Disease Species

Year: 2021 PMID： 33649304 DOI： 10.1038/s41467-021-21587-5

Source DB: PubMed Journal: Nat Commun ISSN： 2041-1723 Impact factor: 14.919

26 in total

DNA stability: a central design consideration for DNA data storage systems.

1. Amino acid racemization in amber-entombed insects: implications for DNA preservation.

2. Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid.

Review 3. Synthetic DNA Synthesis and Assembly: Putting the Synthetic in Synthetic Biology.

4. DNA Fountain enables a robust and efficient storage architecture.

5. How to stop data centres from gobbling up the world's electricity.

6. The unusual origin of the polymerase chain reaction.

7. Assessment of DNA encapsulation, a new room-temperature DNA storage method.

8. A DNA-of-things storage architecture to create materials with embedded memory.

9. Molecular computation of solutions to combinatorial problems.

Review 10. Molecular digital data storage using DNA.

1. Formation and Repair of an Interstrand DNA Cross-Link Arising from a Common Endogenous Lesion.

2. Information decay and enzymatic information recovery for DNA data storage.

3. The bug in a teacup-monitoring arthropod-plant associations with environmental DNA from dried plant material.

Review 4. Design considerations for advancing data storage with synthetic DNA for long-term archiving.

5. Bioorthogonal information storage in L-DNA with a high-fidelity mirror-image Pfu DNA polymerase.

6. PAMAM-calix-dendrimers: Synthesis and Thiacalixarene Conformation Effect on DNA Binding.

7. Multi-Domains in a Single Lattice Formed by DNA Self-Assembly.

8. In vivo processing of digital information molecularly with targeted specificity and robust reliability.

9. Hidden Addressing Encoding for DNA Storage.

10. Promiscuous molecules for smarter file operations in DNA-based data storage.